Navigation Links
University of Nevada, Reno first to show transgenerational effect of antibiotics
Date:4/27/2012

RENO, Nev. In a paper published today in Nature's open access journal Scientific Reports, researchers at the University of Nevada, Reno report that male pseudoscorpions treated with the antibiotic tetracycline suffer significantly reduced sperm viability and pass this toxic effect on to their untreated sons. They suggest that a similar effect could occur in humans and other species.

"This is the first research to show a transgenerational effect of antibiotics," David Zeh, chair of the Department of Biology in the College of Science, said. "Tetracycline has a significant detrimental effect on male reproductive function and sperm viability of pseudoscorpions reducing viability by up to 25 percent and now we know that effect is passed on to the next generation. We didn't see the effect in subsequent generations."

The research involved a three-generation study of the pseudoscorpion, Cordylochernes scorpioides, a small scorpion-like arachnid. To control for genetic influences, in the first generation, brothers and sisters from each of 21 broods were either treated with weekly doses of tetracycline from birth to adulthood or were reared as untreated controls. Subsequent generations were not treated with tetracycline. The antibiotic had no effect on male or female body size, sperm number or female reproduction, they found.

In the article, lead author and assistant biology professor Jeanne Zeh surmises that tetracycline may induce epigenetic changes in male reproductive tissues that may be passed to sons changes that do not alter the sequence of DNA but rather alter the way genes are expressed.

The broad-spectrum antibiotic tetracycline is commonly used in animal production, antimicrobial therapy, and for curing arthropods infected with bacterial endosymbionts such as Wolbachia. Despite more than six decades of therapeutic and agricultural use that has resulted in the evolution of widespread bacterial resistance, tetracycline is still commonly used as an additive in animal feed and as an accessible antimicrobial therapy in developing countries.


'/>"/>
Contact: Mike Wolterbeek
mwolterbeek@unr.edu
University of Nevada, Reno
Source:Eurekalert  

Related biology news :

1. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
2. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
3. University of Minnesota startup offers game-changing energy solutions that reduce CO2 emissions
4. Israel names Tel Aviv Universitys Renewable Energy Center a Center of Research Excellence
5. University of Minnesota invention helps advance reliability of alternative energy
6. University of Toronto biologists predict extinction for organisms with poor quality genes
7. Life expectancy may affect when you get married, divorced, have kids: Queens University study
8. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
9. University leads £6 million EU project to tackle obesity
10. Marshall University study may lead to new treatments for prostate cancer
11. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Nevada, Reno first to show transgenerational effect of antibiotics
(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
(Date:4/13/2016)... , April 13, 2016  IMPOWER physicians supporting ... are setting a new clinical standard in telehealth thanks ... By leveraging the higi platform, IMPOWER patients can routinely ... pulse and body mass index, and, when they opt ... and convenient visit to a local retail location at ...
(Date:3/23/2016)... WAKEFIELD, Massachusetts , March 23, 2016 ... kombiniert im Interesse erhöhter Sicherheit Gesichts- und ... Xura, Inc. (NASDAQ: MESG ... heute bekannt, dass das Unternehmen mit SpeechPro ... insbesondere aus der Finanzdienstleistungsbranche, wird die Möglichkeit ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... The American Medical ... Office of the National Coordinator for Health IT (ONC) outlining a measurement approach ... data were available when and where it was needed. The organization of health ...
(Date:5/25/2016)... , ... May 25, 2016 , ... WEDI, the nation’s ... exchange, today announced that Charles W. Stellar has been named by the WEDI Board ... since January 2016. As an executive leader with more than 35 years of experience ...
(Date:5/25/2016)... Connecticut (PRWEB) , ... May 25, 2016 , ... ... the U.S. Food and Drug Administration (FDA) has granted the company’s orphan drug ... the company’s second orphan drug designation granted by the FDA. , Spinocerebellar ...
(Date:5/24/2016)... TEL AVIV, Israel , May 24, 2016   ... on providing physicians with artificial intelligence, real-time decision support tools ... selected to present at the 2016 Israeli Advanced Technology Industries ... part of Israel,s 15th National Life ... to 26th at the David Intercontinental Hotel in ...
Breaking Biology Technology: