Navigation Links
Ultrasensitive biosensor promising for medical diagnostics
Date:5/15/2012

WEST LAFAYETTE, Ind. - Researchers have created an ultrasensitive biosensor that could open up new opportunities for early detection of cancer and "personalized medicine" tailored to the specific biochemistry of individual patients.

The device, which could be several hundred times more sensitive than other biosensors, combines the attributes of two distinctly different types of sensors, said Muhammad A. Alam, a Purdue University professor of electrical and computer engineering.

"Individually, both of these types of biosensors have limited sensitivity, but when you combine the two you get something that is better than either," he said.

Findings are detailed in a paper appearing Monday (May 14) in the Proceedings of the National Academy of Sciences. The paper was written by Purdue graduate student Ankit Jain, Alam and Pradeep R. Nair, a former Purdue doctoral student who is now a faculty member at the Indian Institute of Technology, Bombay.

The device ╨ called a Flexure-FET biosensor - combines a mechanical sensor, which identifies a biomolecule based on its mass or size, with an electrical sensor that identifies molecules based on their electrical charge. The new sensor detects both charged and uncharged biomolecules, allowing a broader range of applications than either type of sensor alone.

The sensor has two potential applications: personalized medicine, in which an inventory of proteins and DNA is recorded for individual patients to make more precise diagnostics and treatment decisions; and the early detection of cancer and other diseases.

In early cancer diagnostics, the sensor makes possible the detection of small quantities of DNA fragments and proteins deformed by cancer long before the disease is visible through imaging or other methods, Alam said.

The sensor's mechanical part is a vibrating cantilever, a sliver of silicon that resembles a tiny diving board. Located under
'/>"/>

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Orca ears inspire Stanford researchers to develop ultrasensitive undersea microphone
2. Carbon nanotubes form ultrasensitive biosensor to detect proteins
3. Ultrasensitive imaging method uses gold-silver nanocages
4. Biosensor illuminates compounds to aid fight against TB
5. Carnegie Mellon fluorescent biosensor reveals mechanism critical to immune system amplification
6. Improved characterization of nanoparticle clusters for EHS and biosensors research
7. New biosensor modelled on the immune system can detect, track and guide the clean-up of oil spills
8. New biosensor microchip could speed up drug development, Stanford researchers say
9. K-State chemists biosensor may improve food, water safety and cancer detection
10. Directed self-assembly of vertical nanotubes for biosensors, logic, nano-biofuel cells
11. Carnegie Mellon researchers create fluorescent biosensor to aid in drug development
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Ultrasensitive biosensor promising for medical diagnostics
(Date:6/30/2015)... To bolster its efforts and commitment to fighting cyber fraud, ... of two new team members. Dimitri ... Raviv will act as head of strategic alliances. These ... the most secure solutions for the enterprise market. ... a provider of security and management products, which was acquired ...
(Date:6/29/2015)... Research and Markets( http://www.researchandmarkets.com/research/zj7h4f/latin_america ... America Biomedical Sensors Market - Growth, Trends & Forecasts ... Latin America Biomedical Sensors market is estimated at $0.65 ... the period 2014-2020 The near future will ... formulation of each individual. These sensors can be set ...
(Date:6/25/2015)... 25, 2015 According to ... (Swipe & Area), Technology, Material (Optical Prism, Piezoelectric, ... Security & Others) & Geography - Global Forecast ... said market is expected to reach $14,500.07 Million ... Browse 76 market Tables and 109 ...
Breaking Biology News(10 mins):HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3Latin America Biomedical Sensors Market Report 2015-2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4
... transplanted trees must endure from the time they are ... stress factors can mean the difference between survival and ... dug prior to transport, the majority of the root ... initial stress, trees are typically taken to a loading ...
... University geoscientist who has stirred controversy with her studies ... the dinosaurs has compiled powerful new evidence asserting her ... at many sites in the United States, Mexico and ... a vast meteorite, were the more likely culprits in ...
... Barro Colorado Island in Panama, home of the Smithsonian ... been described as the best-studied piece of tropical real ... been a mecca for biologists for nearly 90 years, ... the jaguaruntil now. , Montclair State University zoologist ...
Cached Biology News:Tree survival skills 2Tree survival skills 3Princeton geoscientist offers new evidence that meteorite did not wipe out dinosaurs 2Princeton geoscientist offers new evidence that meteorite did not wipe out dinosaurs 3Princeton geoscientist offers new evidence that meteorite did not wipe out dinosaurs 4First jaguar photo taken at Smithsonian Research Station in Panama 2
(Date:7/1/2015)... InferMed , s ... will augment Elsevier ... olutions suite   Elsevier , a world-leading ... announced today the acquisition of  InferMed , a ... InferMed,s Arezzo technology supports clinicians in choosing the most ...
(Date:7/1/2015)... NEW YORK , July 1, 2015 /PRNewswire/ ... G ), a global leader in designing, ... the Aecus Innovation Award in recognition of their ... operational efficiencies in UCB,s global business services (GBS) ... acknowledge service providers and clients that work together ...
(Date:6/30/2015)... , June 30, 2015 /PRNewswire/ - Resverlogix ... of common shares of Resverlogix have approved the ... Eastern Capital Limited of 5,600,000 units at a ... Placement"), each unit being comprised of one common ... aggregate proceeds of approximately CAD$15 million; and (ii) ...
(Date:6/30/2015)...  Juniper Pharmaceuticals, Inc. (Nasdaq: JNP ), a ... address unmet medical needs in women,s health, today ... present at the Cantor Fitzgerald Inaugural Healthcare Conference ... 4:45 PM EDTLocation: , Le Parker Meridien Hotel, ... www.juniperpharma.com, under  ,Investor, or  click here ...
Breaking Biology Technology:Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 2UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 3UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 4UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 5Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 3Juniper Pharmaceuticals to Present at Cantor Fitzgerald Inaugural Healthcare Conference on July 8, 2015 2
... 29 Novavax, Inc.,(Nasdaq: NVAX ) today announced ... million by issuing common stock and warrants from its,existing ... certain current, new institutional shareholders and,affiliates of the Company ... of common stock and a warrant to purchase 0.5 ...
... Developed as an Antipsychotic Agent with Less Potential for ... Treatment-Associated Weight Gain and Metabolic Risks, SAN DIEGO, ... today announced that the United States Patent and,Trademark Office ... that would provide broad coverage for a pharmaceutical,composition of ...
... 29 Scimitar Equity, LLC issues a ... VOQP), entitled, "510k,Application Submitted for Xyfid(TM) and ... Share Price Appreciation.", This review is ... VioQuest Pharmaceuticals is a New Jersey-based biotechnology ...
Cached Biology Technology:Novavax Announces Pricing of $18 Million Financing of Common Stock and Warrants 2Novavax Announces Pricing of $18 Million Financing of Common Stock and Warrants 3Novavax Announces Pricing of $18 Million Financing of Common Stock and Warrants 4OREXIGEN(R) Therapeutics Receives Notice of Allowance for U.S. Patent Covering the Composition of Matter in OREX-003 2OREXIGEN(R) Therapeutics Receives Notice of Allowance for U.S. Patent Covering the Composition of Matter in OREX-003 3OREXIGEN(R) Therapeutics Receives Notice of Allowance for U.S. Patent Covering the Composition of Matter in OREX-003 4VioQuest Pharmaceuticals, Inc Valuation Upgrade Review Issued By Scimitar Equity, LLC 2
Hamster serum...
... Reactive Dye Pack, 12 x Cy5. ... optimized for microarray labeling.Higher reactivity Cy3 ... dye per vial, at > 75% ... dispensed, and packed in foil packs ...
Collected from sexually mature, mixed sex, mixed breed dogs. Serum from specific breeds available by request....
... EPS 301 Power Supply, 1. ... maximum.Constant voltage or constant current modes.Single-unit ... precision and reproducibility.Suitable for submarine, mini ... as well as semidry and mini ...
Biology Products: