Navigation Links
Uncovering the genetics of prostate cancer
Date:1/20/2011

Prostate cancer is known to occur typically in older men. Yet some patients are younger than 50 years at the time of diagnosis. Scientists assume that these cases might be the key to understanding the biology of this disease. Early prostate cancer might be a subtype which is characterized by a relatively small number of genetic modifications. Cancer researchers believe it is likely that these include a number of what are called 'driver mutations' which extremely promote the development and growth of prostate cancer. Moreover, researchers assume that prostate cancer with hereditary background, which is not yet entirely understood, is more likely to occur in men under age 50.

In a research network funded by the German Ministry of Research and Education with 7.5 million, physicians and scientists are now planning to uncover the genetics of early prostate cancer. This is the aim of a collaborative effort involving scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), the National Center for Tumor Diseases (NCT) in Heidelberg and colleagues from the University Medical Center Hamburg-Eppendorf (UKE) and Martini-Klinik in Hamburg-Eppendorf. The European Molecular Biology Laboratory (EMBL) in Heidelberg and the Max Planck Institute of Molecular Genetics in Berlin will also participate in the project.

The project is part of the International Cancer Genome Consortium (ICGC). This consortium globally captures characteristic genetic modifications of the most important types of cancer. By now, more than 20 countries have joined the endeavor.

After the project was officially approved in December, work will start in January to decipher the tumor cell genome of 250 prostate cancer patients aged 50 or younger and to compare it with the gene sequences from healthy cells of the same men. This will help to discover those gene mutations that cause and promote prostate cancer. With this giant project, the researc
'/>"/>

Contact: Dr. Sibylle Kohlstaedt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Uncovering secrets of life in the ocean
2. Uncovering the secrets of ulcer-causing bacteria
3. Uncovering lithiums mode of action
4. Uncovering the mystery of a major threat to wheat
5. American College of Medical Genetics receives $13.5M NIH contract
6. The American Society of Human Genetics hosts 58th Annual Meeting in Philadelphia
7. Modern genetics vs. ancient frog-killing fungus
8. New research helps explain genetics of Parkinsons disease
9. New genetic markers for ulcerative colitis identified, researchers report in Nature Genetics
10. Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29
11. Study examining role of genetics and environment in type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... mechanism in part of the brain that is key to ... type 1 and type 2 diabetes. The findings are published ... National Academies of Sciences . , "We,ve discovered that ... the hypothalamus known as the ventromedial nucleus sets a ... the blood," said lead author Sabrina Diano, professor in the ...
(Date:7/28/2014)... the top 10 U.S. cities that have seen an ... as frequent road closures, overwhelmed storm drains and compromised ... NOAA technical report. , This nuisance flooding, caused by ... coasts, between 300 and 925 percent since the 1960s. ... Frequency Changes around the United States, also finds Annapolis ...
(Date:7/28/2014)... areas of the Earth that are high priorities for ... is particularly vulnerable, as it has the lowest fraction ... any continent in ,refugia, areas of biological diversity ... relatively constant during times of great environmental change. The ... Scandinavia and Scotland. , The biggest refugia are ...
Breaking Biology News(10 mins):Glucose 'control switch' in the brain key to both types of diabetes 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Study finds Europe's habitat and wildlife is vulnerable to climate change 2
... was discovered in large numbers along the west coast of ... the past two winters has been 100%, but researchers at ... can now say that the species copes with cold winters ... proved to be tolerant of low temperatures. Large populations of ...
... Wisconsin-Madison limnologist Stephen Carpenter has been awarded the ... award for water-related activities, it was announced in ... award, which comes with $150,000 and a specially ... work contributes broadly to the conservation and protection ...
... A mother,s iron deficiency early in pregnancy may have ... the child, even if the lack of iron is not ... Rochester Medical Center study published in the scientific journal ... might not notice or treat mild or moderate iron deficiency, ...
Cached Biology News:UW-Madison lake scientist gets world's top water prize 2Pre-conception and early pregnancy iron deficiency harms brain 2Pre-conception and early pregnancy iron deficiency harms brain 3
(Date:7/28/2014)... According to a new market ... Medicine (Bone and Joint) Market (By Technology - ... Applications - Bone Graft Substitutes, Osteoarticular Diseases, Allogeneic ... Analysis, Size, Share, Growth, Trends and Forecast, 2013 ... joint) market was valued at USD 2.6 billion ...
(Date:7/28/2014)... July 28, 2014 /PRNewswire/ -   JOLT , a ... companies to join its growing portfolio of startups. Next-level ... Toronto,s JOLT accelerator, and Cohort four ... roster. Since its launch in July ... raised  $7.5M of financing. Now at 23 investments, JOLT,s ...
(Date:7/28/2014)... 28, 2014 Immunomic Therapeutics, Inc. (ITI) ... further develop potential treatments for glioblastoma multiforme (GBM), the ... with their patented vaccine platform, LAMP-vax. , The ... based on the work of John H. Sampson, MD, ... Preston Robert Tisch Brain Tumor Center at Duke University ...
(Date:7/28/2014)... Washington, DC (PRWEB) July 28, 2014 It’s ... their GI Bill benefits to further their post-secondary education are ... says a study released this year. And according to an ... of this shortfall is veteran students’ uninformed choice of college ... , The details of the study: Some 51.7 percent of ...
Breaking Biology Technology:Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4JOLT Announces the Next 6 Startups to Join its Summer 2014 Cohort 2JOLT Announces the Next 6 Startups to Join its Summer 2014 Cohort 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 2String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 4Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 2Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 3Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 4
... Carbon nanotubes have a sound future in ... worlds first all-nanotube transistor radios to prove it., ... all of the active functionality in the devices, ... of carbon-nanotube materials into high-speed analog electronics and ...
... significant step towards improving the design of future ... lab-on-a-chip devices, researchers with the U.S. Department of ... the University of California (UC) at Berkeley, have ... study of gas-phase reactions on the microscale. , ...
... Jan. 28 MedPredict has published,"Thought Leader Insight ... insight for pharma and biotech companies with a,stake ... this disease area., "Given the size of ... for long-term disease control, it is not surprising ...
Cached Biology Technology:New kind of transistor radios shows capability of nanotube technology 2Berkeley scientists bring MRI/NMR to microreactors 2Berkeley scientists bring MRI/NMR to microreactors 3Berkeley scientists bring MRI/NMR to microreactors 4Berkeley scientists bring MRI/NMR to microreactors 5New Report Tackles the Changing Landscape for Alzheimer's Diagnostics and Treatments 2
... active ingredient in Molecular Probes. SlowFadeAntifade ... to act as a free radical ... Our original SlowFade formulation (S-2828) was ... of fluorescein to almost zero (Figure ...
b6-2A12...
... in this kit are prepared with pure ... Biochains Mitochondria Isolation Kit is designed to ... fast and easy way. One kit is ... isolations (enriching mitochondria from 10 20 ...
... The Freedom EVOlyzer is Tecans new ... automated microplate processing. Freedom EVOlyzer is a ... includes state-of-the art reader, washer and incubation ... software. The Freedom EVOlyzer is available in ...
Biology Products: