Navigation Links
UTMB scientist awarded $150,000 by March of Dimes
Date:4/20/2012

The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. The grant will support her research on congenital heart defects, the most common type of major birth defect.

"I'm honored and privileged to receive this prestigious award," Kuyumcu-Martinez said. "I'm very thankful to the March of Dimes, and I'm really excited to be able to pursue the research their generosity will make possible."

Kuyumcu-Martinez's lab studies the heart's development from its earliest embryonic stages to adulthood. That process is controlled by changes in the way genes behave, which are themselves guided by complex biochemical signals.

"Certain genes expressed in the embryonic heart are not expressed in the heart of a newborn, and gene expression changes again in the heart of an adult," she said. "Our specific proposal was to study one of the signaling pathways that regulate these changes and sends a signal to the cell to switch from embryonic gene expression to post-natal or neonatal gene expression."

If the signaling pathway in question known as the protein kinase C pathway transmits an improper signal, the result can be improper gene expression. For example, the genes of embryonic heart cells can begin behaving as though they were in adult heart cells, producing the wrong proteins for a developing embryonic heart and ultimately causing a heart defect.

The March of Dimes award will enable her to delve deeper into both the protein kinase C pathway and its interactions with genes, using cell-culture and transgenic mouse experiments to produce a much more complete understanding of this important part of the heart-defect picture.

"We really want to understand this process in a more detailed manner," Kuyumcu-Martinez said. "We're very happy that this grant is going to give us a chance to do
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientist plans to test for blood pressure genes affected by age
3. Scientists identify novel inhibitor of human microRNA
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. MU scientists go green with gold, distribute environmentally friendly nanoparticles
6. Scientists identify gene that may contribute to improved rice yield
7. Scientists discover why a mothers high-fat diet contributes to obesity in her children
8. MU scientists see how HIV matures into an infection
9. Earth scientists keep an eye on Texas
10. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
11. Scientists identify a molecule that coordinates the movement of cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/15/2015)... -- A new report [ 1 ... US consumers using mobile banking applications want their mobile devices ... voiceprint, instead of having to prove who they are with ... Identity   -   The Fusion of Financial Services, Mobile ... primary channel used by Gen X and Gen Y to ...
(Date:6/11/2015)... , June 11, 2015 Daon, ... announced today that its IdentityX Mobile Authentication Platform ... IDentity Online) Alliance is an industry consortium launched ... standards for simpler, stronger authentication.  In order to ... pass a rigorous series of tests that measure ...
(Date:6/9/2015)... , June 09, 2015 Research ... addition of the "Gesture Recognition & Touchless ... (Consumer Electronics, Automotive, & Others), Product (Biometric & ... to 2020" report to their offering. ... market is expected to reach $ 23.55 Billion ...
Breaking Biology News(10 mins):One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 2One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 4Daon's IdentityX Mobile Authentication Platform One of First Products to be Certified by FIDO Alliance 2Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2
... , Oct. 21, 2013   Arcturus Therapeutics, Inc. , an industry ... today announced it has secured $5 million in a Series A ... Canada , Japan and ... http://photos.prnewswire.com/prnh/20130531/MM24393LOGO ) The Series A funding, which comprised ...
... MA In a biological quirk that promises to ... potentially treating Fragile X syndrome, scientists at the University ... out a gene important for messenger RNA (mRNA) translation ... in a mouse model of a prevalent human neurological ...
... Jude Children,s Research Hospital scientists has linked an inherited ... developing a pediatric acute lymphoblastic leukemia (ALL) subtype that ... today in the online edition of the scientific journal ... found in the GATA3 gene. Researchers reported the high-risk ...
Cached Biology News:Arcturus Therapeutics Raises $5 Million in Series A Funding to Maintain its Momentum in Nominating Lead Clinical Candidate in 2014 2Arcturus Therapeutics Raises $5 Million in Series A Funding to Maintain its Momentum in Nominating Lead Clinical Candidate in 2014 32 genetic wrongs make a biochemical right 22 genetic wrongs make a biochemical right 32 genetic wrongs make a biochemical right 4Inherited gene variation tied to high-risk pediatric leukemia and greater risk of relapse 2Inherited gene variation tied to high-risk pediatric leukemia and greater risk of relapse 3
(Date:7/1/2015)... July 1, 2015  Axovant Sciences Ltd. (NYSE: ... the treatment of dementia, today announced that the ... 22 at 5:45 p.m. EDT following its presentation ... International Conference 2015 (AAIC). The ... , Dr. Lawrence Friedhoff , Chief Development ...
(Date:7/1/2015)... Indianapolis, IN (PRWEB) , ... July 01, 2015 , ... ... the 2015 BIO International Convention in Philadelphia, PA. , The presentation took ... milestones and outlined the plans for the development of APX3330 for the treatment of ...
(Date:6/30/2015)... ... June 30, 2015 , ... Students and faculty from Beijing ... half of “Integrative Biotechnology,” an applied biotechnology course team-taught by faculty members from ... combines students from both universities and is taught on both continents. , “Our ...
(Date:6/30/2015)... , June 30, 2015  Juniper Pharmaceuticals, ... focused on developing therapeutics that address unmet medical ... George Elston will present at the ... Wednesday, July 8, 2015Time: , 4:45 PM EDTLocation: ... (live & archive): , www.juniperpharma.com, under  ,Investor, ...
Breaking Biology Technology:Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2Rivier University and Beijing City University Academic and Cultural Exchanges Begin 2Juniper Pharmaceuticals to Present at Cantor Fitzgerald Inaugural Healthcare Conference on July 8, 2015 2
... ARUP Laboratories, pathologist, Ronald L. Weiss, MD, MBA, ... of American Pathologists at CAP ,11, the organization,s annual ... the CAP, the award honors members "who have made ... the specialty of pathology." (Logo: http://photos.prnewswire.com/prnh/20110915/SF69370LOGO ...
... BEACH, Fla., Nov. 9, 2011 Biotech developer Divine ... which has been expanding the topical hair-growth segment, is ... system, Polaris API Solution 9, to be supplied by ... With well-established materials like minoxidil sulfate, finasteride, alfatradiol, ...
... Nov. 9, 2011 Third Quarter Highlights ... Awarded $5.7 million contract from Department of Defense (DoD) for ... awarded PharmAthene 50% net profit split on worldwide sales of ... million in net profits Completed 1500L commercial scale-up and ...
Cached Biology Technology:ARUP Laboratories' Pathologist, Ronald L. Weiss, MD, Honored With Lifetime Achievement Award for Contributions to Patient Care and Pathology 2Divine Skin Rolls Out Polaris API Solution 9: A New Technology for Physicians 2Divine Skin Rolls Out Polaris API Solution 9: A New Technology for Physicians 3PharmAthene Reports Third Quarter 2011 Financial and Operating Results 2PharmAthene Reports Third Quarter 2011 Financial and Operating Results 3PharmAthene Reports Third Quarter 2011 Financial and Operating Results 4PharmAthene Reports Third Quarter 2011 Financial and Operating Results 5PharmAthene Reports Third Quarter 2011 Financial and Operating Results 6PharmAthene Reports Third Quarter 2011 Financial and Operating Results 7PharmAthene Reports Third Quarter 2011 Financial and Operating Results 8
Mouse monoclonal antibody raised against a partial recombinant ACTN4. NCBI Entrez Gene ID = ACTN4...
Rabbit polyclonal antibody to GluR2...
... can be used to test the crossreactivity ... sera that are commonly used as blocking ... spots for 19 different protein preparations on ... crossreactivity and species specificity, QC of purified ...
... array sample elements. , ,Includes: , DiscoverLight ... BSA in PBS (10X): 50 ml , ... , BupH Phosphate Buffered Saline: 8 packs ... ml ampules , SuperSignal West Pico Luminol Enhancer: 2 ...
Biology Products: