Navigation Links
Uncultured bacteria found in amniotic fluids of women who experience preterm births
Date:1/5/2009

CLEVELANDResearchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

Using gene-cloning techniques, researchers discovered that approximately 60 percent of the bacteria present in women with intra-amniotic inflammations were missed by traditional culture testing considered the gold standard for finding bacterial infections.

The findings were reported in the January issue of the Journal of Clinical Microbiology.

For the first time, the researchers identified a comprehensive list of microbial species in intra-amniotic infections by using new DNA methods to track down the presence of bacteria. To increase their accuracy the investigators used a combination of analyses including proteomics results of amniotic fluid and histological analysis of the placenta to corroborate the infection and inflammation.

Intra-amniotic inflammation is known to set off spontaneous births of preterm babies at less than 32 weeks, said Yiping Han, associate professor of dental medicine at Case Western Reserve University and lead investigator on the study of 46 women of which 44 experienced preterm births. Han has previously done a number of research projects examining the link between oral bacteria and preterm birth.

In the present study, bacteria levels from the amniotic fluids of pregnant women with signs or symptoms of preterm births were compared to those from a control group of 16 women without such manifestations and who delivered at term. The amniotic fluid of the control group came from amniocenteses for genetic screenings or analyses to check fetal lung maturity and showed no signs of bacteria even by DNA methods.

"Because culturing is not finding all bacteria present in the amniotic fluid, this calls for new detection methods," Han
'/>"/>

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Shuttle brings space-grown strep bacteria back for study
2. The worlds oldest bacteria
3. Bacteria from sponges make new pharmaceuticals
4. Boston University biomedical engineers find chink in bacterias armor
5. University of Leicester scientists discover technique to help friendly bacteria
6. Spaceflight shown to alter ability of bacteria to cause disease
7. A tiny pinch from a z-ring helps bacteria cells divide
8. Legionnaires bacterial proteins work together to survive
9. Scripps research team blocks bacterial communication system to prevent deadly staph infections
10. NSF awards Stevens team $1 million for research on smart, bacteria-repellent nanohydrogels
11. Chemical compound present in detergents produce bacteria alterations in agricultural soils
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... 44th Rosenstiel Award for Distinguished Work in Biomedical Science ... mechanisms of genomic instability and its implications for the ... alumnus to win the Rosenstiel Award; the first, Rod ... is the Charles A. Janeway Professor of Pediatrics and ... investigator at the Howard Hughes Medical Institute at Boston ...
(Date:10/14/2014)... in Cancer Research shows SIRT6—a protein known ... promote the development of skin cancers by turning on ... sun-damaged skin cells. , Previously considered protective, SIRT6 is ... that help regulate genomic stability and prevent some of ... DNA damage, which can lead to cancer. This study, ...
(Date:10/14/2014)... is how to produce enough food to feed the ... Agriculture Organization of the United Nations predicts that food ... to feed a growing global population, and plants are ... production. Plants—grains, cereals, fruits, vegetables, and more—feed humans ... must tap into our knowledge of how plants work ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
... new study suggest that past climate changes and sea level ... the Amazon region of South America. Today, the ... on earth, yet the reasons why this came to be ... researchers studied three species of leafcutter ants from Central and ...
... some of the most pressing international issuessuch as renewable ... more pressing than ever that an informed public be ... science. The Ecological Society of America (ESA),s 93rd Annual ... the importance of using a broad range of tools ...
... The University of Texas at Austin is part of ... should simplify the water desalination process, increasing access to ... we make the desalination process more efficient with better ... gallon of water, which will expand the availability of ...
Cached Biology News:Study suggests past climate changes may have promoted the formation of new species in the Amazon 2Training future scientists at the Ecological Society of America's 93rd Annual Meeting 2New chlorine-tolerant, desalination membrane hopes to boost access to clean water 2
(Date:10/19/2014)... (PRWEB) October 20, 2014 ... Industry Meeting (ABIM). ABIM will take ... More information about ABIM 2014 is now ... , Delegates representing companies and organizations from ... and obtain information on the latest products ...
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report defines ... analysis and forecast of revenue. This market is estimated ... million by 2019, at a Compound Annual Growth Rate ... through the TOC of the Asia-Pacific Speech Analytics market ... provided. It also provides a glimpse of the segmentation ...
(Date:10/19/2014)... According to market research report “Outdoor ... Wireless gateways)]- Global Advancements, Forecasts and Analysis (2013 ... Wi-Fi market with analysis and forecasting of the ... the drivers and the restrains for this market ... challenges. , Browse 65 market data tables and ...
(Date:10/18/2014)... October 18, 2014 The Asian arthroscopic ... Asia with analysis and forecast of revenue. The arthroscopic ... $712.3 million by 2018, at a CAGR of 6.5% ... of the Asian arthroscopic devices market, to get an ... a glimpse of the segmentation of arthroscopic devices market ...
Breaking Biology Technology:The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 4The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4
... energy research , , MONTREAL, July 7 /PRNewswire/ ... company, today announced that it will jointly form an ... and the Alberta Energy Research Institute (AERI). , The ... of novel catalytic conversion processes to produce advanced biofuels ...
... Reportlinker.com just added a new market research report ... World Endoscopy Systems Market , ... , , This report analyzes ... Million. The major product segments analyzed are Endoscopes, ...
... US Venture Capital firm Burrill & Company has invested in ... a Taiwan based company with operations in Taipei and South ... company with a proprietary drug delivery technology based on a ... developing and commercializing a portfolio of "super-generics" with advantageous delivery ...
Cached Biology Technology:Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 2Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 3New Report Just Published: World Endoscopy Systems Market Report 2New Report Just Published: World Endoscopy Systems Market Report 3New Report Just Published: World Endoscopy Systems Market Report 4New Report Just Published: World Endoscopy Systems Market Report 5New Report Just Published: World Endoscopy Systems Market Report 6New Report Just Published: World Endoscopy Systems Market Report 7New Report Just Published: World Endoscopy Systems Market Report 8New Report Just Published: World Endoscopy Systems Market Report 9New Report Just Published: World Endoscopy Systems Market Report 10New Report Just Published: World Endoscopy Systems Market Report 11New Report Just Published: World Endoscopy Systems Market Report 12New Report Just Published: World Endoscopy Systems Market Report 13New Report Just Published: World Endoscopy Systems Market Report 14New Report Just Published: World Endoscopy Systems Market Report 15New Report Just Published: World Endoscopy Systems Market Report 16New Report Just Published: World Endoscopy Systems Market Report 17New Report Just Published: World Endoscopy Systems Market Report 18New Report Just Published: World Endoscopy Systems Market Report 19New Report Just Published: World Endoscopy Systems Market Report 20New Report Just Published: World Endoscopy Systems Market Report 21Burrill & Company Invests in Taiwan Liposome Company 2Burrill & Company Invests in Taiwan Liposome Company 3
... Tecan provides labware carriers to suit ... encountered in the life science laboratory. Labware ... on the worktable. Mounting is simple for ... system that ensures carriers are correctly guided ...
... Protea is pleased to introduce its new ... of lyophilized standard proteins for use in ... laboratories. Proteas Protein Standards are high ... calibration of protein analyses by electrospray ionization ...
Determine relative degree of protein binding to phosphoinositides...
Anti-Protein Kinase-A (PKA) Regulatory subunit IIB; rabbit host...
Biology Products: