Navigation Links
Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
Date:5/3/2012

Researchers at the National Institute of Standards and Technology (NIST) have developed a prototype bioreactora device for culturing cells to create engineered tissuesthat both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis. Tissue created this way might someday be used to replace, for example, damaged or diseased cartilage in the knee and hip.

Conventional methods for evaluating the development and properties of engineered tissue are time-consuming, destructive and need to be repeated many times. By using ultrasound to monitor tissue during processing without destroying it, the novel bioreactor could be a faster and less expensive alternative.

"Most bioreactors don't do any type of nondestructive evaluation," says NIST postdoctoral researcher Jenni Popp, first author of a new paper* about the instrument. "Having some sort of ongoing evaluation of the developing tissue is definitely novel."

Cartilage is smooth connective tissue that supports joint motion. Natural cartilage is created by specialized cells that generate large amounts of structural proteins to weave a tough support material called extracellular matrix. Lacking blood vessels, cartilage has limited capability to heal from arthritis, sports injuries or other defects. Damage can be treated with drugs or joint replacement but results can be imperfect. Engineered tissue is used in some medical treatments but is not yet a routine alternative to metal or plastic joint replacements. The NIST bioreactor gives researchers a noninvasive way to monitor important structural changes in developing tissue.

The NIST/CU bioreactor can fit inside a standard incubator, which controls temperature and acidity in the growth environment. The bioreactor applies force to stimulate five small cubes of cartilage cells embedded in water-based gels. The mechanical force mimics the
'/>"/>

Contact: Laura Ost
laura.ost@nist.gov
303-497-4880
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Bats, dolphins, and mole rats inspire advances in ultrasound technology
2. Space research gives birth to new ultrasound tools for health care in orbit, on Earth
3. Researcher to present discoveries on medical uses of ultrasound to Londons Royal Society
4. Researcher to present discoveries on medical uses of ultrasound to London’s Royal Society
5. Author predicts widespread acceptance of pocket-sized ultrasound machines
6. Undergraduates low-cost ultrasound system wins Gates Foundation grant
7. Ultrasound pioneer receives highest award in engineering profession
8. National Science Foundation Fellow uses ultrasound to research bog turtles
9. Ultrasound imaging now possible with a smartphone
10. Ultrasound shown to exert remote control of brain circuits
11. BWH researchers develop a vaccine prototype stronger than traditional vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
(Date:4/21/2015)... Canada , April 21, 2015 ... and evolving government policies are boosting access control systems ... According to a recently published report by ... Opportunities, 2020 ", the access control systems market in ... nearly USD1.2 billion by 2020.The access control systems market ...
(Date:4/20/2015)... 2015 Huntington Memorial Hospital is the first ... new miniaturized, wireless monitoring sensor to manage heart failure ... only FDA-approved heart failure monitoring device that has been ... physicians to manage heart failure. The CardioMEMS ... the pulmonary artery (PA) during a non-surgical procedure to ...
(Date:4/20/2015)... The announcement comes as demand ... Management (GRM), Ireland,s foremost records management ... built up an impressive track record of clients within the ... the records management sector in Dubai . ... staffbase and employ a further eight staff members at its ...
Breaking Biology News(10 mins):Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... Chemical Society (ACS) Weekly PressPac from the Office of ... journals and Chemical & Engineering News ., Please ... as the source for this information.` PressPac Archive: ... New tests: Marijuana damages DNA and may ...
... New Zealand researchers have accelerated research into Multiple Sclerosis ... help to unravel the causes of MS and other ... published today in the prestigious journal Nature Genetics ... remained a mystery. This discovery reveals important new insights ...
... Supply Chain Council -- Global Organization -- Begins in Houston ... and academic member, University of Houston ... College of Technology , ... first permanent Regional Center of Excellence for the U.S. Gulf Region. ...
Cached Biology News:American Chemical Society weekly presspac -- June 10, 2009 2American Chemical Society weekly presspac -- June 10, 2009 3American Chemical Society weekly presspac -- June 10, 2009 4American Chemical Society weekly presspac -- June 10, 2009 5American Chemical Society weekly presspac -- June 10, 2009 6American Chemical Society weekly presspac -- June 10, 2009 7Aussie and Kiwi researchers make double MS genetic discovery 2University of Houston Site of Regional Center of Excellence 2
(Date:4/25/2015)... Join us for a webinar at 12 ... Times using the Transcreener® ADP Assay , Register ... increasingly being incorporated into lead development efforts because longer ... increased therapeutic window and reduced side effects. Though ... such surface plasmon resonance, conjugation of drugs can affect ...
(Date:4/24/2015)... Top student social innovators from the ... universities, including UCSD and SDSU, will pitch their impact ... national and nonprofit companies for an opportunity to win ... Social Innovation Challenge 2015 . , The 2015 Social ... addressing a diverse range of issues including poverty, education, ...
(Date:4/24/2015)... AZ (PRWEB) April 24, 2015 The ... State University (ASU) have entered into an agreement to ... A memorandum of agreement signed by the universities will ... student success and other services particularly, though not exclusively, ... “We have complementary strengths and a similar set of ...
(Date:4/24/2015)... 2015 Leading Regenerative Veterinary Medicine ... allogeneic stem-cell product development program and changes its’ ... corporate strategic direction. , “I am extremely pleased ... cell development program has been kicked into high ... facility and hiring of our new Director of ...
Breaking Biology Technology:BellBrook Labs Webinar: Analyzing Kinase Inhibitor Residence Times using the Transcreener® ADP Assay 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 3South Dakota Mines, Arizona State University Pave Way for Cooperative Research 2Vet-Stem, Inc. Meets New Milestones and Changes Name to VetStem Biopharma 2
... DIEGO , May 11 Biomatrica, ... a solution-centric partnership program established with industry and ... storage and management of nucleic acids.  The Biomatrica ... for the development, testing, validation and use of ...
... May 11 Trans World Alloys (TWA) , one of the ... of their state-of-the-art, 40,000 square foot service center at 249 East Gardena Blvd., ... , (Photo: ... For the past ...
... Rice University researchers report using ultracentrifugation (UCF) to create ... team, led by Rice Professor Junichiro Kono and graduate ... small but significant step toward the dream of an ... quantum nanowire. The other, led by Rice Professor ...
Cached Biology Technology:Biomatrica Launches New Partnership Program - Biomatrica Connect(TM) 2Biomatrica Launches New Partnership Program - Biomatrica Connect(TM) 3Biomatrica Launches New Partnership Program - Biomatrica Connect(TM) 4Biomatrica Launches New Partnership Program - Biomatrica Connect(TM) 5Biomatrica Launches New Partnership Program - Biomatrica Connect(TM) 6Titanium and Aluminum Distributor, Trans World Alloys Relocates to Its Newly Built, State-of-the-Art Headquarters in Gardena, California 2Nano parfait a treat for scientists 2Nano parfait a treat for scientists 3
jub, ajuba homolog (Xenopus laevis)...
Recommend to use at up to 5000X dilutions for cell culture (e.g. Add 1 ul to 1 ml of culture medium.)...
Prepared in distilled water....
... Weight Markers, 37 kBq, 1 uCi. Carbon-14 ... of the sample on Western blots.The Rainbow-labeled ... migration in the gel and on the ... without Rainbow-labeling is 0.37-3.7 MBq/mg (10-100 uCi/mg) ...
Biology Products: