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Unique database of cancer -- designed to personalize treatment -- is launched
Date:10/26/2010

clinically important questions. We want to define a clinical situation and always connect it back to the patient," he says. "That is the essence of personalized medicine."

Weiner says physicians today are still using 19th and 20th century tools "even though we have 21st century information. Physicians evaluate their patients in much the same way they have for the last 100 years they take a history, a physical exam, and then use additional exams to make a treatment plan.

"This hasn't changed because there is no effective way to connect clinical and nonclinical information in an efficient way, and we need analytical capabilities that permit us to make sense of the vast amount of information that is now being collected," he says.

"The purpose of G-DOC is to demonstrate that collecting and analyzing molecular and clinical data in tandem will permit use to make more informed decisions about patient management," Weiner says.

The hope is that every cancer patient treated by Lombardi oncologists will agree to have information on their cancer and their treatment history placed in G-DOC, with strict privacy protections, says Subha Madhavan, PhD, director of clinical research informatics the person who has led the development of G-DOC. The type of data collected and analyzed will depend on studies that require a powerful integrative and analytic platform like G-DOC, she says. And while some will be privately held within Georgetown prior to publication and broader release, other data will be accessible by the public.

"The goal of systems medicine is to empower the next generation physician to make the best decision for patients based on evidence, and G-DOC is a critical test of that approach," says Madhavan.

Madhavan says systems medicine represents an evolution in health care, integrating science, medicine, informatics, engineering, environment, economics, public policy and more to better understand and care for the human co
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Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

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