Navigation Links
University of Arizona scientist shares in discovery of microbe filaments' power
Date:4/18/2008

Researchers from The University of Arizona and Columbia University have discovered that tiny filaments on bacteria can bundle together and pull with forces far stronger than experts had previously thought possible.

The team of researchers, including Magdalene Maggie So, a member of the BIO5 Institute and the department of immunobiology in the UA College of Medicine, studied Type IV pili or filaments on the surface of Neisseria gonorrhoeae, the bacterium that causes the infectious disease gonorrhea. The research results help them understand the role that Type IV pili play in initiating a variety of infectious diseases including tuberculosis and how retracting pili allow bacteria to crawl and to exchange genes with each other.

When a bundle of Type IV pili retracts, it pulls with a force in the nanoNewton range, which is 10 times the force of a single retracting filament. The study demonstrates the power and cooperative nature of the nanomotors that cause Type IV pili to retract.

The motor that causes these filaments to pull is one of the strongest nanomotors known in biology, So said.

In previous studies, the same group of investigators measured single filament retraction forces in the 50 to 100 picoNewton range. This force allows the bacterium to move an object 10,000 times its own body weight. Retraction forces from a bundle are roughly 10 times higher, allowing the bacterium to move objects 100,000 times its body weight.

Pilus retraction forces are an important factor in how N. gonorrhoeae starts an infection. So, who has studied these microbes for more than 20 years, says N. gonorrhoeae communicates with a human cell by pulling on it. These pulling forces perturb the normal circuitry of the cell. As a result, the infected cell is fooled into lowering its defenses against the infecting microbe.

So said that the team of investigators came up with a new method to measure the tremendous forces applied by
'/>"/>

Contact: Deborah Daun
ddaun@email.arizona.edu
520-626-2059
University of Arizona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Flowers fragrance diminished by air pollution, University of Virginia study indicates
2. Pitt and University of Chicago researchers uncover process behind heart muscle contraction
3. Yale Universitys Strobel recognized for work on RNA
4. Womens health-related scientific findings presented by University of Pittsburgh researchers
5. Researchers at Stockholm University awarded the Descartes prize
6. Policing cells demand ID to tell friend from foe, say University of Pennsylvania cell engineers
7. Antarcticas coldest, darkest season draws Montana State University researchers
8. University of Colorado at Boulder awarded $1 million for biofuels research
9. Viruses evolve to play by host rules, according to University of Pennsylvania researchers
10. New whitepaper offers options for university implementation of NIH policy
11. Electronic structure of DNA revealed for 1st time by Hebrew University and collaborating researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... WINSTON-SALEM, N.C. , Dec. 9, 2014  Wake Forest ... medical education building for its School of Medicine. Funding ... a larger capital campaign that will be publicly launched ... will be located in the former 60 series R.J. ... Forest Innovation Quarter. Construction will begin immediately with plans ...
(Date:12/10/2014)... DUBLIN , Dec. 08, 2014 Research ... announced the addition of the "Biometrics Market ... http://photos.prnewswire.com/prnh/20130307/600769 ... for projects such as rural banking and upgradation ... major trends witnessed in the market. Besides the ...
(Date:12/5/2014)... VIEW, Calif. , Dec. 4, 2014 /PRNewswire/ ... safety has boosted investments in new testing and ... has also given rise to a range of ... by the requirements of Generation Y, which is ... technologies. As a result, product development strategies of ...
Breaking Biology News(10 mins):Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... Laws protecting the critically endangered Sumatran Tiger have failed ... Indonesia, according to a TRAFFIC report launched today. ... whiskers and bones, were on sale in 10 percent ... 28 cities and towns across Sumatra. Outlets included goldsmiths, ...
... of dinosaur unearthed in Mexico is giving scientists fresh insights ... an international research team led by scientists from the Utah ... To date, the dinosaur record from Mexico has been sparse, ... Natural History, Utahs designated natural history museum. The new ...
... The U.S. Department of Homeland,Security (DHS) ... additional,fingerprints from international visitors arriving at San ... part of the,department,s upgrade from two- to ... travel by more accurately and,efficiently establishing and ...
Cached Biology News:Body part by body part, Sumatran tigers are being sold into extinction 2New dinosaur from Mexico offers insights into ancient life on West America 2New dinosaur from Mexico offers insights into ancient life on West America 3New dinosaur from Mexico offers insights into ancient life on West America 4New dinosaur from Mexico offers insights into ancient life on West America 5New dinosaur from Mexico offers insights into ancient life on West America 6DHS Begins Collecting 10 Fingerprints From International Visitors at San Francisco International Airport 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... of Bt Maize on His Farm and Family , ... ... 2008 -- In a new online video released today, South ... experience farming genetically modified Bt maize. Since planting his ...
... July 29 James C. Powell, former,President and ... the,Board of Directors of Nerites Corporation., Under ... dozens of corporate partnerships to commercialize products.,Powell joined ... Product,Development; he helped lead the company,s transition from ...
... BELLEVUE, Wash., July 29 SCOLR Pharma, Inc.,(Amex: ... 2008 financial,results on Thursday, August 7, 2008, at 8:30 ... Pharma, will host a conference call at 11:30,a.m. Eastern, ... parties may participate in the,conference call by dialing +1 ...
Cached Biology Technology:South African Farmers Increase Plantings of Genetically Modified Crops 2South African Farmers Increase Plantings of Genetically Modified Crops 3James C. Powell Joins Nerites Board of Directors 2SCOLR Pharma, Inc. Schedules Second Quarter 2008 Financial Results Conference Call for August 7, 2008 at 11:30 A.M. Eastern 2
...
Troponin I Immunogen: Full length native protein (purified) (Human). Storage: -20 C, Avoid Freeze/Thaw Cycles...
...
Microlite 1+ 1x12 Strip assembled, flat bottom; the ideal vessel for low signal luminescent reactions, offering medium binding with enhanced dynamic range, extra high reflectivity and minimal cross t...
Biology Products: