Navigation Links
Ultrasound shown to exert remote control of brain circuits
Date:10/29/2008

U research group discovered that remotely delivered low intensity, low frequency ultrasound (LILFU) increased the activity of voltage-gated sodium and calcium channels in a manner sufficient to trigger action potentials and the release of neurotransmitter from synapses. Since these processes are fundamental to the transfer of information among neurons, the authors pose that this type of ultrasound provides a powerful new tool for modulating the activity of neural circuits.

"Many of the stimulation methods used by neuroscientists require the use and implantation of stimulating electrodes, requiring direct contact with nervous tissue or the introduction of exogenous proteins, such as those used for the light-activation of neurons," Tyler explains.

The search for new types of noninvasive neurostimulation methods led them to revisit ultrasound.

"We were quite surprised to find that ultrasound at power levels lower than those typically used in routine diagnostic medical imaging procedures could produce an increase in the activity of neurons while higher power levels produced very little effect on their activity," Tyler says.

Other neuroscientists and engineers have also been rapidly developing new neurostimulation methods for controlling nervous system activity and several approaches show promise for the treatment of a wide variety of nervous system disorders. For example, Deep Brain Stimulation (DBS) and Vagal Nerve Stimulation (VNS) have been shown to be effective in the management of psychiatric disorders such as depression, bipolar disorders, post-traumatic stress disorder, and drug addition, as well as for therapies of neurological diseases such as Parkinson's disease, Alzheimer's disease, Tourette Syndrome, epilepsy, dystonia, stuttering, tinnitus, recovery of cognitive and motor function following stroke, and chronic pain. Up until now, these two techniques have captured the attention of physicians and scientists; however, the
'/>"/>

Contact: Margaret Coulombe
margaret.coulombe@asu.edu
480-727-8934
Arizona State University
Source:Eurekalert

13

GOOD

Page: 1 2 3

Related biology news :

1. Anti-tumor therapy with endoscopic ultrasound may fight cancer more safely and effectively
2. New 3-D ultrasound could improve stroke diagnosis, care
3. Chocolate bar shown to lower cholesterol
4. DNA methylation shown to promote development of colon tumors
5. Spaceflight shown to alter ability of bacteria to cause disease
6. Remote technology sees through ice, snow and hot air to monitor power plants
7. Scientists use remote satellite imaging to predict outbreaks of infectious disease
8. Digital cameras, remote satellites measure crop water demand
9. Harlequin frog rediscovered in remote region of Colombia
10. Climates remote control on hurricanes
11. MIT: Remote-control nanoparticles deliver drugs directly into tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... in the body, stem cells in the blood ... into mature immune cells that can fight off ... these cell populations, potentially leading to the development ... a team of researchers led by biologists at ... that, in mouse models, the molecule microRNA-146a (miR-146a) ...
(Date:5/21/2013)... most deadly when they metastasize and spread tumors throughout ... becomes very difficult for doctors to locate and treat ... the University of Missouri have found a way to ... they may be in the body. Michael Lewis, an ... Veterinary Medicine, says being able to target secondary tumors ...
(Date:5/21/2013)... at Chicago College of Medicine will study gender differences in ... energy source -- and how changes in fat metabolism play ... 4-year grant from the National Heart, Lung and Blood Institute. ... for energy. These changes may play a major role in ... and women, says E. Douglas Lewandowski, director of the UIC ...
Breaking Biology News(10 mins):Keeping stem cells strong 2MU researchers develop radioactive nanoparticles that target cancer cells 2Do men's and women's hearts burn fuel differently? 2
... and A*STAR,s Experimental Therapeutics Centre (ETC) today announced ... ETC,s new Singapore Screening Centre. This partnership will ... to biomedical researchers, enabling highly efficient drug screening ... conducts high-throughput screening to identify potential drug candidates ...
... This release is available in German . , ... membrane for the absorption of viruses like hepatitis C, herpes, ... germs. However, certain viruses, such as the human immunodeficiency virus ... membrane. Just how this infiltration occurs on a molecular level ...
... A "four-eyed" fish that sees simultaneously above and below ... how gene expression allows organisms to adapt to their environment. ... student, found a sharp divide between the upper and lower ... 12-inch fish closely related to guppies. The findings were published ...
Cached Biology News:Agilent Technologies and A*STAR launch all-in-one drug screening platform 2Scavenger cells accomplices to viruses 2UBC graduate student discovers key to 'bifocals' in mangrove fish species 2
(Date:5/21/2013)... study led by George Washington University Professor Tianshu ... ice in small droplets is strongly size-dependent, an ... nanoscale. The formation of ice at the nanoscale ... answer also has important implications for climate research ... ice from supercooled water is generally initiated by ...
(Date:5/21/2013)... , May 21, 2013 The ... and Transplant Association) is the biggest congress in ... therapy. Nearly 10,000 participants are in Istanbul ... latest research findings. New pioneering studies have been presented: ... FERRIC PYROPHOSPHATE (SFP) ADMINISTERED VIA HEMODIALYSATE REDUCES ESA USE" ...
(Date:5/21/2013)... Raleigh, NC (PRWEB) May 21, 2013 ... and financial services company for clinical trials, announced ... Aggregate Spend Solutions, LLC. Clinverse’s ClinPay® FLS ... automated investigator payment process. SpendMD ™, ... only complete solution for tracking and reporting transfer ...
(Date:5/21/2013)... According to a new market ... "Biochip Products and Services Market (Microarrays, Reagents, Drug Discovery, ... Share, Growth, Trends and Forecast, 2012 - 2018," the market was valued ... to grow at a CAGR of 10.1% from 2012 ... 4.7 billion in 2018. Browse the full ...
Breaking Biology Technology:Study led by GW professor provides better understanding of water's freezing behavior at nanoscale 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 3Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 2The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 4The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 5
... and CEO of Epic Systems , made a rare ... Promega BTC Center. The audience heard the CEO's perspective on ... company. , ,For over twenty years, Judy Faulkner had never ... participate on outside company boards or committees. The crowd was ...
... security conference and stayed at a hotel, which promoted wireless ... had implemented it so only those on the first floor ... purchase wireless Internet service when Im at seminars because I ... office. Out of curiosity, on my second night at the ...
... that it is producing the Wisconsin Intellectual Capital in ... from 8:30 a.m. to 3:45 p.m. at the Country ... medical device and technology cluster is a key element ... of Commerce (Commerce) Secretary Cory L. Nettles. This presentation ...
Cached Biology Technology:Epic's Founder Judy Faulkner Speaks on Culture, Business Beliefs, and Recruiting: WTN Exclusive Coverage 2Epic's Founder Judy Faulkner Speaks on Culture, Business Beliefs, and Recruiting: WTN Exclusive Coverage 3Wireless Are you at Risk and Liable? 2Wireless Are you at Risk and Liable? 3Wireless Are you at Risk and Liable? 4Medical Technologies and Devices Symposium 2
Human GATA-2 Affinity Purified Polyclonal Ab...
...
... priced, full ring small animal imaging PET ... microPET R4 low retail price, it outperfoms ... count rate performance, energy resolution, timing resolution, ... small animal PET (Positron Emission Tomography) imaging ...
... versatile liquid handling platforms and flexible robotic ... of life science applications.The Freedom EVO platform ... 100, 150 and 200 cm), giving all ... will advance with their application needs. ...
Biology Products: