Navigation Links
University of Alberta research working towards treatment for aortic aneurysms in the abdomen
Date:12/20/2012

onsible for reducing the elasticity of the artery, which means it can expand to let blood through, but it doesn't snap back to its original form.

From this discovery, the group decided to treat these double knockouts with MMP inhibitors and they were able to save the models from deadly aneurysm.

"If you detect aneurysms at a very early stage, when it's still small bulging in the abdomen, you can put the patient on MMP inhibitors and control the expansion," said Kassiri. "Whereas if you don't, [the aneurysm is] going to expand and may even rupture."

MMP inhibitors could be a good treatment, for now, as many are already approved drugs, such as doxycyclin). But the research group's goal is to develop a targeted therapy to enrich the swollen aorta with TIMP3.

"What we would want to do in the long term is to deliver TIMP3 locally," said Kassiri. "That's a challenging task considering the location of the aorta behind the abdominal area."


'/>"/>

Contact: Quinn Phillips
quinn.phillips@ualberta.ca
780-248-2048
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Page: 1 2

Related biology news :

1. University of Houston study shows BP oil spill hurt marshes, but recovery possible
2. University of Alberta led research may have discovered how memories are encoded in our brains
3. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
4. Marshall University study may lead to new treatments for prostate cancer
5. University leads £6 million EU project to tackle obesity
6. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
7. Life expectancy may affect when you get married, divorced, have kids: Queens University study
8. University of Toronto biologists predict extinction for organisms with poor quality genes
9. University of Minnesota invention helps advance reliability of alternative energy
10. Israel names Tel Aviv Universitys Renewable Energy Center a Center of Research Excellence
11. University of Minnesota startup offers game-changing energy solutions that reduce CO2 emissions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... her eggs until they hatched 4.5 years later, according ... open-access journal PLOS ONE by Bruce Robison ... Octopuses typically have a single reproductive period during their ... their fertilized eggs until they hatch. Shallow-water octopuses typically ... but little is known about the brooding of deep-sea ...
(Date:7/30/2014)... two points is a straight line, and now Harvard ... familiar axiom to heart. , Though competition among ... each racing for the chance to fertilize the egg, ... groups that allow them to take a straighter path ... by Heidi Fisher, a post-doctoral student working in the ...
(Date:7/30/2014)... San Antonio Life Sciences Institute (SALSI), a joint venture ... and The University of Texas Health Science Center at ... Initiative Pilot Program. The winners, Emily Boice from UTSA ... receive $25,000 for their project titled, "Novel engineered ferritins ... environment." , Boice and Huang,s research is focused on ...
Breaking Biology News(10 mins):Deep-sea octopus has longest-known egg-brooding period 2When cooperation counts 2When cooperation counts 3
... A survey of bat activity in burned and unburned areas after ... evidence of detrimental effects on bats one year after the fire. ... some species may even benefit from the effects of fire on ... Frick of the University of California, Santa Cruz, will be published ...
... and Boston, MA. Wed. March 6, 2013 New ... and Women,s Hospital, Harvard University, MIT, and Yale University ... cell known as a T helper 17 or ... the development of immune responses. By figuring out how ...
... Scientists at the Salk Institute for Biological Studies have identified ... adapt to various environments, but could also benefit crop production ... in Nature , the findings show that in addition ... epigenomic makeup is as varied as the environments in which ...
Cached Biology News:Bats not bothered by forest fires, study finds 2Circuitry of cells involved in immunity, autoimmune diseases exposed 2Circuitry of cells involved in immunity, autoimmune diseases exposed 3Circuitry of cells involved in immunity, autoimmune diseases exposed 4Circuitry of cells involved in immunity, autoimmune diseases exposed 5Hidden layer of genome unveils how plants may adapt to environments throughout the world 2Hidden layer of genome unveils how plants may adapt to environments throughout the world 3
(Date:7/30/2014)... 2014  Dyadic International, Inc. ("Dyadic") (OTCQX: DYAI), ... proprietary technologies are used to discover, develop, manufacture ... bioenergy, bio-based chemical, biopharmaceutical and industrial enzyme industries, ... as Vice President and Chief Financial Officer. Tom ... information technology operations for Dyadic and will succeed ...
(Date:7/30/2014)... , July 30, 2014  AtheroNova Inc. (OTCBB: ... and development of compounds to safely regress atherosclerotic ... announces that its partner, CardioNova, has accomplished first ... trial with AtheroNova,s lead compound, AHRO-001.  This Phase ... AHRO-001 Phase 1 safety trial completed in February ...
(Date:7/30/2014)... July 30, 2014 Connecticut Center for ... based in East Hartford, Conn., was awarded a Rural ... of a project that will determine the feasibility of ... north-central Connecticut. USDA Rural Development provided $53,000 for CCAT ... the second phase of the feasibility study in fiscal ...
(Date:7/30/2014)... Immunology Summit-2014 will be ... scientists in the field, which includes prominent personalities ... Western Reserve University School of Medicine, USA, who ... “The effects of recombinant human IL-6 and recombinant ... Biragyn, a Senior investigator at National Institute on ...
Breaking Biology Technology:Thomas Dubinski joins Dyadic as Chief Financial Officer 2Thomas Dubinski joins Dyadic as Chief Financial Officer 3Thomas Dubinski joins Dyadic as Chief Financial Officer 4AtheroNova Announces Milestone with Initiation of Phase 1b Clinical Trial of AHRO-001 2AtheroNova Announces Milestone with Initiation of Phase 1b Clinical Trial of AHRO-001 3AtheroNova Announces Milestone with Initiation of Phase 1b Clinical Trial of AHRO-001 4USDA Grant Funds Second Phase of Bio-Energy Research Community Economic Development in CT 2USDA Grant Funds Second Phase of Bio-Energy Research Community Economic Development in CT 3Unveiling Breakthroughs in Clinical & Cellular Immunology 2Unveiling Breakthroughs in Clinical & Cellular Immunology 3
... GE Healthcare and Intermountain Health Care ... software program that would accelerate the adoption of electronic ... was announced at the annual Healthcare Information and Management ... companies hope to take the clinical knowledge that IHC ...
... next big thing is not enough. , ,Whether you're ... occupying several hard-won niches, or a high-energy start-up, protecting ... Miller, an intellectual property lawyer with Michael Best & ... eInnovate, a Milwaukee-based technology forum, Miller said some researchers ...
... Small Tree Communications , a niche hardware company that ... funding round from Chippewa Valley Angel Investors Network . ... our business faster by getting our products to market sooner," ... us to get office space and equipment, and to develop ...
Cached Biology Technology:GE and Intermountain want to streamline nationwide patient data 2Protect your intellectual property before it's too late 2Protect your intellectual property before it's too late 3Chippewa Valley angels invest in network hardware company 2Chippewa Valley angels invest in network hardware company 3
... to slightly cloudy liquid. Yellow, oily, ... set, each containing 10 ml of ... following proportions by weight: 85% Drakeol ... emulsifier), and 0.1% Mycobacterium butyricum ...
... Easy and Cost effective - Utilizes hands-off ... , No grinding - Extract DNA ... grinding tools between samples , Robust ... beat and homogenize without tube breakage , ...
... secretion of cytoplasmic granules, is a ... of leukocytes (e.g. basophils, neutrophils, eosinophils, ... histamine, these secretory granules contain many ... and many proteases (Hallgren, 2001). Tryptase, ...
... the things youll be telling others after you ... Erica Golemis, One look at the table of ... in protein interaction will tell you immediately that ... part of your personal protein chemistry library. You ...
Biology Products: