Navigation Links
University of Nevada, Reno first to show transgenerational effect of antibiotics
Date:4/27/2012

RENO, Nev. In a paper published today in Nature's open access journal Scientific Reports, researchers at the University of Nevada, Reno report that male pseudoscorpions treated with the antibiotic tetracycline suffer significantly reduced sperm viability and pass this toxic effect on to their untreated sons. They suggest that a similar effect could occur in humans and other species.

"This is the first research to show a transgenerational effect of antibiotics," David Zeh, chair of the Department of Biology in the College of Science, said. "Tetracycline has a significant detrimental effect on male reproductive function and sperm viability of pseudoscorpions reducing viability by up to 25 percent and now we know that effect is passed on to the next generation. We didn't see the effect in subsequent generations."

The research involved a three-generation study of the pseudoscorpion, Cordylochernes scorpioides, a small scorpion-like arachnid. To control for genetic influences, in the first generation, brothers and sisters from each of 21 broods were either treated with weekly doses of tetracycline from birth to adulthood or were reared as untreated controls. Subsequent generations were not treated with tetracycline. The antibiotic had no effect on male or female body size, sperm number or female reproduction, they found.

In the article, lead author and assistant biology professor Jeanne Zeh surmises that tetracycline may induce epigenetic changes in male reproductive tissues that may be passed to sons changes that do not alter the sequence of DNA but rather alter the way genes are expressed.

The broad-spectrum antibiotic tetracycline is commonly used in animal production, antimicrobial therapy, and for curing arthropods infected with bacterial endosymbionts such as Wolbachia. Despite more than six decades of therapeutic and agricultural use that has resulted in the evolution of widespread bacterial resistance
'/>"/>

Contact: Mike Wolterbeek
mwolterbeek@unr.edu
University of Nevada, Reno
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
2. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
3. University of Minnesota startup offers game-changing energy solutions that reduce CO2 emissions
4. Israel names Tel Aviv Universitys Renewable Energy Center a Center of Research Excellence
5. University of Minnesota invention helps advance reliability of alternative energy
6. University of Toronto biologists predict extinction for organisms with poor quality genes
7. Life expectancy may affect when you get married, divorced, have kids: Queens University study
8. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
9. University leads £6 million EU project to tackle obesity
10. Marshall University study may lead to new treatments for prostate cancer
11. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Nevada, Reno first to show transgenerational effect of antibiotics
(Date:5/7/2015)... 2015 Fingerprint Cards (FPC) ... FPC1035, FPC,s smallest touch fingerprint sensors to date.  ... for integration on the backside of the phone, ... possibilities to integrate touch fingerprint sensors in the ... possibilities for module manufacturers to customize the look ...
(Date:4/27/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces that its Wocket® ... first week of May, 2015 and will be fulfilling ... Gino Pereira , Chief Executive Officer ... as Wocket® enters the consumer market. We would like ...
(Date:4/20/2015)... The announcement comes as demand ... Management (GRM), Ireland,s foremost records management ... built up an impressive track record of clients within the ... the records management sector in Dubai . ... staffbase and employ a further eight staff members at its ...
Breaking Biology News(10 mins):FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... study that looked at consumers who buy locally ... community-supported agriculture programs found the venues largely attract ... findings present a need for broadening local food ... payment plans and strategic efforts that make fresh ...
... are linked to one of the most lethal forms of ... of the genes found in the study are frequently altered ... of tumors. The findings appear in the Oct. 28, 2012, ... was led by researchers from the National Human Genome Research ...
... SAN FRANCISCO, CAOctober 28, 2012 Scientists at the Gladstone ... discovered how modifying a gene halts the toxic buildup ... point to a potential new tactic for treating a ... or Lou Gehrig,s disease)a fatal disease for which there ...
Cached Biology News:Greater effort needed to move local, fresh foods beyond 'privileged' consumers 2NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer 2NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer 3NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer 4Gladstone, Stanford scientists block toxic protein that plays key role in Lou Gehrig's disease 2Gladstone, Stanford scientists block toxic protein that plays key role in Lou Gehrig's disease 3
(Date:5/27/2015)... May 27, 2015  RXi Pharmaceuticals Corporation (NASDAQ: ... discovering and developing innovative therapies primarily in the ... on the status of the Company,s Series A ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ... 21 shares of Series A Preferred Stock and ...
(Date:5/26/2015)... (PRWEB) May 26, 2015 WORMS, ... Grace & Co. (NYSE: GRA) announces that its ... manufacturing practice (GMP) certification from EXCiPACTâ„¢, an independent ... pharmaceutical excipients. , All three Grace ... pharmaceutical grade excipient silica gels have now received ...
(Date:5/26/2015)... May 26, 2015   Intrexon Corporation (NYSE: ... Gregory Frost , Ph.D., Senior Vice President and Head ... Global Healthcare Conference on Wednesday, June 3 rd , at ... New York City . About Intrexon ... Powering the Bioindustrial Revolution with Better DNA ™ to ...
(Date:5/26/2015)... ORANGEBURG, N.Y. , May 26, 2015 /PRNewswire/ ... products and solutions, today announced that Oakwood Healthcare ... been selected as the winning entry in ... recognizing industry professionals who display excellence in building ... services (ES) teams in healthcare facilities.  ...
Breaking Biology Technology:RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 2RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 3CORRECTION: Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2Intrexon to Present at the Jefferies 2015 Global Healthcare Conference 2PDI Announces Winner in Delivering the Difference Contest 2PDI Announces Winner in Delivering the Difference Contest 3
... Virginia Key, Fla. Climate models have long predicted ... precipitation events. A new study conducted at the University ... the first observational evidence to confirm the link between ... One of the most serious challenges humanity will face ...
... DIEGO, Aug. 7 SGX Pharmaceuticals,(Nasdaq: SGXP ) today ... June 30, 2008. For the three months ended June 30, ... loss of $7.2 million. For,the six months ended June 30, ... million. The revenue in the six month period includes $10.8,million ...
... (Nasdaq: ISTA ), today reported financial results for the ... $17.8 million for the,quarter ended June 30, 2008, a 31% ... the second quarter ended June 30, 2008, was $8.5 million,(or ... $8.7 million (or $0.32,per share) for the same period in ...
Cached Biology Technology:Climate change: When it rains it (really) pours 2SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 2SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 3SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 4SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 5SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 6SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 7SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 8SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 9ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 2ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 3ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 4ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 5ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 6ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results 7
Selective media for Salmonella...
... can be used as a fully functional, ... Software provides the means to record and ... These data can then be copied and ... Microsoft Excel or Lotus 123, or into ...
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
... Yeast Oligo Microarray Kit (V2), 2 ... simultaneously characterize expression of many thousands ... activity during important biological processes. Each ... 6,256 known ORFs from the S288C ...
Biology Products: