Navigation Links
University of Maryland partnership receives $7.9M from NIH for superconducting research magnet
Date:8/11/2010

al for studying large proteins," explains Fushman, an expert in protein structure and dynamics who is associated with the university's Center for Biomolecular Structure and Organization (CBSO). "This will allow us to move into structural and biophysical studies of protein assemblies that include more than 1000 amino acids, as well as large complexes of proteins and nucleic acids. We can begin to decipher interactions between important biological macromolecules that we could not study before. This is huge!"

Fushman conducts biochemical and biophysical studies to understand the molecular basis of how proteins are marked for degradation by a signaling protein called ubiquitin. Once a protein is tagged by ubiquitin chains, it is then disposed of by a multimolecular complex called the proteasome. "The proteasome is like a big molecular shredder which grinds up proteins that are no longer needed or which have become misfolded or abnormal," Fushman explains. "It controls the cell life cycle, and we know that if it isn't functioning properly, it could lead to the development of cancers, or neurological diseases like Parkinson's, Alzheimer's, or Huntington's, or problems with the immune response."

Kwaku Dayie, associate professor, and Vitali Tugarinov, assistant professor, both in the Department of Chemistry and Biochemistry and members of CBSO, will also be key users of the new technology. Both have been leaders in the development of NMR methods that allow and facilitate studies of large macromolecules. Jonathan Dinman and Anne Simon, both professors of cell biology and molecular genetics and experts in the study of viruses, will also utilize the spectrometer to advance their research.

"The capabilities of this ultra high field/high frequency NMR will create unique opportunities for life sciences researchers in Maryland," says Norma Allewell, vice president for research and professor of cell biology and molecular genetics at the University
'/>"/>

Contact: Kelly Blake
kellyb@umd.edu
University of Maryland
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Ben-Gurion University of the Negev professor awarded the 2010 Elkeles Prize for Cancer Research
2. Hebrew University researchers identify gene related to chronic pain
3. Scientists at University of Colorado Anschutz Medical Campus discover new fat cell
4. NJIT professor receives Fulbright to study at University of Salerno
5. University of Hawaii completes 3-year investigation of military munitions sea disposal site
6. Ben-Gurion University of the Negev researchers identify risks of hypertension in young adults
7. University of Washington professors lifetime efforts receive international recognition
8. Kids could get more whole grains from after-school snacks, University of Minnesota study finds
9. Tulane University will receive $11.2 million to lead international malaria research center
10. University of Manchester academics at international conference on geographic chemicals
11. University receives $19 million to monitor carbon storage project
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... from the Max Planck Institute for Medical Research in ... understanding photosynthesis, the process by which the Earth first ... and which is therefore crucial for all higher forms ... the first direct visualization of a crucial event in ... specific protein complex, photosystem II, splits water into hydrogen ...
(Date:7/11/2014)... of kidney injury related to the use of hydroxyethyl ... HES molecules, according to a report in Anesthesia ... Research Society (IARS). , The "total mass of HES ... human renal proximal tubule cells (PTCs), concludes the laboratory ... Hospital Wrzburg, Austria. Other factorssuch as differences in ...
(Date:7/11/2014)... is evidence that under the normal circumstances, ... development, maintain neuronal environment, and exhibit therapeutic ... neurodegenerative disease. Previous studies have found that ... after chemical induction have reduced viability, which ... Prof. Xiaodong Yuan, Kailuan General Hospital, Hebei ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2
... new study has revealed that mother birds can provide ... sired with their non-social partner (known as extra-pair offspring). ... birds commonly mate with males other than their social ... interloper,s ,extra pair, offspring often outperform their half brothers ...
... Technology for the first time have shown the earliest ... formation of bones, teeth and sea shells. ... capture a three-dimensional image of the nanoparticles that form ... greater understanding of the formation of bones, teeth and ...
... in US women of childbearing age, and is common in ... in the vagina is disrupted and replaced by an overgrowth ... increased risk for a variety of complications, such as preterm ... be prevented. Vitamin D may play a role in BV ...
Cached Biology News:Mothers give interloper's offspring a head start in life 2Mothers give interloper's offspring a head start in life 3Focus on the formation of bones, teeth and shells 2Vitamin D insufficiency linked to bacterial vaginosis in pregnant women 2
(Date:7/11/2014)... (PRWEB) July 11, 2014 Cayenne ... company specializing in the soft tissue reconstruction segment, ... Anchor System for surgeries involving the shoulder and ... through a novel, inserter-controlled deployment method. The unique ... partial deployment, anchor pull-out, or anchor displacement (also ...
(Date:7/10/2014)... Mass. (PRWEB) July 10, 2014 Terascala, ... today announced that Alan Swahn, a former vice president ... executive team as vice president of marketing. Terascala’s software ... Dell and NetApp create the highest performance and most ... been appointed to guide Terascala’s channel expansion and broaden ...
(Date:7/10/2014)... 2014 Senior supply chain management executives ... addressed the challenges of “Reducing Cost, Lead Time, & ... strategic sourcing. Describing the partnership of the Bio Supply ... Management Institute ( SCMI) of the University of ... at the Kroc Institute of Peace and Justice in ...
(Date:7/10/2014)... July 10, 2014 Research and Markets ... the "International Photonic Integrated Circuit (Monolithic Integration, ... 2019" report to their offering. ... concept of photonic integration traces its roots in ... promise of photonic integration went unexplored and unfulfilled ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Terascala Expands Executive Team 2Terascala Expands Executive Team 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2
... (Pink Sheets: BSTC.PK) today announced that it sold,200,000 ... private placement,offering to an investment fund, at a ... to the Company of $2,100,000., About BioSpecifics ... biopharmaceutical company that has,developed and licensed injectable collagenase ...
... is seeking nominations for the Third Annual Greater ... March 18, 2008. Those,interested in nominating a company ... The four award categories are: Entrepreneurial, Best ... Award. Nominators will,be asked to submit documentation and ...
... multiplexing module, SANTA ROSA, Calif., Jan. 14 ... provider of optical components for industrial,applications, is to ... technology. The compact LED combining module, which utilizes,proprietary ... medical instrumentation. The ZoroLight LED module will be,on ...
Cached Biology Technology:Bookham to Enter Biomedical Illumination Market 2Bookham to Enter Biomedical Illumination Market 3
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
... provide fast and reliable automation for ... drug development laboratories. Staccato Mini-Workstations offer ... automate basic liquid handling and material ... with either Caliper's time proven CLARA™ ...
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
... Fermentation System to achieve high ... and maximum information output 4 ... precision with small-scale requirements provides users ... with E.coli, Pichia pastoris, yeast, fungi ...
Biology Products: