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UV exposure found to lower folate levels in young women

Women who are pregnant or trying to fall pregnant and taking a folic acid supplement may be at risk of reducing their folate benefit through sun exposure, a new QUT study has warned.

In a paper titled Exposure to solar ultraviolet radiation is associated with decreased folate status in women of childbearing age, published in the Journal of Photochemistry and Photobiology B:Biology, QUT researchers found UV exposure significantly depleted folate levels.

Professor Michael Kimlin and Dr David Borradale, from QUT's AusSun Research Lab, said the study of 45 young healthy women in Brisbane aged 18 to 47, showed high rates of sun exposure accounted up to a 20 per cent reduction in folate levels.

"This is concerning as the benefits of folic acid are well-known, with health professionals urging young women to take a folic acid supplement prior to and during pregnancy," Professor Kimlin said.

"Folate has been found to reduce miscarriage and neural tube defects such as spina bifida in unborn babies. The NHMRC recommends pregnant women or those planning a pregnancy take 500 micrograms a day."

Professor Kimlin said the study, which was the first to investigate the effects of sun exposure on folate levels in women of childbearing age, found women who had high levels of sun exposure had folate levels below those recommended for women considering pregnancy.

"The women at risk were those who were outside during the most UV intense time of the day, between 10am and 3pm, with little sun protection," Professor Kimlin said.

"These were the women who had the highest levels of sun exposure and the lowest levels of folate, whilst not deficient in folate, they were on the lower side of normal."

Dr Borradale said in showing the link between UV exposure and folate depletion, further research including a controlled clinical trial was needed.

"We are not telling women to stop taking folate supplements, but rather urging women to talk to their doctor about their folate levels and the importance of folate in their diet, especially those who are planning a pregnancy," Dr Borradale said.

"The results of this study reinforce the need for adequate folate levels prior to and during pregnancy."


Contact: Sandra Hutchinson
Queensland University of Technology

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