Navigation Links
Uncultured bacteria found in amniotic fluids of women who experience preterm births
Date:1/5/2009

CLEVELANDResearchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

Using gene-cloning techniques, researchers discovered that approximately 60 percent of the bacteria present in women with intra-amniotic inflammations were missed by traditional culture testing considered the gold standard for finding bacterial infections.

The findings were reported in the January issue of the Journal of Clinical Microbiology.

For the first time, the researchers identified a comprehensive list of microbial species in intra-amniotic infections by using new DNA methods to track down the presence of bacteria. To increase their accuracy the investigators used a combination of analyses including proteomics results of amniotic fluid and histological analysis of the placenta to corroborate the infection and inflammation.

Intra-amniotic inflammation is known to set off spontaneous births of preterm babies at less than 32 weeks, said Yiping Han, associate professor of dental medicine at Case Western Reserve University and lead investigator on the study of 46 women of which 44 experienced preterm births. Han has previously done a number of research projects examining the link between oral bacteria and preterm birth.

In the present study, bacteria levels from the amniotic fluids of pregnant women with signs or symptoms of preterm births were compared to those from a control group of 16 women without such manifestations and who delivered at term. The amniotic fluid of the control group came from amniocenteses for genetic screenings or analyses to check fetal lung maturity and showed no signs of bacteria even by DNA methods.

"Because culturing is not finding all bacteria present in the amniotic fluid, this calls for new detection methods," Han
'/>"/>

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

3

GOOD

Page: 1 2

Related biology news :

1. Shuttle brings space-grown strep bacteria back for study
2. The worlds oldest bacteria
3. Bacteria from sponges make new pharmaceuticals
4. Boston University biomedical engineers find chink in bacterias armor
5. University of Leicester scientists discover technique to help friendly bacteria
6. Spaceflight shown to alter ability of bacteria to cause disease
7. A tiny pinch from a z-ring helps bacteria cells divide
8. Legionnaires bacterial proteins work together to survive
9. Scripps research team blocks bacterial communication system to prevent deadly staph infections
10. NSF awards Stevens team $1 million for research on smart, bacteria-repellent nanohydrogels
11. Chemical compound present in detergents produce bacteria alterations in agricultural soils
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/21/2010)... ecosystems caught between the land and the stream, ... managing and protecting riparian areas as well as ... are investigating new approaches in experiential learning, or ... approaches is photography. By taking photographs of a ... photography), you can see if changes have occurred. ...
(Date:3/21/2010)... <A HREF=",http://chinese.eurekalert.org/zh/emb_releases/2010-03/asu-etb031810.php,">Chinese . TEMPE, Ariz. ... Congress to ban the export of electronics waste ... even worse, say authors of an article from ... appearing online today. , The authors call into ... "backyard recycling" of electronics waste primarily old ...
(Date:3/21/2010)... Seaweed could hold the key to tackling obesity after it ... per cent, new research has shown. , Now the team ... see if they can develop foods that help you lose ... led by Dr Iain Brownlee and Prof Jeff Pearson have ... commercially-used seaweed could reduce the amount of fat absorbed by ...
Breaking Biology News(10 mins):Learning about riparian areas from photographs 2E-waste trade ban won't end environmental threat 2Seaweed to tackle rising tide of obesity 2Introducing All New IEHP Superhero to Battle Childhood Obesity 54248 1Introducing All New IEHP Superhero to Battle Childhood Obesity 54248 2Introducing All New IEHP Superhero to Battle Childhood Obesity 54248 3ParagonRx Sponsors Webinar on Demand By DSEC on Role of Drug Safety Officers 13507 1Formal education lessens the impact of Alzheimers disease 9539 1Formal education lessens the impact of Alzheimers disease 9539 2
... South America's Amazon basin are "breathing" far harder ?cycling the ... Most of the carbon being exhaled ?or outgassed ?as carbon ... 5 years sequestered in the trees, other plants and soils ... the July 28 issue of Nature. , It had been ...
... modulate the consequences of eating a high-fat, Western diet, new ... , Mice with an excess of liver X receptor (LXRa), ... the high cholesterol and blood vessel plaques exhibited by animals ... a normal, balanced diet, the excess receptors worsened blood lipid ...
... look at specific climate statistics from the north Pacific ... in Banff National Park. The University of Alberta doctoral ... between the North Pacific Oscillation (NPO) and a mammal ... are able to determine positive, average and negative NPO ...
Other Biology News:Amazon source of 5-year-old river breath 2Excess liver gene protects against high-fat diet 2Ocean climate predicts elk population in Canadian Rockies 2
(Date:3/17/2010)... ANN ARBOR, Mich.---In findings that took the experimenters three ... collaborators have demonstrated that light itself can twist ribbons ... current edition of Science . , Matter readily ... lenses and polarizing 3-D movie glasses. But the opposite ...
(Date:3/17/2010)... March 17  OriGene Technologies, Inc., a leading ... $16 million Series B financing led by ... OriGene,s previous investors Morningside Venture Investments and ... round.  The proceeds from the funding will be used ...
(Date:3/17/2010)... BALTIMORE , March 17 Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), ... enhance the value of oncology drugs, today announced its financial results for the third  fiscal ... in the Company,s Form 10-Q at www.championsbiotechnology.com . , ... ...
(Date:3/17/2010)... BOISE, Idaho , March 17 A new professional services company has been launched focused on accelerating the connections of university-based bioscience research ... strategic officer. , ... , , ... ...
Breaking Biology Technology:Light twists rigid structures in unexpected nanotech finding 2Light twists rigid structures in unexpected nanotech finding 3OriGene Technologies Raises $16 Million to Build the Largest Collection of Next Generation Monoclonal Antibodies (TrueMAB(TM)) to Cover the Majority of Human Proteome 2OriGene Technologies Raises $16 Million to Build the Largest Collection of Next Generation Monoclonal Antibodies (TrueMAB(TM)) to Cover the Majority of Human Proteome 3Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 2Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 3Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 4Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 5Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 6Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 7Champions Biotechnology Reports Fiscal 2010 Third Quarter Financial Results 8Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 2Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 3Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 4
... Tom Barrett and Milwaukee officials on Wednesday announced plans ... citywide wireless network accessible to all residents. , ,The ... fully wireless large city in America, built at no ... Barrett's office. , ,"This initiative constitutes a multi-million dollar ...
... Drug Administration (FDA) approval or authorization is critical to ... and reimbursement issues can be just as determinative. ... an insurer for the product. "Reimbursement" is how much ... ,Unlike the FDA, insurers include economic analyses in their ...
... Sonic Foundry, Inc. has earned certified status ... to recognize and share expertise among companies in the ... Sonic Foundry achieved a Microsoft Competency in the area ... have earned certified status. The Microsoft Partner Program allows ...
Other Biology Technology:Milwaukee announces citywide wireless initiative 2On track with the FDA -- But what about your coverage and reimbursement strategy? 2On track with the FDA -- But what about your coverage and reimbursement strategy? 3On track with the FDA -- But what about your coverage and reimbursement strategy? 4
...
... FL is equipped with ... measurement technologies that complement ... advanced features of Fluoroskan ... Fluoroskan Ascent FL provides ...
...
...
Biology Products: