Navigation Links
Uncharged organic molecule can bind negatively charged ions
Date:2/26/2008

BLOOMINGTON, Ind. -- Indiana University Bloomington chemists have designed an organic molecule that binds negatively charged ions, a feat they hope will lead to the development of a whole new molecular toolbox for biologists, chemists and medical researchers who want to remove chlorine, fluorine and other negatively charged ions from their solutions.

"What we've done is create an efficient synthesis that gives us access to a whole new family of binding agents," said Amar Flood, who reports the discovery with postdoctoral scholar Yongjun Li in Angewandte Chemie this week. "The synthesis is extremely modular, as well, so we imagine these molecules can be easily modified to bind a wide variety of negative ions with great specificity."

Chelating agents are small molecules that grab atoms (or, sometimes, even smaller molecules) out of a solution and hold onto them. Chelators play a valuable role in both nature and laboratory settings. For example, the human protein calmodulin not only grabs positively charged calcium ions out of the solution surrounding it, it also influences cell processes according to how many calcium ions it has grabbed. In labs, EDTA (ethylenediaminetetraacetic acid) is frequently used to remove calcium and magnesium ions so that chemical reactions go faster or more efficiently.

Many organic molecules exist that can bind positively charged ions, or cations, and this has much to do with the fact that it is easy to synthesize organic molecules with negatively charged parts. It is those negatively charged parts that interact with positive ions, or cations, grabbing them out of solution and holding onto them so the cations cannot react or interfere with other processes.

Attempts at manufacturing organic binding agents with positively charged parts is not hard, but designing them in such a way that they don't attract the attention of solvent molecules has been a major challenge for chemists.

Flood an
'/>"/>

Contact: David Bricker
brickerd@indiana.edu
812-856-9035
Indiana University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Is it organic or not?
2. Study reveals that nitrogen fertilizers deplete soil organic carbon
3. Surprise in the organic orchard -- a healthier worm in the apple
4. New microsensor measures volatile organic compounds in water and air on-site
5. Stanford researchers make first direct observation of 3-D molecule folding in real time
6. Rice scientists make breakthrough in single-molecule sensing
7. Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth
8. New book presents methods to poke and prod individual molecules
9. Curry-derived molecules might be too spicy for colorectal cancers
10. NIH recognizes Clemson nanotechnology for molecule tracking
11. New technique reveals subtle force-induced changes in biomolecules conformation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Uncharged organic molecule can bind negatively charged ions
(Date:9/1/2014)... Mass-- Conventional wisdom has long held that corals ... coral reefs are passive organisms that rely ... such as nutrients and oxygen. But now scientists ... (WIS) in Israel have found that they are ... water into turbulent patterns that greatly enhance their ...
(Date:9/1/2014)... About 50 years ago, electron microscopy revealed the presence ... around and disappear. But scientists still don,t know what ... of proteins are believed to be crucial to the ... new approach to disease treatment., In the Journal ... call to investigators from various backgrounds, from biophysics to ...
(Date:8/31/2014)... A new blood test provides a fast and ... new proof-of-concept study shows. The newly developed test ... to detect active tuberculosis in children. The test ... tests in combination with speed of a blood ... for the diagnosis of tuberculosis in children, particularly ...
Breaking Biology News(10 mins):Nature's tiny engineers 2Nature's tiny engineers 3Scientists call for investigation of mysterious cloud-like collections in cells 2New tuberculosis blood test in children is reliable and highly specific 2
... German . , EASY-HIT** is a new cell-based ... This system was developed under the leadership of Professor Ruth ... the system are cultured human cells that allow HIV to ... producing a red fluorescent protein. The EASY-HIT technology can be ...
... Colo. (December 1, 2010) A major new study ... fetus to those smells and flavors, but physically changes the ... the future. "This highlights the importance of eating ... and nursing," said Josephine Todrank, PhD, who conducted the two-year ...
... from the UC Davis Health System have found that ... are significantly reduced in patients in the Sacramento area ... that affects about one in three U.S. adults and ... The study is the first to examine vitamin-D ...
Cached Biology News:A powerful new technology to identify HIV inhibitors 2Study shows pregnant mother's diet impacts infant's sense of smell 2Study finds low vitamin-d levels in northern California residents with metabolic syndrome 2Study finds low vitamin-d levels in northern California residents with metabolic syndrome 3Study finds low vitamin-d levels in northern California residents with metabolic syndrome 4
(Date:8/29/2014)... are based on electrons, but one of the most ... i.e. circuits based on light (photons) instead of electrons. ... a stream of single photons and control their direction. ... attempts to achieve this control, but now scientists at ... steady stream of photons emitted one at a time ...
(Date:8/29/2014)... Pittsburgh, PA (PRWEB) August 29, 2014 ... Chairman, Hub MacDonald, and colleague Koichiro Matsuda, Horiba Scientific, ... JASIS on September 5, 2014. JASIS , Asia’s ... September 3-5, 2014, in Makuhari Messe, Japan. , ... New Tools for Bioanalysis from Single Molecules to Single ...
(Date:8/29/2014)... California (PRWEB) August 29, 2014 ... of Energy's 2014 Hydrogen Production R&D Award ... -- by splitting water using sunlight. , Shared ... (NREL) and the University of Nevada, Las Vegas ... work developing models of photoelectrochemical solar-hydrogen production and ...
(Date:8/29/2014)... August 29, 2014 Intrinsic Imaging, ... certified, GAMP® 5 compliant imaging core lab, announced ... Phase II clinical trial to assess a new ... this trial, Intrinsic Imaging will provide comprehensive imaging ... protocol and charter development, site qualification, site training ...
Breaking Biology Technology:Breakthrough in light sources for new quantum technology 2Fifth Annual U.S. Symposium at JASIS Organized by Pittcon’s Program Chairman Hub MacDonald 2Livermore Team Awarded for Hydrogen Production Research 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2
... Consistent,Electronic Health Record for All Citizens Using City ... GREAT RIVER, N.Y., Oct. 16 Netsmart Technologies, ... for health and,human services organizations, today announced it ... contract by the City and County of San,Francisco, ...
... access to advanced gene-sequencing,technologies and gives new hope ... 16 Swedish Neuroscience,Institute (SNI) today announced that ... Hill Campus, the Center for Advanced Brain Tumor,Treatment ... patients diagnosed,with both benign and malignant brain tumors. ...
... Phase 3 CAPACITY Program - ... rate in CAPACITY -, BRISBANE, Calif., Oct. 16 ... 16, 2008, the Japanese,Ministry of Health, Labor and Welfare (MHLW) ... Ltd. to market pirfenidone,for the treatment of patients with idiopathic ...
Cached Biology Technology:Netsmart Technologies Selected by City and County of San Francisco to Provide Integrated Behavioral Healthcare Software System 2Netsmart Technologies Selected by City and County of San Francisco to Provide Integrated Behavioral Healthcare Software System 3Swedish in Seattle Unveils State-of-the-Art Brain Tumor Center Combining Advanced Treatment With Innovation in Research 2Swedish in Seattle Unveils State-of-the-Art Brain Tumor Center Combining Advanced Treatment With Innovation in Research 3Swedish in Seattle Unveils State-of-the-Art Brain Tumor Center Combining Advanced Treatment With Innovation in Research 4InterMune Reports Japanese Regulatory Approval of Pirfenidone in IPF 2InterMune Reports Japanese Regulatory Approval of Pirfenidone in IPF 3InterMune Reports Japanese Regulatory Approval of Pirfenidone in IPF 4
... cells for DNA isolation. Designed ... (includes 96 well plate adapters from ... the entire plate length (max capacity ... be used for soil, microorganisms, animal ...
Phospho- (Ser) 14-3-3 Binding Motif (4E2) Mouse mAb...
Rat polyclonal to acetyl Salicylic Acid ( Abpromise for all tested applications)....
Drugs and NO-drug Rat Anti-conjugated Acetyl Salicylic Acid Polyclonal Antibody...
Biology Products: