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Understanding why some people have propensity to disease
Date:5/14/2012

iology and disease.

"We have much to learn about the nuclear-receptor-DNA interaction and the factors that influence it," Sladek said. "While nuclear receptors have been investigated heavily for their role in physiology and disease and are themselves targets of many successful drugs, we still do not have a complete understanding of their role in disease susceptibility nor in individual responses to drug treatments. This grant will allow us to better define what kind of sequences the nuclear receptors bind to, and help with other ways of examining what kind of genes the nuclear receptors regulate."

Sladek will be joined in the research by the following colleagues at UCR: Tao Jiang, a professor of computer science and engineering and the grant's co-principal investigator; Thomas Girke, an associate professor of bioinformatics; and two postdoctoral researchers.


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Contact: Iqbal Pittalwala
951-827-6050
University of California - Riverside
Source:Eurekalert  

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