Navigation Links
Understanding robustness in organisms -- a potential weapon against infectious diseases
Date:6/16/2010

College Park, MD (June 17, 2010) -- "Robust" is an adjective appreciatively applied to certain vintage wines, but when describing viruses and pathogens, robustness is a property that may be much less desirable. It evokes drug resistant microbes and other superbugs that can wreak havoc as researchers struggle to deal with new pandemics. How can we undercut this robustness?

A study in the journal Chaos, which is published by the American Institute of Physics (AIP), examines the ability of organisms to survive and sustain themselves in the face of various kinds of change. C. Brandon Ogbunugafor and his team at Yale University looked at new and existing data to determine the strengths and weaknesses of the study of robustness as a formal concept and its application in infectious systems. They found that while one must be careful in defining and applying the premise of robustness, the infectious disease paradigm was full of examples where further application might be useful. While preliminary, Dr. Ogbunugafor's work could have far-reaching implications in a world with increasing numbers of drug-resistant strains of disease.

"We believe that further application of the robustness concept, with experiments designed to test it in other systems, might aid in how we study and treat infectious diseases of various kinds," Ogbunugafor says. "This is quite exciting, as it uncovers fertile ground for the application of an exciting concept in the context of infectious diseases that is highly relevant to everyday life."

While there are still a number of unanswered questions, researchers are hopeful that the application of this concept could help predict how organisms evolve. Ultimately, Ogbunugafor predicts that the application of the robustness concept could serve as a "Rosetta Stone" for predictive evolution, which might constitute the next paradigm shift in evolutionary biology. "Perhaps by understanding how robustness manifests in diseases like influenza and malaria, for example, we'll be better able to predict drug resistant variants before they arise and stay a step ahead of the enemy in the ubiquitous arms race between us and the microbes that threaten our well-being," he says.


'/>"/>

Contact: Jason Socrates Bardi
jbardi@aip.org
301-209-3091
American Institute of Physics
Source:Eurekalert

Related biology news :

1. Stretching molecules yields new understanding of electricity
2. NIST scientists gain new core understanding of nanoparticles
3. Pollution dispersion research aids understanding of 2002 break-up of Antarctic ozone hole
4. Space technology revolutionizes archaeology, understanding of Maya
5. Scripps Research team provides groundbreaking new understanding of stem cells
6. Body builders -- the worms that point the way to understanding tissue regeneration
7. Understanding night blindness and calcium
8. Understanding Climates Influence on Human Evolution -- March 31 public event
9. New understanding of proteins role in brain
10. LSUHSC research increases understanding of drug metabolism
11. Model may offer better understanding of embryonic development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... WASHINGTON , April 24, 2017 ... counsel and partner with  Identity Strategy Partners, LLP ... "With or without President Trump,s March 6, ... Foreign Terrorist Entry , refugee vetting can be instilled ... refugee resettlement. (Right now, all refugee applications are ...
(Date:4/13/2017)... 2017 According to a new market research report ... Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region ... expected to grow from USD 14.30 Billion in 2017 to USD 31.75 ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... 2017 , ... NetDimensions has been ranked as a Leader ... Corporate Learning, 2017. , Aragon Research defines Leaders as organizations who possess comprehensive ... those strategies. NetDimensionsā€™ ranking as a Leader due to its strengths in: , ...
(Date:5/23/2017)... Diego, CA (PRWEB) , ... May 23, 2017 , ... ... matrix of polymeric molecules, can cause diverse pathologies ranging from food poisoning and catheter ... impact of biofilms is in the tens of billions of dollars per year, there ...
(Date:5/22/2017)... ... 22, 2017 , ... Cancer diagnostics and pathology workflow solution ... the Association for Pathology Informatics Annual Summit at the Wyndham Grand ... Cancer Diagnostic Cockpit and Consultation Portal, Inspirata will present research it led to ...
(Date:5/18/2017)... ... May 18, 2017 , ... Dr. Ralph Mobbs ... the Prince Of Wales Private Hospital. The procedure was performed on a 46-year-old ... failed conservative treatments prior to undergoing surgery. , The AxioMed viscoelastic disc is ...
Breaking Biology Technology: