Navigation Links
Uncovering the genetics of prostate cancer
Date:1/20/2011

Prostate cancer is known to occur typically in older men. Yet some patients are younger than 50 years at the time of diagnosis. Scientists assume that these cases might be the key to understanding the biology of this disease. Early prostate cancer might be a subtype which is characterized by a relatively small number of genetic modifications. Cancer researchers believe it is likely that these include a number of what are called 'driver mutations' which extremely promote the development and growth of prostate cancer. Moreover, researchers assume that prostate cancer with hereditary background, which is not yet entirely understood, is more likely to occur in men under age 50.

In a research network funded by the German Ministry of Research and Education with 7.5 million, physicians and scientists are now planning to uncover the genetics of early prostate cancer. This is the aim of a collaborative effort involving scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), the National Center for Tumor Diseases (NCT) in Heidelberg and colleagues from the University Medical Center Hamburg-Eppendorf (UKE) and Martini-Klinik in Hamburg-Eppendorf. The European Molecular Biology Laboratory (EMBL) in Heidelberg and the Max Planck Institute of Molecular Genetics in Berlin will also participate in the project.

The project is part of the International Cancer Genome Consortium (ICGC). This consortium globally captures characteristic genetic modifications of the most important types of cancer. By now, more than 20 countries have joined the endeavor.

After the project was officially approved in December, work will start in January to decipher the tumor cell genome of 250 prostate cancer patients aged 50 or younger and to compare it with the gene sequences from healthy cells of the same men. This will help to discover those gene mutations that cause and promote prostate cancer. With this giant project, the researc
'/>"/>

Contact: Dr. Sibylle Kohlstaedt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Uncovering secrets of life in the ocean
2. Uncovering the secrets of ulcer-causing bacteria
3. Uncovering lithiums mode of action
4. Uncovering the mystery of a major threat to wheat
5. American College of Medical Genetics receives $13.5M NIH contract
6. The American Society of Human Genetics hosts 58th Annual Meeting in Philadelphia
7. Modern genetics vs. ancient frog-killing fungus
8. New research helps explain genetics of Parkinsons disease
9. New genetic markers for ulcerative colitis identified, researchers report in Nature Genetics
10. Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29
11. Study examining role of genetics and environment in type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... As our ability to assess the pandemic risk from ... developments, we must not allow ourselves to become complacent ... an international consortium of scientists. , Influenza pandemics arise ... have yet to develop widespread immunity – spreads in ... in the past 100 years, the worst of which ...
(Date:10/15/2014)... rapidly and to an unexpected extent. The outbreak does ... the virus shows a new disease dynamic in regions, ... reason, the German National Academy of Sciences Leopoldina, acatech ... the Union of the German Academies of Sciences and ... today. , In the statement the academies call for ...
(Date:10/15/2014)... awarded the 44th Rosenstiel Award for Distinguished Work in ... exploring the mechanisms of genomic instability and its implications ... the second alumnus to win the Rosenstiel Award; the ... , Alt is the Charles A. Janeway Professor of ... and an investigator at the Howard Hughes Medical Institute ...
Breaking Biology News(10 mins):Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2
... winds caused by global warming, seeds and pollen are being ... a couple of degrees may increase the dispersal of plants ... forest clearings after felling or forest fires. University ... the impact of global warming on seed and pollen dispersal. ...
... dog owner has not come home to a broken vase ... the house? By ingeniously setting up conditions where the owner ... an offense, Alexandra Horowitz, Assistant Professor from Barnard College in ... dogs in the recently published "Canine Behaviour and Cognition" Special ...
... discovered a potential new way to treat childhood epilepsy ... Gabriella D,Arcangelo and her colleagues have published their research ... (in press) and the paper has just appeared ... the researchers are investigating the molecular basis of the ...
Cached Biology News:Global warming increasing the dispersal of flora in Northern forests 2What really prompts the dog's 'guilty look' 2Rutgers research tackles childhood epilepsy 2
(Date:10/20/2014)... PLAINSBORO, N.J. (PRWEB) October 20, 2014 ... that the Sidney Kimmel Cancer Center at Thomas ... program. , Through the Strategic Alliance Partnership ... and OncLive will collaborate to raise awareness of ... cancer treatment, and other projects. Clinicians and other ...
(Date:10/19/2014)... October 20, 2014 OCTOBER ... Meeting (ABIM). ABIM will take place ... information about ABIM 2014 is now available ... Delegates representing companies and organizations from all ... obtain information on the latest products and ...
(Date:10/19/2014)... Asia-Pacific Speech Analytics market report defines and segments the ... of revenue. This market is estimated to grow from ... at a Compound Annual Growth Rate (CAGR) of 23.9% ... of the Asia-Pacific Speech Analytics market report to get ... provides a glimpse of the segmentation in the market, ...
(Date:10/19/2014)... According to market research report “Outdoor Wi-Fi Market ... Global Advancements, Forecasts and Analysis (2013 - 2018)", ... with analysis and forecasting of the global revenues. ... and the restrains for this market with the ... Browse 65 market data tables and 69 figures ...
Breaking Biology Technology:Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 4
... 26 Amedica Corporation, an,orthopedic implants company focused ... U.S. Food and Drug Administration,has granted 510(k) marketing ... Valeo Pedicle Screw system is a low profile ... aimed at allowing surgeons,greater flexibility in the positioning ...
... WALTHAM, Mass., Nov. 26 Millennium Research ... data from both orthopedic surgeons and rheumatologists, shows ... Q3 2007 compared to Q3,2006. While treatments are ... the products they use in these procedures., ...
... Opportunity Presented, CHARLES TOWN, W.Va., Nov. ... RBRM), a provider of treatment for,diabetic peripheral ... successfully concluded analysis of the recent volatility ... the Board of Directors., (Logo: ...
Cached Biology Technology:Amedica Receives FDA 510(k) Clearance for Valeo(TM) Pedicle Screw System 2Hyaluronic Acid Knee Procedures Grow 38% from Q3 2006 to Q3 2007 2ReBuilder Medical Technologies, Inc.'s Recent Stock Price Volatility Explained 2
... controls for monitoring Aldolase tests. 2 ... with targeted manufacturing values at 4 ... 3 IU/L. 30-day shelf life ... C. Level 1: 3 x 3 ...
Request Info...
One-step, microplate or cuvet, colorimetric, linear detection range 0.2 mg/dL to 20 mg/dL. Procedure: 20 min....
Recombinant Mouse Noggin...
Biology Products: