Navigation Links
UTMB scientist awarded $150,000 by March of Dimes
Date:4/20/2012

The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. The grant will support her research on congenital heart defects, the most common type of major birth defect.

"I'm honored and privileged to receive this prestigious award," Kuyumcu-Martinez said. "I'm very thankful to the March of Dimes, and I'm really excited to be able to pursue the research their generosity will make possible."

Kuyumcu-Martinez's lab studies the heart's development from its earliest embryonic stages to adulthood. That process is controlled by changes in the way genes behave, which are themselves guided by complex biochemical signals.

"Certain genes expressed in the embryonic heart are not expressed in the heart of a newborn, and gene expression changes again in the heart of an adult," she said. "Our specific proposal was to study one of the signaling pathways that regulate these changes and sends a signal to the cell to switch from embryonic gene expression to post-natal or neonatal gene expression."

If the signaling pathway in question known as the protein kinase C pathway transmits an improper signal, the result can be improper gene expression. For example, the genes of embryonic heart cells can begin behaving as though they were in adult heart cells, producing the wrong proteins for a developing embryonic heart and ultimately causing a heart defect.

The March of Dimes award will enable her to delve deeper into both the protein kinase C pathway and its interactions with genes, using cell-culture and transgenic mouse experiments to produce a much more complete understanding of this important part of the heart-defect picture.

"We really want to understand this process in a more detailed manner," Kuyumcu-Martinez said. "We're very happy that this grant is going to give us a chance to do that."


'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientist plans to test for blood pressure genes affected by age
3. Scientists identify novel inhibitor of human microRNA
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. MU scientists go green with gold, distribute environmentally friendly nanoparticles
6. Scientists identify gene that may contribute to improved rice yield
7. Scientists discover why a mothers high-fat diet contributes to obesity in her children
8. MU scientists see how HIV matures into an infection
9. Earth scientists keep an eye on Texas
10. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
11. Scientists identify a molecule that coordinates the movement of cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
(Date:3/30/2017)... , March 30, 2017 Trends, opportunities ... (physiological and behavioral), by technology (fingerprint, AFIS, iris recognition, ... recognition, and others), by end use industry (government and ... immigration, financial and banking, and others), and by region ... , Asia Pacific , and ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO ... Diego Rotary Club. The event entitled “Stem Cells and Their Regenerative ... attendees. Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. ...
(Date:10/10/2017)... SomaGenics announced the receipt of a Phase ... (Single Cell), expected to be the first commercially available ... from single cells using NGS methods. The NIH,s recent ... development of approaches to analyze the heterogeneity of cell ... for measuring levels of mRNAs in individual cells have ...
(Date:10/10/2017)... , ... October 10, 2017 , ... ... of 13 prestigious awards honoring scientists who have made outstanding ... a scheduled symposium during Pittcon 2018, the world’s leading conference and exposition for ...
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television series will ... American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global population estimates ... of how to continue to feed a growing nation. At the same time, many ...
Breaking Biology Technology: