Navigation Links
Understanding binge eating and obesity
Date:3/19/2014

March 19, 2014 Researchers at the University of Cambridge have developed a novel method for evaluating the treatment of obesity-related food behavior. In an effort to further scientific understanding of the underlying problem, they have published the first peer-reviewed video of their technique in JoVE, the Journal of Visualized Experiments.

In the video, the authors demonstrate their means of objectively studying the drivers and mechanisms of overconsumption in humans. To do this, they assesses their subject's willingness to work or pay for food, and they simultaneously track the corresponding brain activity using an MRI scanner.

"We present alternative ways of exploring attitudes to food by using indirect, objective measuressuch as measuring the amount of energy exerted to obtain or view different foods, as well as determining brain responses during the anticipation and consumption of desirable foods," said the lab's principal investigator, Dr. Paul Fletcher. He and his colleagues use participant hand-grip intensity (referred to as "grip force" in the video) to calculate the motivation for a given food reward.

According to Dr. Fletcher, typical approaches for evaluating anti-obesity type drugs rely on more subjective methodslike having test subjects self-report their ratings of hunger and cravings.

"When a person is asked how much they subjectively desire a food, they may feel pressured to give a 'correct' rather than a true answer," said Dr. Fletcher, "[Our] grip force task may, under certain circumstances, present a more accurate reflection of what they really want."

Dr. Fletcher and his colleagues brought the technique to JoVE after using it in their earlier publication, "Food images engage subliminal motivation to seek food," published in 2011. They decided to publish a video capturing the protocol "Because it offered the opportunity to demonstrate the methods more fully," he said.

In the video, Dr. Fletcher expands on the purpose of publishing the method with JoVE. "Individuals new to the technique may struggle because there aren't many examples of grip-force tasks published in the literature, and there are no full and clear descriptions of how to design and set up the tasks," he said.

With rising concerns surrounding obesity, researchers can use the technique presented in the JoVE video to determine the efficacy of a potential emerging market in anti-obesity medicine.


'/>"/>

Contact: Phil Meagher
phil.meagher@jove.com
617-245-0137
The Journal of Visualized Experiments
Source:Eurekalert  

Related biology news :

1. Plant biology discovery furthers scientists understanding of plant growth and development
2. Big stride in understanding PP1, the ubiquitous enzyme
3. Research of zebrafish neurons may lead to understanding of birth defects like spina bifida
4. Finding common ground fosters understanding of climate change
5. Cell division finding could boost understanding of cancer
6. IMPRESSIONS: Advancing understanding of the consequences of high-end climate change
7. Understanding secondary light emission by plasmonic nanostructures may improve medical imaging
8. New DRI project aimed at understanding Mercury dynamics in the Arctic tundra
9. Reinterpreting origins, examining skeletal preservation, and understanding volcanics
10. Study breaks blood-brain barriers to understanding Alzheimers
11. Study of rodent family tree puts brakes on commonly held understanding of evolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Understanding binge eating and obesity
(Date:12/12/2016)... , Dec. 12, 2016  Researchers at ... possibilities for graphene by combining the material with ... highly sensitive pressure detector able to sense pulse, ... a small spider.  The research ... can be read here:  http://science.sciencemag.org/content/354/6317/1257 ...
(Date:12/8/2016)... ALAMEDA, Calif. , Dec. 8, 2016  Singulex, ... Single Molecule Counting technology, entered into a license and ... in serving science. The agreement provides Singulex access to ... Europe is used to diagnose ... the United States to aid in assessing ...
(Date:12/7/2016)... December 7, 2016 BioCatch , the global ... its patent portfolio, which grew to over 40 granted and pending patents. ... , , ... patent entitled " System, Device, and Method Estimating Force Applied ... device makers to forego costly hardware components needed to estimate the force ...
Breaking Biology News(10 mins):
(Date:1/20/2017)... ... , ... The two newest companies to join the University City Science Center’s ... from The Wistar Institute, and Sanguis, launched by a trio of students from the ... Vironika is developing a treatment for a chronic viral infection and its associated diseases, ...
(Date:1/20/2017)... (PRWEB) , ... January 20, ... ... in Less Exposure Surgery (LES®) Technologies, announced today the next evolution in ... Pedicle Screw System platform). In contrast to the competition, SpineFrontier is focused ...
(Date:1/19/2017)... , Jan. 19, 2017 /PRNewswire -- WuXi ... device open-access capability and technology platform, today announced ... leading biology focused preclinical drug discovery contract research ... will become a wholly-owned subsidiary of WuXi, and ... competences and providing greater services. The acquisition will ...
(Date:1/19/2017)... GAITHERSBURG, Md. , Jan. 19, ... Altimmune, Inc., a privately-held immunotherapeutics company targeting infectious ... agreement for the merger of PharmAthene and Altimmune ... Novartis Venture Fund, HealthCap, Truffle Capital and Redmont ... and diversified immunotherapeutics company with four clinical stage ...
Breaking Biology Technology: