Navigation Links
Uncultured bacteria found in amniotic fluids of women who experience preterm births
Date:1/5/2009

CLEVELANDResearchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

Using gene-cloning techniques, researchers discovered that approximately 60 percent of the bacteria present in women with intra-amniotic inflammations were missed by traditional culture testing considered the gold standard for finding bacterial infections.

The findings were reported in the January issue of the Journal of Clinical Microbiology.

For the first time, the researchers identified a comprehensive list of microbial species in intra-amniotic infections by using new DNA methods to track down the presence of bacteria. To increase their accuracy the investigators used a combination of analyses including proteomics results of amniotic fluid and histological analysis of the placenta to corroborate the infection and inflammation.

Intra-amniotic inflammation is known to set off spontaneous births of preterm babies at less than 32 weeks, said Yiping Han, associate professor of dental medicine at Case Western Reserve University and lead investigator on the study of 46 women of which 44 experienced preterm births. Han has previously done a number of research projects examining the link between oral bacteria and preterm birth.

In the present study, bacteria levels from the amniotic fluids of pregnant women with signs or symptoms of preterm births were compared to those from a control group of 16 women without such manifestations and who delivered at term. The amniotic fluid of the control group came from amniocenteses for genetic screenings or analyses to check fetal lung maturity and showed no signs of bacteria even by DNA methods.

"Because culturing is not finding all bacteria present in the amniotic fluid, this calls for new detection methods," Han
'/>"/>

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

3

GOOD

Page: 1 2

Related biology news :

1. Shuttle brings space-grown strep bacteria back for study
2. The worlds oldest bacteria
3. Bacteria from sponges make new pharmaceuticals
4. Boston University biomedical engineers find chink in bacterias armor
5. University of Leicester scientists discover technique to help friendly bacteria
6. Spaceflight shown to alter ability of bacteria to cause disease
7. A tiny pinch from a z-ring helps bacteria cells divide
8. Legionnaires bacterial proteins work together to survive
9. Scripps research team blocks bacterial communication system to prevent deadly staph infections
10. NSF awards Stevens team $1 million for research on smart, bacteria-repellent nanohydrogels
11. Chemical compound present in detergents produce bacteria alterations in agricultural soils

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...he linchpin of the environment, where atmosphere, ...y students see soil as "just dirt" a place to gro... are challenged with the task of helping students ...f soil in the environment. , A collaborative pr...t University of Nebraska-Lincoln, Oregon State Uni...
(Date:11/25/2009)...ssors recently received funding from the National ...ficial to understanding the environment. The three... assistant professor in the Department of Biologic...arate research projects. , His first project, ti... Functions from the Leaf to the Landscape," will e...
(Date:11/24/2009)...ibed by traditional healers in Brazil to treat a r...o fever and flu. , Now for the first time, resear...ientifically prove the pain relieving properties o...int. , Testing this ancient South American herb o...was able to show that when prepared as a ,tea, th...
Breaking Biology News(10 mins):It's not just dirt! 2Kent State University professors focus research on the environment with grants totaling $890,000 2Got a pain? -- Have a cup of Brazilian mint 2Abaxis Inc to Present at the Sidoti 26amp 3B Company Second Annual New York Institutional Investor Forum 6169 1Cardio Vascular Medical Device Launches Corporate Website 6164 1Cardio Vascular Medical Device Launches Corporate Website 6164 2Executives Reveal Secrets to Capitalize on New Developments in Pharmaceutical Marketing Research 6159 1Executives Reveal Secrets to Capitalize on New Developments in Pharmaceutical Marketing Research 6159 2
...entists at The Scripps Research Institute are repo...molecule known as an LPA receptor have fertility p...a major role in conception. , In the latest issue...mice that lack LPA receptors, which normally appea...fertility problems. These mice are able to produce...
...s one of the most common viruses in America, and o...t inside almost any kind of human cell, reproduce ... causing everything from recurrent genital blister... kill, and it may increase susceptibility to many ...ists haven,t fully understood how the herpes simpl...
... cellular signaling protein Wnt, which is involved...to disease progression of both rheumatoid arthriti...l., "Expression profiles and functional analyses o...ears in the July issue of The American Journal of ...t is best known as a proto-oncogene because its di...
Other Biology News:Scripps research scientists identify infertility molecule 2Scripps research scientists identify infertility molecule 3Scripps research scientists identify infertility molecule 4Scripps research scientists identify infertility molecule 5Achilles heel of the herpes virus possibly found 2Achilles heel of the herpes virus possibly found 3Achilles heel of the herpes virus possibly found 4Arthritis: What Wnt wrong? 2
(Date:11/25/2009)...Nov. 25 /PRNewswire/ - Cytochroma today announced ...f Directors. Dr. Moldt will replace Mr. Ulrik Spor...Board. The number of Board members remains unchang...elcome Peter Moldt to the board and look forward t...ytochroma continues to make progress in becoming a...
(Date:11/25/2009)...K, Nov. 25 Reportlinker.com announ... in its catalogue: ,, Brazil Bioethanol Market....reportlinker.com/p0165503/Brazil-Bioethanol-Marke...l Bioethanol Market Analysis and Forecasts to 2013...d analysis and forecasts of the global bioethanol ...
(Date:11/24/2009)...ble in German . , Whether it,s CD packaging...adio Frequency Identification) are increasingly fi...ossible to label objects or goods and identify the...e scanner can read and process the data contained ... under production conditions of up to 100 degrees ...
(Date:11/24/2009)... Ambassador to also Visit Detroit , ...David Appia, French Ambassador for International I...rance Agency, , , , ,What: Ambassador Appia is av...usiness initiatives adopted by France to further d...e for innovation and development., , ,When: Availa...
Breaking Biology Technology:Cytochroma Announces Appointment of Peter Moldt to Board of Directors 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 3Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 4Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 5Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 6Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 7Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 8Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 9Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 10Intelligence inside metal components 2
...ions has announced that it will increase its C-Rea...C-Reactive Protein. , , C-Reactive Protein is a ...er for inflammation, meaning its presence indicate...Inflammation is a normal response to a number of p...on. Inflammation is also believed to play a role i...
...rations Increase 25 Percent to $62.6 Million - , ...e - , , INCLINE VILLAGE, Nev., May 7 PDL BioPhar...nancial results for the first quarter ended March ...rations for the first quarter of 2009 were $62.6 m...or the same period in 2008. The increase was prima...
...ic Inc. (OTC Bulletin Board: TBIO) announces the f...nomic Inc. First Quarter 2009 Earnings Release, ...Wednesday, May 13, 2009 @ 5:00 p.m. Eastern, ...?id=6 , How: Live over the Internet --...e address above., Contact: Investor Relati...
Other Biology Technology:PDL BioPharma Announces First Quarter 2009 Financial Results 2PDL BioPharma Announces First Quarter 2009 Financial Results 3PDL BioPharma Announces First Quarter 2009 Financial Results 4PDL BioPharma Announces First Quarter 2009 Financial Results 5PDL BioPharma Announces First Quarter 2009 Financial Results 6PDL BioPharma Announces First Quarter 2009 Financial Results 7PDL BioPharma Announces First Quarter 2009 Financial Results 8PDL BioPharma Announces First Quarter 2009 Financial Results 9Webcast Alert: Transgenomic Inc. Announces First Quarter 2009 Earnings Release Conference Call Webcast 2
... was tested on rat tissue extracts (liver, kidney,...) extract. It was also tested with microsomal frac...plication: A simple and reliable method for measur...d on the detection of the inorganic phosphate rele...
...ve stress is the condition in which a lack of bala...ious antioxidants. Oxidative stress appears to be... including artherosclerosis, chronic inflammatory ...s several antioxidant systems that are very import...
FlowJo from Tree Star Inc
...ytic degradation is critical to the maintenance of...proteins as important and diverse as those involve...sponse, antigen presentation, modulation of cell s...lation, transcription, and signalling factors. The...
Biology Products: