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Umeå University becomes national resource for advanced electron microscopy
Date:3/28/2014

and scientific coordinator for KBC."

"It shows again that the research environment at Ume Unversity which is based on collaboration over faculty and university boundaries is very successful and by sharing of internationally competitive equipment, we will hopefully also in the future attract top researchers at Ume."

The funding will be used to enhance two different techniques. The first technique is called cryo-electron microscopy, which makes it possible to study the smallest building blocks of life proteins and lipid membranes such as they occur in their natural water-soluble environment. The resolution is at atomic level. With the second technique, electron tomography, it is possible to visualise and analyse a sample in three dimensions. A sample with, for example, bacterial cytoskeleton can be rotated in the electron microscope and visualised from different angles.

"We study how microorganisms cause infectious diseases and how all living organisms function biochemically at molecular level," says Bernt Eric Uhlin, professor of medical microbiology and director of MIMS (Laboratory for Molecular Infection Medicine Sweden), which is the Swedish node in the international cooperation of molecular medical research with support from the Swedish Research Council.

"By visualising protein complexes and membrane structures, we learn how they are structured and what mechanisms and functions they fulfil in the cell."

Two new electron microscopes and tomography equipment will be purchased to the national platform thanks to new funding. The techniques will be very important to a large number of research projects conducted at Swedish universities. It will also further strengthen the international research centres in Ume: UCMR, MIMS and Ume Plant Science Centre (UPSC) with the Berzelius Centre for Forest Biotechnology.


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Contact: Bernt Eric Uhlin
bernt.eric.uhlin@molbiol.umu.se
46-907-856-731
Umea University
Source:Eurekalert  

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