Navigation Links
Undertreatment of cardiovascular disease in rheumatoid arthritis patients following a heart attack
Date:5/27/2011

Results of a study, involving 98,454 patients demonstrated that at 30 days following their first heart attack, RA patients were approximately 20% less likely to be prescribed standard MI treatments, such as statins and betablockers, compared to healthy patients. These finding remained relatively unchanged at 180 days, further highlighting differences between the two groups, with a high number being prescribed the current standards of care within the 180 day period (statins 80%, betablockers 82%, clopidogrel 70%, aspirin 79%) in general.

"Previous research has established that RA patients have an increased risk of cardiovascular disease (CVD). The results of our study suggest that CVD may be under treated in these patients, due to concerns regarding the use of multiple medications or patient compliance," said Dr. Jesper Lindhardsen of the Gentofte University Hospital in Copenhagen, Denmark. "Clinicians may find post-MI treatment in RA patients more complicated which would explain the lower propensity towards prescribing treatment; however this may be increasing the CVD burden seen in RA patients. Additional research is required in this area to establish whether further education is needed."

In the study, researchers identified 98,454 patients (39.4% female), who had suffered an MI for the first time, using the Danish National nationwide individual level registers, which included pharmacy records. Researchers examined 1,113 RA patient's prescriptions (62.5% female) between their first MI and 30 and 180 days following, allowing them to determine whether standard MI treatments had been prescribed or not. Odds ratios were calculated to determine the influence of RA, and were obtained using the statistical tool multivariate logistic regression modelling which included gender, age, co-morbidity and income.

Results of a separate study show that duration of RA doesn't further impact on CV risk over time

Results of one further study investigating the risk of CVD in RA patients, demonstrated that duration of RA did not increase the CVD risk over time. Previous studies have suggested that a number of factors may contribute to RA patients developing CVD such as chronic systemic inflammation or adverse effects associated with RA treatments. However the findings in this study showed no difference in the risk of CVD between patients who had suffered with RA for less or more than 10 years.


'/>"/>

Contact: Rory Berrie
rory.berrie@cohnwolfe.com
44-790-151-3297
European League Against Rheumatism
Source:Eurekalert

Related biology news :

1. Changing views about saturated fat and cardiovascular disease
2. Why do preterm deliveries pose cardiovascular risks for moms?
3. Penn Medicine researcher receives $6 million grant for cardiovascular disease study
4. Columbia University Medical Center announces 2010 Katz Prizes in cardiovascular research
5. Cardiovascular Innovation Institute researchers receive over $2 million grant from NIH
6. Significant weight-loss from surgery decreases risk for cardiovascular disease in women
7. EPA holds seminar on air pollution and cardiovascular disease
8. UH engineers to improve test for cardiovascular disease
9. CNIC and Banco Santander set up research project on early cardiovascular risk factors
10. New cancer therapy may fight cardiovascular disease
11. WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/18/2016)... , March 18, 2016 ... Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical infrastructure ... & security companies in the border security market and the ... and Europe has led visiongain ... companies improved success. --> defence & security ...
(Date:3/15/2016)... York , March 15, 2016 ... market report published by Transparency Market Research "Digital Door Lock ... and Forecast 2015 - 2023," the global digital door lock ... 731.9 Mn in 2014 and is forecast to grow at ... Growth of micro, small and medium enterprises (MSMEs) across the ...
(Date:3/14/2016)... MELBOURNE, Florida , March 14, 2016 ... on the growing mobile commerce market, announces the airing of ... York channels starting the week of March 21 st . ... and CNBC, including its popular Squawk on the Street show. ... company focused on the growing mobile commerce market, announces the ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... ... Scientists at the University of Athens say they have evidence that the variety ... that could lead to one good one. Surviving Mesothelioma has just posted an article ... team evaluated 98 mesothelioma patients who got a second kind of drug ...
(Date:5/25/2016)... ... May 25, 2016 , ... ... and Drug Administration (FDA) has granted the company’s orphan drug designation request covering ... orphan drug designation granted by the FDA. , Spinocerebellar ataxia is a ...
(Date:5/24/2016)... ... May 24, 2016 , ... Last week, Callan Capital, ... executives and entrepreneurs, held The Future of San Diego Life Science event at the ... life science community attended the event with speakers Dr. Rich Heyman, former CEO of ...
(Date:5/23/2016)... ... 23, 2016 , ... PrecisionAg® Media has released its latest ... The paper outlines the key trends that are creating both opportunities and challenges ... lot of highs and lows as the precision agriculture market has grown and ...
Breaking Biology Technology: