Navigation Links
Undertreatment of cardiovascular disease in rheumatoid arthritis patients following a heart attack
Date:5/27/2011

Results of a study, involving 98,454 patients demonstrated that at 30 days following their first heart attack, RA patients were approximately 20% less likely to be prescribed standard MI treatments, such as statins and betablockers, compared to healthy patients. These finding remained relatively unchanged at 180 days, further highlighting differences between the two groups, with a high number being prescribed the current standards of care within the 180 day period (statins 80%, betablockers 82%, clopidogrel 70%, aspirin 79%) in general.

"Previous research has established that RA patients have an increased risk of cardiovascular disease (CVD). The results of our study suggest that CVD may be under treated in these patients, due to concerns regarding the use of multiple medications or patient compliance," said Dr. Jesper Lindhardsen of the Gentofte University Hospital in Copenhagen, Denmark. "Clinicians may find post-MI treatment in RA patients more complicated which would explain the lower propensity towards prescribing treatment; however this may be increasing the CVD burden seen in RA patients. Additional research is required in this area to establish whether further education is needed."

In the study, researchers identified 98,454 patients (39.4% female), who had suffered an MI for the first time, using the Danish National nationwide individual level registers, which included pharmacy records. Researchers examined 1,113 RA patient's prescriptions (62.5% female) between their first MI and 30 and 180 days following, allowing them to determine whether standard MI treatments had been prescribed or not. Odds ratios were calculated to determine the influence of RA, and were obtained using the statistical tool multivariate logistic regression modelling which included gender, age, co-morbidity and income.

Results of a separate study show that duration of RA doesn't further impact on CV risk over time

Results of one further study investigating the risk of CVD in RA patients, demonstrated that duration of RA did not increase the CVD risk over time. Previous studies have suggested that a number of factors may contribute to RA patients developing CVD such as chronic systemic inflammation or adverse effects associated with RA treatments. However the findings in this study showed no difference in the risk of CVD between patients who had suffered with RA for less or more than 10 years.


'/>"/>

Contact: Rory Berrie
rory.berrie@cohnwolfe.com
44-790-151-3297
European League Against Rheumatism
Source:Eurekalert

Related biology news :

1. Changing views about saturated fat and cardiovascular disease
2. Why do preterm deliveries pose cardiovascular risks for moms?
3. Penn Medicine researcher receives $6 million grant for cardiovascular disease study
4. Columbia University Medical Center announces 2010 Katz Prizes in cardiovascular research
5. Cardiovascular Innovation Institute researchers receive over $2 million grant from NIH
6. Significant weight-loss from surgery decreases risk for cardiovascular disease in women
7. EPA holds seminar on air pollution and cardiovascular disease
8. UH engineers to improve test for cardiovascular disease
9. CNIC and Banco Santander set up research project on early cardiovascular risk factors
10. New cancer therapy may fight cardiovascular disease
11. WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2017)... ALBANY, New York , April 19, 2017 /PRNewswire/ ... highly competitive, as its vendor landscape is marked by ... in the market is however held by five major ... and Safran. Together these companies accounted for nearly 61% ... majority of the leading companies in the global military ...
(Date:4/11/2017)... Fla. , April 11, 2017 ... and secure authentication solutions, today announced that it ... Intelligence Advanced Research Projects Activity (IARPA) to develop ... Thor program. "Innovation has been a ... IARPA,s Thor program will allow us to innovate ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... ... April 25, 2017 , ... LABS, Inc. (LABS) announced in December 2016 that ... test menu: Nucleic Acid Testing (NAT) for ZIKV; and Enzyme Immunoassays (EIAs) specific for ... NAT screening for blood donors under an Investigational New Drug (IND) study protocol. ...
(Date:4/26/2017)... 2017  Genisphere LLC, provider of the 3DNA ... collaborative and sponsored research agreement with the University ... The overall goal of the partnership is to ... designs and formulations after in vivo ... vasculature as well as inflammatory responses, demonstrating various ...
(Date:4/25/2017)... 2017 Providence -based ... novel immune-modulating technology to an undisclosed global pharmaceutical company, ... Tregitopes, pronounced TĀ·rejĀ·itopes, are a set of ... CEO Annie De Groot and EpiVax ... an autoimmune disease therapy, Tregitopes are capable of ...
(Date:4/24/2017)... Yorba Linda, Ca (PRWEB) , ... April 24, ... ... can protect proteins from thermal denaturation in a cellular milieu; however, the broad ... by a lack of simple platforms with sensitive quantitative readouts. Cell-based thermal stabilization ...
Breaking Biology Technology: