Navigation Links
'Universal' vaccines could finally allow for wide-scale flu prevention
Date:2/27/2012

d their model using an archetype of the universal vaccine. In recent years, outbreaks of potent flu strains such as avian flu in 2003 and advances in biotechnology have spurred research teams at pharmaceutical companies and government organizations such as the National Institutes of Health to work on cross-protective vaccines, Arinaminpathy said. Projections for a publicly available vaccine range from one to five years.

Current flu vaccines are produced to counter the influenza strains that the World Health Organization predicts will dominate a particular flu season. Inoculation typically focuses on protecting people who are vulnerable to the virus. However, this approach does not provide long-term or widespread immunity, Arinaminpathy said. The flu virus is always evolving, and so vaccines need to be updated each year.

The reason is that these vaccines zero in on hemagglutinin (HA), proteins protruding from the virus' surface that allow it to attach to and invade host cells. Small mutations in these highly adaptive appendages can create new versions of the virus that often are invulnerable to the vaccine designed for their former selves, a tactic known as "immune escape."

Universal vaccines instead bypass the protruding HA surface to target more constant proteins with less evolutionary flair, Arinaminpathy said. Because HAs are still active, the virus may still infect people, but it cannot wreak the same havoc.

The various universal vaccines being developed target different viral components, but they all have the potential to slow viral transmission across many flu variants, Arinaminpathy said. The researchers used that overarching feature in their model vaccine. The researchers then simulated the effectiveness of their basic universal vaccine in two types of flu outbreak: pandemic and epidemic.

A flu pandemic the sudden and rapid spread of a new, highly contagious strain is difficult to predict and typically imposs
'/>"/>

Contact: Morgan Kelly
mgnkelly@princeton.edu
609-258-5729
Princeton University
Source:Eurekalert  

Page: 1 2 3 4 5

Related biology news :

1. Promising results in mice on needle-free candidate universal vaccine against various flu viruses
2. SentiSight 3.0 Universal Object Recognition Technology Available Now From Neurotechnology
3. Universal donor immune cells
4. Discovery of natural antibody brings a universal flu vaccine a step closer
5. Johns Hopkins scientists expose cancer cells universal dark matter
6. Adjuvant combo shows potential for universal influenza vaccine
7. New report underlines the threat to universal access to HIV prevention, treatment and care due to a slow-down in treatment scale-up and waning political will
8. Human rights protections essential in drive for universal access
9. At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to finish what weve started
10. New steps toward a universal flu vaccine
11. ASU scientists develop universal DNA reader to advance faster, cheaper sequencing efforts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Universal' vaccines could finally allow for wide-scale flu prevention
(Date:7/11/2014)... Using spider toxins to study the proteins that let ... say they have stumbled upon a biological tactic that ... insect plagues in a safe and environmentally responsible way. ... be lethal for one species and harmless for a ... target specific pests without harming beneficial species like bees. ...
(Date:7/10/2014)... June 27, 2014  The American Academy of ... of Standards and Technology (NIST) and the Department ... research and forensic science expert members to the ... an element of the NIST,s Organization of Scientific ... the first appointments made to the new FSSB ...
(Date:7/10/2014)... 1, 2014 Smart technology emphasis grows ... and improved security: NXT-ID, Inc. (OTCBB: NXTD), eBay Inc. (NASDAQ: ... ), Apple Inc. (NASDAQ: AAPL ), Visa Inc. ... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused ... the second series of 30 second spots on CNBC for ...
Breaking Biology News(10 mins):Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5
... four genes newly associated with severe childhood obesity. They ... in severely obese children. The team found that ... to maintain protein receptors known to be involved in ... for the development of new drugs against obesity. ...
... UNTIL 1 P.M. EDT, APRIL 7, 2013, Cleveland: A compound ... popular energy drinks has been found to promote atherosclerosis ... to Cleveland Clinic research published online this week in the ... that bacteria living in the human digestive tract metabolize the ...
... Kidney stones usually make their presence known suddenly, often ... Each year in the U.S. more than a million ... nephrolithiasis. The total annual cost of treatment exceeds $2.1 ... Information Clearinghouse. Although kidney stone pain may ...
Cached Biology News:Finding genes for childhood obesity 2Cleveland Clinic researchers discover new link between heart disease and red meat 2Cleveland Clinic researchers discover new link between heart disease and red meat 3Flies reveal kidney stones in-the-making 2Flies reveal kidney stones in-the-making 3
(Date:7/11/2014)... 2014 /CNW/ - Sunovion Pharmaceuticals Canada Inc. (Sunovion) today ... acetate) for use as a once-daily adjunctive therapy for ... who are not satisfactorily controlled with conventional therapy.  APTIOM ... under 18 years of age. Epilepsy ... according to Epilepsy Canada, it affects 0.6% of the ...
(Date:7/10/2014)... Ouagadougou, Burkina Faso (PRWEB) July 10, 2014 ... Burkina Faso, today have access to an additional ... to increase access to contraception at all levels ... combining a lower-dose formulation of a widely used ... injection system. , Burkina Faso is the first ...
(Date:7/10/2014)... 10, 2014 Understanding the need for ... lines, and the gap that currently exists in this ... its industry-leading portfolio of validated ion channel and GPCR ... cell lines, as ion channels control many critical physiological ... activity creates the potential to treat a variety of ...
(Date:7/10/2014)... 2014 Robert Harman, DVM, Founder and CEO ... proud to announce the relaunch of his highly informative blog, ... series called “ What are Stem Cells ?” Dr. ... straightforward foundation in the basics of stem cell therapy so ... right type of treatment when considering regenerative medicine. , A ...
Breaking Biology Technology:Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3
... 27 Warner Chilcott Limited (Nasdaq: WCRX ... Inc. has submitted a New Drug Application for WC ... and Drug Administration. About Warner Chilcott ... currently focused on the women,s healthcare and dermatology segments ...
... Record and A Year,s Supply of Breathalicious ... Sweet at the White HouseLOS ANGELES, March ... Bulletin Board: FVRL), which through its wholly-owned ... consumer-controlled Personal Health Records ("PHRs") ( www.mymedicalrecords.com ...
... to stockholders through liquidationA decisive victory for stockholder ... L.P. ("BVF"), today announced that stockholders of Avigen ... remove the existing Board of Directors of Avigen ... took place earlier today at the special meeting ...
Cached Biology Technology:Warner Chilcott Announces NDA Submission for Low Dose Oral Contraceptive 2Warner Chilcott Announces NDA Submission for Low Dose Oral Contraceptive 3MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 2MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 3MMR and Dancing Paws to Participate in Joint Sales Effort to Provide Personal Health Records for Pets 4Biotechnology Value Fund, L.P. Announces Overwhelming Support to Remove the Board of Directors of Avigen, Inc. at Special Meeting of Stockholders 2
... II xi cell, 16 cm, is used for ... proteins in agarose gels. The cell is supplied ... central cooling core with gaskets, lower buffer chamber, ... 4 sandwich clamps, upper buffer dam, casting stand ...
CleanCut agarose is used to prepare genomic DNA plugs for use in pulsed field gel electrophoresis (PFGE) applications. Supplied as a 12 ml solution of 2% agarose....
...
... uses the Adept CE 4100 high pressure dual ... dual wavelength detector for added flexibility. ... software and interface unit, CE 4901., The CE ... also be used with Windows 98 and 2000, ...
Biology Products: