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Under the right conditions, peptide blocks HIV infection at multiple points along the way
Date:7/24/2012

"Our work provides new insights into the ability of defensins to recognize and neutralize diverse pathogens, including HIV," Melikyan says. This research reveals that human neutrophil peptide 1 can bind various viral and cellular targets and that a previously unappreciated feature is essential for its anti-HIV activity, possibly its propensity to form large complexes, Melikyan explains.

The team's findings suggest a new avenue of research for combatting HIV and viruses that infiltrate cells in a similar manner.


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Contact: Angela Hopp
240-283-6614
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

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