Navigation Links
UVic biomedical engineer 'outsmarts' HIV
Date:12/10/2010

It is estimated that 38 million people worldwide are currently infected with HIV and that 4.1 million more are added each year. For scientists to design treatment therapies that are effective over the long-term it is essential to learn more about how the virus mutates and develops resistance to medications.

New, groundbreaking research by University of Victoria biomedical engineer Stephanie Willerth has significantly advanced the understanding of HIV and how to treat it.

"The virus mutates at a very high rate which is very problematic for HIV patients because the virus eventually develops resistance to medications,'' explains Willerth, a faculty member with UVic's Department of Mechanical Engineering and the Division of Medical Sciences.

Willerth and her team studied approximately 15,000 different versions of the virussomething that has never been done before. This information has allowed them to locate the specific genes of the virus that were resistant to the drugsknowledge that could ultimately help researchers develop more effective treatments for HIV.

Willerth says that the methods she used can be applied to other difficult-to-treat viruses such as swine flu, Ebola, influenza or even staph infections.

"To study all of these different versions we have to replicate them millions of times, especially when it comes to complex viruses like HIV," explains Willerth. "Because this research method requires a large amount of genetic material and there are obvious risks of duplicating highly contagious viruses, scientists have avoided doing this. Our research was unique because of the method we usedwe isolated the genetic material from HIV, so that it was no longer alive, before we replicated it."

After replicating the virus from a small sample obtained from a long-term HIV patient who had developed drug resistance to their treatment, Willerth and her team studied its genetic make-up using "next generation" DNA se
'/>"/>

Contact: Valerie Shore
vshore@uvic.ca
250-721-7641
University of Victoria
Source:Eurekalert

Page: 1 2

Related biology news :

1. UTHealth School of Biomedical Informatics professor to be inducted to AIMBE College of Fellows
2. Biomedical and health professionals converge in D.C. to absorb new findings in science of informatics
3. Fish gelatin: Ultra-high-tech biomedical uses ahead?
4. Plagiarism sleuths tackle full-text biomedical articles
5. UMMS biomedical researchers develop more reliable, less expensive synthetic graft material
6. Knome Awards Human Exome Sequencing and Analysis to Biomedical Researchers
7. LSU receives $15 million grant from NIH to build biomedical research pipeline for Louisiana
8. MARC Travel Awards announced for the 2010 Biomedical Engineering Society Annual Meeting
9. Warrior worms discovered in snails; UCSB scientists see possible biomedical applications
10. SPADnet, a new concept for biomedical imaging, gets funded
11. Drs. Erik De Clercq and Anthony S. Fauci win 2010 Dr. Paul Janssen Award for Biomedical Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... began on September 13, 2014. The fire is human-caused ... over 2,300 acres in size and is mostly being ... was calm Monday night due to higher humidity. ... and beginning to construct a fireline on the West and ... working on the fire: , 7 20-person Crews, 4 Hot ...
(Date:9/16/2014)... 10-km diameter chunk of rock hit the Yukatan peninsula near ... force of 100 teratons of TNT. It left a crater ... global earthquakes and volcanism are widely accepted to have wiped ... the mammals. But what happened to the plants on which ... from the University of Arizona reveals that the meteorite impact ...
(Date:9/16/2014)... week, its Government could face an uphill challenge in ... has revealed. , The University of Nottingham Shale Gas ... extraction in the UK since March 2012 and has ... the least supportive of fracking. , Professor Sarah O,Hara, ... Geography, said: "The clear move against shale gas extraction ...
Breaking Biology News(10 mins):Meteorite that doomed the dinosaurs helped the forests bloom 2Meteorite that doomed the dinosaurs helped the forests bloom 3Scottish people most sceptical on fracking, survey shows 2Scottish people most sceptical on fracking, survey shows 3
... study shows that personal values that people refuse to disavow, ... in the brain than those values that are willingly sold. ... whether it,s a strong religious belief, a national identity ... process," says Gregory Berns, director of the Center for Neuropolicy ...
... Doctors and researchers of Hospital del Mar and ... describing a new pharmacological resistance to cancer. This new ... (epidermal growth factor receptor) causing resistance to treatment using ... attacks the EGFR. The study proves that, both ...
... RIKEN SPring-8 Center in Harima, Japan have clarified the ... a bacterial enzyme that offers clues on the origins ... importance to fundamental science, the findings provide key insights ... greenhouse gas hundreds of times more potent than carbon ...
Cached Biology News:The price of your soul: How the brain decides whether to 'sell out' 2The price of your soul: How the brain decides whether to 'sell out' 3Identified a cause of resistance to colon cancer treatment 2New study sheds light on evolutionary origin of oxygen-based cellular respiration 2
(Date:9/17/2014)... SAN FRANCISCO, Calif. , Sept. 17, 2014 /PRNewswire/ ... ), a molecular diagnostics company pioneering the field of ... Hall to chief operating officer. Mr. Hall ... spearhead the company,s commercial entry into endocrinology. Since 2012, ... operations, as well as managed care and billing functions. ...
(Date:9/17/2014)... California , 17 de septiembre de ... ("la compañía"), principal proveedor mundial de soluciones ... las ciencias de la vida, anunció hoy ... de logística global con sede en Rótterdam, ... base de clientes Europa en rápido crecimiento. ...
(Date:9/17/2014)... Los Angeles, CA (PRWEB) September 17, 2014 ... GPS microchip for pets which will alert owners if their ... location using GPS from an implanted microchip in the pet’s body. ... implantable microchips for pets have been around for many ... GPS, and are not able to track a pet’s location or ...
(Date:9/17/2014)... MESSENGER has just celebrated its 10 year anniversary in ... of its latch valves, V27200-818, operating onboard this spacecraft. ... the planet Mercury. It is only the second spacecraft ... vast amount of information and images of the planet. ... that also include permanent magnets to maintain the valve ...
Breaking Biology Technology:Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 2Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 3Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 4Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 2Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 3Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 4Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 5Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 2Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 3
... Salk Institute is pleased to announce the appointment of ... Salk Institute Office of Technology Development. His appointment begins ... experience in academic technology transfer.  For over a decade ... Patent Foundation, where he led a broad expansion and ...
... Volcano Corporation (Nasdaq: VOLC ), a leading ... to enhance the diagnosis and treatment of coronary and ... to market the Eagle Eye® Platinum digital IVUS catheter ... 20th PCI Live Demonstration Course in Kurashiki, which starts ...
... 2011 Healthzone Limited (ASX: HZL; OTCQX: HLTZY) announced ... The Trout Group LLC ("the Trout Group"), a leading ... Trout Group will provide investor relations services for Healthzone ... With more than 60 current clients, the Trout Group ...
Cached Biology Technology:Salk Welcomes National Leader in Academic Technology Transfer 2Volcano Announces the Introduction of the Eagle Eye® Platinum Digital IVUS Catheter at the 20th PCI Live Demonstration Course in Kurashiki 2Volcano Announces the Introduction of the Eagle Eye® Platinum Digital IVUS Catheter at the 20th PCI Live Demonstration Course in Kurashiki 3Healthzone Limited Engages The Trout Group for Investor Relations Services 2
... Immunogen: Fusion protein derived from human ... (atypical PKC isotype-specific interacting protein/ partitioning ... related to the protease-activated-receptors also called ... (positive controls: Caco-2 MDCK A6 cell ...
For use with SSP products or any application requiring agarose gel separation • Multiple formats available to meet various throughput needs • Includes replacement parts for each un...
Request Info...
Human RUNX2/CBFA1 MAb (Clone 232902)...
Biology Products: