Navigation Links
University of Maryland receives $1.9M from NSF for investigations of biomolecular structure
Date:8/24/2010

COLLEGE PARK, Md. - The University of Maryland has received a $1.9 million grant from the National Science Foundation to acquire a superconducting 800 MHz Nuclear Magnetic Resonance (NMR) spectrometer that will help scientists and engineers to solve complex problems in biology and medicine. The instrument will be the highest field NMR spectrometer to be located on the College Park campus and will enable scientists to investigate the three-dimensional structure of biological molecules and study their interactions with a degree of resolution and sensitivity not previously possible.

Kwaku Dayie, associate professor of chemistry and biochemistry, is the principal investigator on the grant, and will utilize this technology to advance his research on the biophysics of RNAs (ribonucleic acids). RNAs are biological molecules that are critical to life, and that play a role in many diseases for which effective treatments are still sought.

"RNAs do a lot more in cells than we have given them credit for," explains Dayie, who is associated with the university's Center for Biomolecular Structure and Organization (CBSO). "They can speed up chemical reactions by up to 100 billion fold without the need of protein enzymes, and they can regulate gene expression just as proteins can. Being able to map out their 3D architecture using this high field NMR technology means we'll be able to see more clearly how we could target them for drug discovery and delivery."

Two other faculty members of the Department of Chemistry and Biochemistry and the CBSO, Professor David Fushman and Assistant Professor Vitali Tugarinov, and one in the Department of Chemical and Biomolecular Engineering, Assistant Professor Ganesh Sriram, will be co-principal investigators. Both Fushman and Tugarinov are experts in the study of protein structure and dynamics using NMR methods, and they will now be able decipher interactions between important biological macromolecules that they c
'/>"/>

Contact: Kelly Blake
kellyb@umd.edu
301-405-8203
University of Maryland
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rice University establishes National Corrosion Center
2. Case Western Reserve University researchers track Chernobyl fallout
3. Case Western Reserve University project ties soil conservation and river management together
4. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
5. NIH selects Case Western Reserve University to participate in National Childrens Study
6. US Senate confirms Clemson University engineering Dean Esin Gulari to National Science Board
7. University professor stresses links between US Navy sonar and whale strandings
8. Scent on demand: Hebrew University scientists enhance the scent of flowers
9. University success at national engineering awards
10. University of Leicester professor adds new perspective to rainforest debate
11. Providing toilets, safe water is top route to reducing world poverty: UN University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... help reduce or reverse soil subsidence and reduce ... Sacramento-San Joaquin River Delta by Dartmouth College researchers ... one of the first to continually measure the ... cycle through wetlands, appears in the journal by ... Worldwide, agricultural drainage of organic soils has resulted ...
(Date:10/30/2014)... This news release is available in German . ... we as individuals prompt our fellow humans to behave ... to social dilemmas in game theory. Previous studies assumed ... large groups. Nonetheless, scientists from the Max Planck Institute ... us can exert an influence on the cooperative behaviour ...
(Date:10/30/2014)... State University researchers have developed a suite of technologies ... and humans, which has applications in everything from search ... , "We,ve developed a platform for computer-mediated communication between ... avenues for interpreting dogs, behavioral signals and sending them ... Roberts, an assistant professor of computer science at NC ...
Breaking Biology News(10 mins):Dartmouth study finds restoring wetlands can lessen soil sinkage, greenhouse gas emissions 2Together we are strong -- or insufferable 2Together we are strong -- or insufferable 3Together we are strong -- or insufferable 4New tech aims to improve communication between dogs and humans 2
... German . , , "Watch out, it,ll hurt for a ... they hear those words from their doctor. And, as soon as ... very clearly. "After such an experience it is enough to simply ... pain memory", knows Prof. Dr. Thomas Weiss from the Friedrich-Schiller-University Jena. ...
... toads, salamanders, and newtsare disappearing worldwide, but the stream ... This region is home to the largest diversity of ... here), and scientists want to understand what contributes to ... in the March 29, 2010 issue of the ...
... Bionic Vision Australia (BVA) today unveils their wide-view ... implanted into Australia,s first recipient of the technology. ... at the University of New South Wales and unveiled ... University of Melbourne, will deliver improved quality of life ...
Cached Biology News:Do words hurt? 2Young salamanders' movement over land helps stabilize populations 2Young salamanders' movement over land helps stabilize populations 3Bionic Vision Australia puts bionic eye in sight 2
(Date:10/30/2014)... October 30, 2014 SoundConnect ... provider, offers Office 365 end users the key ... complete phone system by adding voice enablement and ... includes Lync Online, a communication tool that includes ... With hosted voice, O365 becomes a comprehensive unified ...
(Date:10/30/2014)... James Sherley says he has been working ... cell technology since his days as a principal investigator at ... late 1990’s. Sherley founded the ASCTC as a new ... the intellectual property developed in Sherley’s research over the years ... of Technology (MIT), and more recently as a senior scientist ...
(Date:10/30/2014)... October 30, 2014 Whitehouse Laboratories has ... ICH Stability Testing and Package Test Capacity. Responding to ... on a dramatic increase in environmental chamber storage space ... storage and aging samples to be securely held on ... major capital expenditure has already taken place with the ...
(Date:10/30/2014)... October 30, 2014 Grace Century portfolio project, ... A. Manganello, Chairman of the Board, to the National ... The appointment was made by the Ministry of Health on ... 2014. , More than a year after Bahamian ... , Prime Minister Perry Christie said the government has completed ...
Breaking Biology Technology:SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 2SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 3Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 2Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 3Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 4Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 2Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 3Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3
... PARI Respiratory Equipment,s,breath-enhanced nebulizer, the PARI ... L.P.,s new COPD medication, Perforomist Inhalation Solution,that ... subsidiary of Mylan Inc.,(NYSE: MYL ). ... indicated for,long-term, twice-daily maintenance treatment of bronchoconstriction ...
... WASHINGTON, D.C., October 9 Bavarian Nordic,the Danish-based ... of Health and Human Services (HHS) to,invoice an ... the recent,contract (RFP-3)* to manufacture and deliver 20 ... HHS approved the advance payment because Bavarian Nordic ...
... Patient-Safety ... Technology,eRx NOW(TM) Functionality Expanded to ... Physician Portal Lab Order and Results Capabilities, LYNDHURST, N.J. and ... leading provider of,diagnostic testing, information and services and a leading developer of,healthcare ...
Cached Biology Technology:PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday 2PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday 3PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday 4Bavarian Nordic Receives $50 Million Advance Payment from HHS for Fulfilling Contract Milestones 2Bavarian Nordic Receives $50 Million Advance Payment from HHS for Fulfilling Contract Milestones 3Quest Diagnostics Joins National ePrescribing Patient Safety Initiative (NEPSI) 2Quest Diagnostics Joins National ePrescribing Patient Safety Initiative (NEPSI) 3Quest Diagnostics Joins National ePrescribing Patient Safety Initiative (NEPSI) 4Quest Diagnostics Joins National ePrescribing Patient Safety Initiative (NEPSI) 5
... is commonly used as a fusion partner ... The GSTTag sequence has been reported to ... the solubility of its fusion partners. When ... GSTTag fusion proteins can be purified with ...
... The LX80L is an extension of Parkers ... maintaining a compact cross-section. LX80L bolt hole patterns ... mount MX80 units and all accessory brackets to ... stage with travel to 750 mm , Accelerations ...
... PEP-005 is a synthetic peptide whose sequence is from the C-terminal end ... acid sequence extends from amino acids 429 to 448 of RAR*. ... - S - V - S - P - S - S ... - S - Q - S - P - L - L ...
... Rat Neural Stem Cell Kit with ... cells (NCSs) complete with optimized base medium ... and plate these unique cells generated from ... you need for a tissue-like mixture of ...
Biology Products: