Navigation Links
Understanding robustness in organisms -- a potential weapon against infectious diseases
Date:6/16/2010

College Park, MD (June 17, 2010) -- "Robust" is an adjective appreciatively applied to certain vintage wines, but when describing viruses and pathogens, robustness is a property that may be much less desirable. It evokes drug resistant microbes and other superbugs that can wreak havoc as researchers struggle to deal with new pandemics. How can we undercut this robustness?

A study in the journal Chaos, which is published by the American Institute of Physics (AIP), examines the ability of organisms to survive and sustain themselves in the face of various kinds of change. C. Brandon Ogbunugafor and his team at Yale University looked at new and existing data to determine the strengths and weaknesses of the study of robustness as a formal concept and its application in infectious systems. They found that while one must be careful in defining and applying the premise of robustness, the infectious disease paradigm was full of examples where further application might be useful. While preliminary, Dr. Ogbunugafor's work could have far-reaching implications in a world with increasing numbers of drug-resistant strains of disease.

"We believe that further application of the robustness concept, with experiments designed to test it in other systems, might aid in how we study and treat infectious diseases of various kinds," Ogbunugafor says. "This is quite exciting, as it uncovers fertile ground for the application of an exciting concept in the context of infectious diseases that is highly relevant to everyday life."

While there are still a number of unanswered questions, researchers are hopeful that the application of this concept could help predict how organisms evolve. Ultimately, Ogbunugafor predicts that the application of the robustness concept could serve as a "Rosetta Stone" for predictive evolution, which might constitute the next paradigm shift in evolutionary biology. "Perhaps by understanding how robustness manifests in diseases like influenza and malaria, for example, we'll be better able to predict drug resistant variants before they arise and stay a step ahead of the enemy in the ubiquitous arms race between us and the microbes that threaten our well-being," he says.


'/>"/>

Contact: Jason Socrates Bardi
jbardi@aip.org
301-209-3091
American Institute of Physics
Source:Eurekalert

Related biology news :

1. Stretching molecules yields new understanding of electricity
2. NIST scientists gain new core understanding of nanoparticles
3. Pollution dispersion research aids understanding of 2002 break-up of Antarctic ozone hole
4. Space technology revolutionizes archaeology, understanding of Maya
5. Scripps Research team provides groundbreaking new understanding of stem cells
6. Body builders -- the worms that point the way to understanding tissue regeneration
7. Understanding night blindness and calcium
8. Understanding Climates Influence on Human Evolution -- March 31 public event
9. New understanding of proteins role in brain
10. LSUHSC research increases understanding of drug metabolism
11. Model may offer better understanding of embryonic development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/4/2017)... , Jan. 4, 2017  CES 2017 – ... sensor technology, today announced the launch of two ... systems, the highly-accurate biometric sensor modules that incorporate ... technology, experience and expertise. The two new designs ... specifically for hearables, and Benchmark BW2.0, a 2-LED ...
(Date:12/22/2016)... MOUNTAIN VIEW, Calif. , Dec. 20, 2016  As ... all levels, 23andMe, the leading personal genetics company, recently released ... Only Me . The book focuses on the topics ... the Next Generation Science Standards (NGSS) taught in elementary school ... the second in a series by illustrator Ariana Killoran ...
(Date:12/20/2016)... , Dec. 20, 2016 The ... sharing, rental and leasing is stoking significant interest ... radio frequency technology, Bluetooth low energy (BLE), biometrics ... as the next wave of wireless technologies in ... access system to advanced access systems opens the ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... Minnesota (PRWEB) , ... January 19, 2017 , ... ... research organization with services spanning the full spectrum of drug and device development, ... research services to pharma/device companies and clinicians, today announced Verified Clinical Trials ...
(Date:1/19/2017)... , Jan. 18, 2017  Northwest Biotherapeutics, Inc. (OTCQB: ... personalized immune therapies for operable and inoperable solid tumor ... Chief Technical Officer of NW Bio, will present at ... 2017, at the Hyatt Regency Hotel in ... chair the session entitled "New Therapeutic Approaches – Expanding ...
(Date:1/19/2017)... -- BD (Becton, Dickinson and Company) (NYSE: BDX ), ... a live webcast of its Annual Meeting of Shareholders on Tuesday, ... webcast can be accessed from the BD corporate website at ... 2017. ... BD BD is a global medical technology company that is ...
(Date:1/18/2017)... to a new market research report "In situ Hybridization Market by Technique (FISH, ... Laboratories, Academic and Research Institutions) - Global Forecast to 2021" published by MarketsandMarkets, ... 557.1 Million in 2016, growing at a CAGR of 5.8%. ... ... Logo ...
Breaking Biology Technology: