Navigation Links
University of Maryland School of Medicine study identifies genes associated with binge drinking
Date:2/28/2011

king followed by withdrawal. But binge drinking carries the same serious health risks as other types of excessive drinking: Cancer, heart disease and, most notably, the serious public health issue of vehicle accidents."

In the study, Dr. June and senior author Laure Aurelian, Ph.D., professor of pharmacology and experimental therapeutics and microbiology and immunology at the University of Maryland School of Medicine, examined the effect of alcohol on the GABA receptor and TLR4. GABA receptors are a class of receptors in the brain that react to the neurotransmitter GABA and act as inhibitory receptors, calming down or inhibiting the activity of neurons in the brain. GABA receptors react to alcohol, giving drinkers a calm and euphoric feeling and reinforcing excessive drinking behavior. Dr. June has long been interested in the role GABA receptors play in alcoholic drinking. This is the first scientific study to document GABA receptors' key involvement in binge drinking specifically, though scientists already believed that the receptors had a role in excessive drinking in general.

"The University of Maryland School of Medicine employs a dual approach to addiction and substance abuse, providing treatment for those struggling with addiction through its Division of Alcohol and Drug Abuse, as well as invaluable scientific research into the biological roots of addiction and alcoholism," says E. Albert Reece, M.D., Ph.D., M.B.A., vice president for medical affairs for the University of Maryland and the John Z. and Akiko K. Bowers Distinguished Professor and dean of the School of Medicine. "We hope that basic science discoveries such as this one will translate rapidly into better treatments to improve the lives and health of those struggling with alcohol, and address the serious public health issue of addiction and substance abuse."

One of the study's most novel findings concerns TLR4's important role in binge drinking. Science has traditionally co
'/>"/>

Contact: Karen Robinson
karobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Rice University establishes National Corrosion Center
2. Case Western Reserve University researchers track Chernobyl fallout
3. Case Western Reserve University project ties soil conservation and river management together
4. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
5. NIH selects Case Western Reserve University to participate in National Childrens Study
6. US Senate confirms Clemson University engineering Dean Esin Gulari to National Science Board
7. University professor stresses links between US Navy sonar and whale strandings
8. Scent on demand: Hebrew University scientists enhance the scent of flowers
9. University success at national engineering awards
10. University of Leicester professor adds new perspective to rainforest debate
11. Providing toilets, safe water is top route to reducing world poverty: UN University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Mineral Research awarded Michael F. Holick, PhD, MD, of ... Louis V. Avioli Award. Holick, a professor of medicine, ... revolutionizing the understanding of vitamin D and its role ... member of the American Society for Bone and Mineral ... basic research. It is named for ASBMR,s first president ...
(Date:7/11/2014)... Cell scientists have set a "mouse TRAP" to capture ... a recent study published in the Journal of ... a technique called TRAP to extract cellular and genetic ... by scientists at the Rockefeller Institute for Medical Research ... the protein-making machinery, or ribosomes, of the cell type ...
(Date:7/11/2014)... Researchers from Salk Institute for Biological Studies, BGI, ... the safety and reliability of the existing targeted ... method, TALEN-HDAdV, which could significantly increased gene-correction efficiency ... study published online in Cell Stell Cell ... cell-based gene therapy. , The combination of stem ...
Breaking Biology News(10 mins):BUSM's Michael F. Holick receives American Society for Bone and Mineral Research award 2A new genome editing method brings the possibility of gene therapies closer to reality 2
... (September 25, 2007) Stem cell therapy for cardiac ... media will be the focus of the keynote addresses ... Treatment of Cardiovascular Disease conference. Conducted by Cedars-Sinai Medical ... and 5, the conference is co-sponsored by the California ...
... For several months last spring, the Vanderbilt greenhouse held ... than are known to exist in the wild., This ... by Jennifer Ellis, a doctoral student in the biological ... E. McCauley., The species is called the giant whorled ...
... Cryptochromes, which fulfill the molecular requirements for sensing the ... neurons of migratory birds (Mouritsen et al., PNAS, 2004). ... brain are active when the birds use their magnetic ... and a forebrain region (Cluster N; Mouritsen et al., ...
Cached Biology News:Cardiologists and heart surgeons meet for 'Controversies and Advances' conference 2Cardiologists and heart surgeons meet for 'Controversies and Advances' conference 3Student study bolsters case for adding a rare sunflower to the endangered species list 2
(Date:7/10/2014)... journal PNAS (Proceedings of the National Academy of ... sleep deprivation have a significant effect on our metabolism. ... best time of day to test for diseases such ... effectively. , Researchers from the University of Surrey and ... between sleep deprivation, body clock disruption and metabolism, and ...
(Date:7/10/2014)... our laptops and electric vehicles could store more energy ... help of a sponge-like silicon material. , Researchers ... used in one of the battery,s electrodes, as silicon ... of graphite. A paper describing the material,s performance as ... Nature Communications . , "Silicon has long been sought ...
(Date:7/10/2014)... the University of Illinois at Urbana-Champaign provides new ... of spin and heat at the nanoscale, and ... for data storage and information processing. , ... momentum. In a typical charge current, electrons, spin-angular-momentum ... explained David Cahill, a professor of materials science ...
(Date:1/15/2014)... , "The interface is the device," Nobel laureate ... properties to be found at the junctures where ... world of nanotechnology, the interfaces between layers of ... in such high-tech favorites as spintronics, high-temperature superconductors, ...
Breaking Biology Technology:Time of day crucial to accurately test for diseases, new research finds 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3University of Illinois study advances limits for ultrafast nano-devices 2A deeper look at interfaces 2
... launched interactive, personalized services for Milwaukee drivers through ... announced Thursday. Traffic.com will provide area commuters with ... roadway traffic conditions including congestion levels, incidents, travel ... news release. , ,Data for the site will ...
... Madison, Wis. - While human stem cells offer potential ... the more immediate benefit from research into such cells will ... an area that for many years has been steeped in ... research since disease works within the context of cells. , ...
... - Healthcare professionals will have the opportunity hear about ... profession at the Wisconsin Dairyland HIMSS Fall Technology Conference ... the Radisson hotel in La Crosse, will be split into ... events such as a golf outing and a riverboat cruise, ...
Cached Biology Technology:Human stem cells called great opportunity for drug discovery 2Human stem cells called great opportunity for drug discovery 3Conference will review healthcare IT 2
... is a major step forward in ... handling system - with one universal ... modules. All five single channel and ... one handle. The lightweight handle is ...
alpha-N-Catenin Antibody Shipping Temperature: HOT Storage Temperature: -20C...
... EC3 Darkroom is designed for imaging of ... EC3 systems offer direct control for users ... settings by hand , A range of ... system for all fluorescent and chemiluminescent applications ...
... is designed for multiple user laboratories for ... TLC applications. The MultiDoc-It is available without ... provides a darkroom environment and protects the ... image capture and enhancement , The ...
Biology Products: