Navigation Links
UTMB scientists awarded NIH grant for lab-grown lung tissue project
Date:7/27/2012

University of Texas Medical Branch at Galveston researchers have been awarded a two-year, $1.25 million National Institutes of Health grant to develop a method of custom-growing human lung tissue to make a three-dimensional model for biomedical studies.

The lab-grown piece of lung, about the size of a dime, will form the core of a system intended to provide a powerful new option for testing new vaccines and drugs and studying disease processes in the lung.

"I'm so excited that the NIH is giving us this opportunity," said UTMB professor Joan Nichols, principal investigator on the project. "We've been working on tissue engineering for a long time, and developing this kind of model has always been one of our goals. These systems could really change the paradigm of what we do."

The NIH is also funding 16 other projects aimed at developing similar models using engineered human tissues, including those for the heart, liver, kidney, intestine and skin. Ultimately, the agency hopes to connect different tissue models together, in order to create a system that could simulate the combined responses of multiple organs.

Although animal models for disease and pharmaceutical testing have a long record of success, experimental models based on engineered human tissues would offer significant advantages to researchers, Nichols said.

"First, it's a human system, and while you can simulate human responses with animal models, it's never perfect," she said. "Second, it's easily managed, and it scales up easily, because having no animal care makes everything cheaper and easier. And if the thing you're testing is toxic, it's just cells you're not killing an animal."

According to Nichols, tissue-engineered models will also give researchers the ability to more easily conduct repeated observations in live tissue and apply advanced imaging techniques such as two-photon microscopy. They should also allow researchers to study diseases
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... crime unit designed to fight food fraud in ... being passed off as beef scientists from Germany ... describe their approach, which represents a vast improvement over ... Food Chemistry . , Hans-Ulrich Humpf and colleagues note ... But they also say that adding, for example, horse ...
(Date:9/16/2014)... of severe maternal morbidity amongst women in Australia ... new study published today (17 September) in ... . , Australians generally enjoy high standards of ... disparities exist, in particular between indigenous and non ... explore the independent impact of socioeconomic position on ...
(Date:9/16/2014)... The 36 Pit Fire began on September 13, 2014. ... It is currently over 2,300 acres in size and ... The 36 Pit Fire was calm Monday night due to ... establishing an anchor point and beginning to construct a fireline ... The following resources are working on the fire: , 7 ...
Breaking Biology News(10 mins):New study examines the impact of socioeconomic position & maternal morbidity in Australia 2New study examines the impact of socioeconomic position & maternal morbidity in Australia 3
... BROOK, NY, February 20, 2013As the nations of the ... trade in endangered sharks in early March, a team ... the oceanic whitetip shark regularly crosses international ... apex predator within their own maritime borders may therefore ...
... The University of Texas at Arlington are pioneering a new ... make liquid methanol fuel by using copper oxide nanowires and ... expensive than previous methods to convert the greenhouse gas associated ... interim associate vice president for research at UT Arlington and ...
... from 375 past teen participants in a Canadian biotechnology ... -- show a majority of respondents were influenced by ... offering a model for countries worldwide to advance their ... of 375 past participants by Bioscience Education Canada, which ...
Cached Biology News:New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies 2New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies 3Researchers say sunlight yields more efficient carbon dioxide to methanol model 2'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 2'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 3'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 4'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 5'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 6'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 7'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 8'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 9'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 10'Inspiring' teens with 'research virus': Expert-mentored bioscience contest proves a powerful vector 11
(Date:9/17/2014)... Shimadzu Scientific Instruments introduces ... which offers a powerful separation method for ... provides a new level of knowledge and ... to scientists analyzing pharmaceutical impurities, proteins, lipids, ... Comprehensive 2D-LC combines two independent separation modes ...
(Date:9/17/2014)... PA & Rockville, MD (PRWEB) September 17, 2014 ... won a Small Business Innovation Research (SBIR) grant to ... immunotherapy. The award will provide ITI with approximately $255,000 ... Tree nuts, a leading cause of food allergy, affect ... cause of anaphylaxis behind peanut allergy. Tree nut exposure ...
(Date:9/17/2014)... , Sept. 17, 2014 /PRNewswire/ - SQI Diagnostics ... that develops and commercializes proprietary technologies and products for ... have been approved for trading in the ... Trading is expected to commence on September 17, 2014 ... will continue to trade on the TSX Venture Exchange ...
(Date:9/17/2014)... Escape Alert, LLC . filed international patents ... alert owners if their pet has escaped and enable them to ... in the pet’s body. This is the first implantable microchip ... been around for many years, they are passive until read by ... a pet’s location or alert the owner that the pet has ...
Breaking Biology Technology:Shimadzu’s New Nexera-e Two Dimensional Comprehensive Liquid Chromatograph Empowers Laboratories to Separate Even the Most Complex Mixtures 2Immunomic Therapeutics Awarded SBIR Grant to Develop Multi-Nut Allergy Immunotherapy 2Immunomic Therapeutics Awarded SBIR Grant to Develop Multi-Nut Allergy Immunotherapy 3SQI Diagnostics to begin Trading on the OTCQX Marketplace in the United States 2SQI Diagnostics to begin Trading on the OTCQX Marketplace in the United States 3Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 2Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 3
... NIH funds human ... ... announced today that it is one of the recipients in a 4-year $1.95M grant from ... evaluate Cell Sense, the Company’s fluorocarbon-based magnetic resonance imaging (MRI) cell tracking reagent, for clinical ...
... vital in helping to save up to 90 per cent ... to scientists. The research team led by Durham ... the UK) looked at the effects of climate change on ... on the network of sites designated for them (termed Important ...
... N.J., June 1 BD (Becton, Dickinson and Company) (NYSE: BDX ), a ... conferences in June: , , Goldman Sachs 30th ... 11:40 a.m. EDT, ... 11, 2009, 10:00 a.m. EDT, , ...
Cached Biology Technology:Celsense, Inc Receives NIH Grant to Translate Cell Imaging Technology for Clinical Use 2Celsense, Inc Receives NIH Grant to Translate Cell Imaging Technology for Clinical Use 3Nature parks can save species as climate changes 2Nature parks can save species as climate changes 3
Mouse monoclonal [6G11] to Cytohesin 1 + 2 ( Abpromise for all tested applications)....
HNF-1 Purified Anti-Mouse, Anti-Rat, Anti-Rabbit, Anti-Human clone 2, Isotype Mouse IgG 1 , 50 µg Consult technical datasheet for details....
Recombinant Porcine IL-1 alpha/IL-1F1, CF...
... siSolutions siRNA Custom Synthesis ... effective duplex RNA to knockdown ... 21-mers (19 RNA base pairs ... recently-published 27-mers, or other lengths ...
Biology Products: