Navigation Links
University of Minnesota engineering researcher finds new way to fight antibiotic-resistant bacteria
Date:11/22/2010

New findings by civil engineering researchers in the University of Minnesota's College of Science and Engineering shows that treating municipal wastewater solids at higher temperatures may be an effective tool in the fight against antibiotic-resistant bacteria.

Heating the solid waste to 130 degrees Fahrenheit (55 degrees Celsius) was particularly effective in eliminating the genes that confer antibiotic resistance. These genes are used by bacteria to become resistant to multiple antibiotics, which are then known as "superbacteria" or "superbugs."

The research paper was recently published in Environmental Science & Technology, a journal of the American Chemical Society and highlighted in the society's weekly magazine Chemical & Engineering News.

Antibiotics are used to treat numerous bacterial infections, but the ever-increasing presence of antibiotic-resistant bacteria has raised substantial concern about the future effectiveness of antibiotics.

"The current scientific paradigm is that antibiotic resistance is primarily caused by antibiotic use, which has led to initiatives to restrict antibiotic prescriptions and curtail antibiotic use in agriculture," said civil engineering associate professor Timothy LaPara, an expert in both wastewater treatment and microbiology who led the new University of Minnesota study. "Our research is one of the first studies that considers a different approach to thwarting the spread of antibiotic resistance by looking at the treatment of municipal wastewater solids."

Antibiotic resistant bacteria develop in the gastrointestinal tracts of people taking antibiotics. These bacteria are then shed during defecation, which is collected by the existing sewer infrastructure and passed through a municipal wastewater treatment facility. The majority of wastewater treatment plants incubate the solid waste, called sludge, in a "digester" that decomposes organic materials. Digesters are often operated at 95 to 98 degrees Fahrenheit (35 to 37 degrees Celsius).

"Many digesters are operated at our body temperature, which is perfect for resistant bacteria to survive and maybe even grow," LaPara said.

Lab research by LaPara and his graduate student David Diehl shows that anaerobic digestion of municipal wastewater solids at high temperatures (as high as 130 degrees Fahrenheit or 55 degrees Celsius) is capable of destroying up to 99.9 percent of various genes that confer resistance in bacteria. In contrast, conventional anaerobic digestion (operated at 95 to 98 degrees Fahrenheit or about 37 degrees Celsius) demonstrated only a slight ability to eliminate the same set of genes.

"Our latest research suggests that high temperature anaerobic digestion offers a novel approach to slow the proliferation of antibiotic resistance." LaPara said. "This new method could be used in combination with other actions, like limiting the use of antibiotics, to extend the lifespan of these precious drugs."

LaPara also pointed out that raising the temperature of anaerobic digestion at wastewater treatment plants is not cost-prohibitive because the digesting bacteria produce methane gas that can be used to heat the reactor.


'/>"/>

Contact: Rhonda Zurn
rzurn@umn.edu
612-626-7959
University of Minnesota
Source:Eurekalert

Related biology news :

1. Hybrid tugboat cuts emissions, University of California, Riverside study shows
2. Hebrew University research carries cautionary warning for future stem cell applications
3. 11 University of Miami grad students receive recognition in marine and atmospheric science
4. Technology developed at Queens University allows medical workers to better assess brain injuries
5. Tufts University chemist earns prestigious award for promising research on drug development
6. Karl Deisseroth of Stanford University receives HFSP Nakasone Award
7. Michigan State University Federal Credit Union Deploys DigitalPersona Pro to Simplify Password Management and Strengthen Security
8. Columbia University Medical Center announces 2010 Katz Prizes in cardiovascular research
9. University of Illinois researchers discover potential new virus in switchgrass
10. Texas A&M University becomes key player in global study to save Earths endangered species
11. Falling in love more scientific than you think, according to Syracuse University professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. ... a business relationship that includes integrating Syngrafii,s patented ... branch project. This collaboration will result in greater ... the credit union, while maintaining existing document workflow ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
(Date:6/2/2016)... 2016 The Department of Transport Management ... 44 million US Dollar project, for the , ... Personalization, Enrolment, and IT Infrastructure , to ... and implementation of Identity Management Solutions. Numerous renowned international vendors ... Decatur was selected for the most compliant and ...
(Date:6/2/2016)... June 2, 2016 Perimeter Surveillance ... Unmanned Systems, Physical Infrastructure, Support & Other Service  ... visiongain offers comprehensive analysis of the global ... will generate revenues of $17.98 billion in 2016. ... Inc, a leader in software and hardware technologies for ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Liquid Biotech ... funding of a Sponsored Research Agreement with The ... cells (CTCs) from cancer patients.  The funding will ... levels correlate with clinical outcomes in cancer patients ... will then be employed to support the design ...
(Date:6/24/2016)... ... ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension of 8.5 ... end machines that use the more unconventional z-dimension of 20mm. Z-dimension or ... the cuvette holder. , FireflySci has developed several Agilent flow cell product lines ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
Breaking Biology Technology: