Navigation Links
University of Minnesota discovery suggests a new way to prevent HIV from infecting human cells
Date:12/22/2010

They envision that future studies will involve a more refined mapping of the physical interactions between Vif and APOBEC3 proteins, investigation of the potential for HIV to resist stabilizing changes in APOBEC3 proteins, and screens for drug-like compounds that help the cellular APOBECs destroy HIV.

John Albin, a student in the Combined MD-PhD Training Program at the University of Minnesota Medical School, and is completing a thesis under the guidance of his advisor, Reuben Harris, through the Microbiology, Immunology & Cancer Biology PhD program. His studies in the Harris lab focus on the potential of APOBEC proteins to impact HIV evolution and pathogenesis.

This latest finding builds on a body of research from Harris's lab about the relationship between HIV and APOBEC proteins. In 2003 and 2004, Harris helped discover that the APOBEC proteins have the ability to counteract HIV infection.

Harris, who won a 2009 challenge grant from the Bill & Melinda Gates Foundation to explore ways to block HIV and APOBEC3 interaction, has been studying mechanisms of mutation for nearly 20 years, first as a doctoral student at the University of Alberta, then as a post-doctoral fellow at the Laboratory of Molecular Biology in Cambridge, England, and for the past seven years as an NIH supported principal investigator at the University of Minnesota. His laboratory focuses on how mutations can be harnessed to destroy pathogens.


'/>"/>

Contact: John Albin
albi0028@umn.edu
612-624-0459
University of Minnesota
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rice University establishes National Corrosion Center
2. Case Western Reserve University researchers track Chernobyl fallout
3. Case Western Reserve University project ties soil conservation and river management together
4. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
5. NIH selects Case Western Reserve University to participate in National Childrens Study
6. US Senate confirms Clemson University engineering Dean Esin Gulari to National Science Board
7. University professor stresses links between US Navy sonar and whale strandings
8. Scent on demand: Hebrew University scientists enhance the scent of flowers
9. University success at national engineering awards
10. University of Leicester professor adds new perspective to rainforest debate
11. Providing toilets, safe water is top route to reducing world poverty: UN University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... researchers at the National Institute of Standards and ... their work more effectively, they often prove that ... was the case recently for M. Lorna De ... the growing specialization of glycomics. Glycomics is the ... glycans that are attached to proteins and lipids ...
(Date:7/11/2014)... Ume University, Sweden, have explored two different ways ... sequence leading to the formation of oxygen molecules ... in the scientific journal Nature Communications . ... day synthetic catalysts for water oxidation, which are ... the direct storage of solar energy in fuels ...
(Date:7/11/2014)... normal circumstances, astrocytes participate in normal physiological ... exhibit therapeutic and repairing effects on brain ... found that nerve cells differentiated from adipose-derived ... viability, which produces influences on subsequent studies ... Hospital, Hebei United University, China demonstrated that ...
Breaking Biology News(10 mins):Molecular snapshots of oxygen formation in photosynthesis 2
... Pathogens , Francisella tularensis , the cause of ... is considered a potential biological weapon because it is readily ... in humans. While a live attenuated vaccine strain has ... to understand the basis for its attenuated virulence. In ...
... Universitt Mnchen (TUM) under Prof. Peter Schieberle and at the ... edible fats and oils: Lard, butterfat, rapeseed oil and olive ... ate 500 grams of low-fat yoghurt enriched with one of ... supplement to their normal diet. "Olive oil had the ...
... series across both genders continue to remain alarmingly low ... patient education and increased public vaccine financing programs are ... Texas Medical Branch (UTMB). The researchers report ... published in Cancer, Human Vaccines & Immunotherapeutics ...
Cached Biology News:News tips from the journal mBio®, volume 4, issue 1 2Olive oil makes you feel full 2HPV vaccine trends point to failures in patient education, vaccine programs 2
(Date:7/10/2014)... Mass. (PRWEB) July 10, 2014 Terascala, ... today announced that Alan Swahn, a former vice president ... executive team as vice president of marketing. Terascala’s software ... Dell and NetApp create the highest performance and most ... been appointed to guide Terascala’s channel expansion and broaden ...
(Date:7/10/2014)... Montreal, QC (PRWEB) July 10, 2014 ... comfort and convenience. This rejuvenating device now comes with a ... that develops over time. , The new cup is thinner ... This design works to target rough, thin and uneven surfaces ... original firm cup for a stimulating treatment on areas such ...
(Date:7/10/2014)... 10, 2014  Kainos Capital, a firm specializing in ... that it has acquired the Slim-Fast brand from Unilever. ... Terms of the transaction were not disclosed. ... business that markets ready-to-drink shakes, powders, bars and snacks ... and in the United Kingdom ...
(Date:7/10/2014)... D.C., April 15, 2014 -- According to the ... to nuclear security comes from terrorists acquiring sufficient ... to construct a crude nuclear explosive device. The ... nuclear trafficking have involved gram-level quantities, which can ... , According to a new study appearing this ...
Breaking Biology Technology:Terascala Expands Executive Team 2Terascala Expands Executive Team 3Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2Kainos Capital Acquires Slim-Fast From Unilever 2Sensitive detection method may help impede illicit nuclear trafficking 2
... executives hold high expectations that information technology will reduce ... however.  Earley & Associates, the nation,s foremost information management ... series titled Digitization of the Healthcare Industry ... on Wednesday, May 4 from 1-2 p.m. ...
... 3, 2011 Talecris Biotherapeutics Holdings Corp. (NASDAQ: ... Chapel Hill, N.C., where four proposals were submitted to, and ... the company,s Board of Directors to hold office for a ... and until their successors are elected and qualified. The three ...
... Inc. (Nasdaq: NVAX ) will report financial results ... 2011, before the U.S. financial markets open.  The announcement will ... Stanley C. Erck, President and Chief Executive Officer, and other ... The webcast and conference call will be available ...
Cached Biology Technology:Earley & Associates Offers Two-Part Webinar Series on Challenges and Solutions to Digitization in Healthcare 2Earley & Associates Offers Two-Part Webinar Series on Challenges and Solutions to Digitization in Healthcare 3Talecris Biotherapeutics Announces Results of Annual Stockholders' Meeting 2
The DNA DipStick Kit is ideal for estimating nucleic acid concentrations and approximate yields. Works with ss- and ds-DNA, RNA, and oligonucleotides at concentrations as low as 0.1 ng/l....
Request Info...
... ideal for both radioactive and nonradioactive labeling ... Provides five pre-mixed nucleotide solutions for flexibility ... 8 cpm/g control DNA using [-32P]-dCTP ... performance of the system Labels 1 ...
ABI 432 Resins • Gln(Trt) Peptide Synthesis Column...
Biology Products: