Navigation Links
UTMB study discovers cause of many preterm births
Date:5/13/2014

A new study by researchers at the University of Texas Medical Branch at Galveston is the first to show that premature aging of the placenta due to oxidative stress is the cause of many preterm births. The study appears today in the American Journal of Pathology.

Researchers took fetal membranes, exposed them to oxidative stress in a lab setting (specifically cigarette smoke extract) and examined whether it caused rapid aging of the placental tissue. It did.

Oxidative stress factors include environmental toxins and pollution and are an inevitable component of normal living. However, other factors such as smoking and drinking, high body mass index, poor nutrition and infection could be avoided.

Antioxidants in the body control any damage caused by oxidative stress. But when oxidative stress becomes overwhelming, it can trigger premature placental aging, which can result in preterm birth.

According to the researchers, antioxidant supplements during pregnancy have failed to reduce preterm births because the mechanisms of oxidative stress damage are still unclear.

"This is the first study to look at and prove that oxidative stress induces senescence, or aging, in human fetal cells," said Dr. Ramkumar Menon, an assistant professor in the UTMB Department of Obstetrics and Gynecology and lead researcher on the study. "With more than 15 million pregnancies worldwide ending in preterm births, we can now move forward in discovering how this information may lead to better intervention strategies to reduce the risk of preterm birth."

Previous studies suggested that infection is the major cause of preterm premature rupture of the membranes (pPROM, or breaking of the water bag during pregnancy), for which antibiotics are standard intervention.

However, UTMB researchers discovered that interventions such as antibiotics and antioxidants have not been successful in preventing preterm deliveries. This study provides evidence that there are other factors out there that the medical community should look for when that are causing spontaneous births, said Menon.


'/>"/>

Contact: Kristen Hensley
k.hensley@utmb.edu
409-772-8772
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Law that regulates shark fishery is too liberal: UBC study
3. New study will help protect vulnerable birds from impacts of climate change
4. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
5. BYU study: Using a gun in bear encounters doesnt make you safer
6. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
7. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
8. Crystal structure of archael chromatin clarified in new study
9. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
10. University of Houston study shows BP oil spill hurt marshes, but recovery possible
11. Study demonstrates cells can acquire new functions through transcriptional regulatory network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by Solution ... Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to 2022", ... 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at a ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 2017 Research and Markets has announced the ... to their offering. ... eye tracking market to grow at a CAGR of 30.37% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... launched Rosalind™, the first-ever genomics analysis platform specifically designed for life science ... in honor of pioneering researcher Rosalind Franklin, who made a major contribution ...
(Date:10/11/2017)... CA, USA (PRWEB) , ... October 11, 2017 , ... ... to take place on 7th and 8th June 2018 in San Francisco, CA. The ... influencers as well as several distinguished CEOs, board directors and government officials from around ...
(Date:10/11/2017)... ... October 11, 2017 , ... Disappearing forests and increased emissions are the main ... people each year. Especially those living in larger cities are affected by air pollution ... of the most pollution-affected countries globally - decided to take action. , “I knew ...
(Date:10/10/2017)... , ... October 10, 2017 ... ... cancer-focused pharmaceutical company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing ... HPLN (Hybrid Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s ...
Breaking Biology Technology: