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University of Maryland School of Medicine receives $7.9 million grant for 'super' research magnet
Date:8/11/2010

rector of the University of Maryland Marlene and Stewart Greenebaum Cancer Center, and professor of medicine and director of the Program in Oncology at the University of Maryland School of Medicine.

"We will be the only academic facility in the country to have this powerful magnet," says E. Albert Reece, M.D., Ph.D., M.B.A., vice president of medical affairs at the University of Maryland and dean of the University of Maryland School of Medicine. "This technology is a testament to our status as a world-class research institution. The magnet will be a critical tool in our mission to use the latest in cutting-edge technologies in our labs to bring lifesaving new treatments to patients in the clinic."

The 22.3 Tesla magnet is so powerful that it could lift 50 cars. The equipment will be housed in the UMB NMR core facility, located at the University of Maryland School of Medicine, and will be used by researchers from all three campuses as well as from institutions throughout the Mid-Atlantic region.

The instrument initially will have 35 users including 10 major core users and will operate 24 hours a day, seven days a week, according to Dr. Weber.

"Being able to observe molecules at the atomic-level eliminates a great deal of guessing when you're conducting complicated molecular experiments. We will have a much better ability to look at larger molecules and protein complexes with this powerful magnet it's like working in a room with the lights turned on," Dr. Weber says.

Dr. Weber's laboratory is developing small-molecule inhibitors geared to a family of calcium-binding proteins called S100 proteins, including one that currently is being tested in a clinical study at the cancer center as a possible treatment for melanoma. Other cancer center researchers are studying ways to help repair the DNA in cells that have been damaged by cancer.


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Contact: Karen E. Warmkessel
kwarmkessel@umm.edu
410-328-8919
University of Maryland Medical Center
Source:Eurekalert

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