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Ultrathin flexible brain implant offers unique look at seizures in NIH-funded research
Date:11/13/2011

hers said.

The researchers tested the flexible array on cats. Although mice and rats are used for most neuroscience research, cats have larger brains that are anatomically more like the human brain, with simplified folds and grooves.

The team evaluated the array in multiple contexts and brain areas. They found that it could record brain responses as the cats viewed simple objects, and sleep rhythms while the cats were under anesthesia. In one set of experiments, the researchers recorded brain activity during seizures that were induced with a drug.

"We were able to watch as spiral waves began and became self-sustaining," said Dr. Litt.

Using their flexible array technology, the researchers hope to identify these spiral brainwaves in people with epilepsy, to monitor seizures, and perhaps to control them. "We should be able to model the spirals and determine what kind of waveform can stop them. Or we can watch the spirals terminate spontaneously and try to reproduce what we see by stimulating the brain electrically," Dr. Litt said.


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Contact: Daniel Stimson
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke
Source:Eurekalert  

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