Navigation Links
UTMB scientist awarded $150,000 by March of Dimes
Date:4/20/2012

The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. The grant will support her research on congenital heart defects, the most common type of major birth defect.

"I'm honored and privileged to receive this prestigious award," Kuyumcu-Martinez said. "I'm very thankful to the March of Dimes, and I'm really excited to be able to pursue the research their generosity will make possible."

Kuyumcu-Martinez's lab studies the heart's development from its earliest embryonic stages to adulthood. That process is controlled by changes in the way genes behave, which are themselves guided by complex biochemical signals.

"Certain genes expressed in the embryonic heart are not expressed in the heart of a newborn, and gene expression changes again in the heart of an adult," she said. "Our specific proposal was to study one of the signaling pathways that regulate these changes and sends a signal to the cell to switch from embryonic gene expression to post-natal or neonatal gene expression."

If the signaling pathway in question known as the protein kinase C pathway transmits an improper signal, the result can be improper gene expression. For example, the genes of embryonic heart cells can begin behaving as though they were in adult heart cells, producing the wrong proteins for a developing embryonic heart and ultimately causing a heart defect.

The March of Dimes award will enable her to delve deeper into both the protein kinase C pathway and its interactions with genes, using cell-culture and transgenic mouse experiments to produce a much more complete understanding of this important part of the heart-defect picture.

"We really want to understand this process in a more detailed manner," Kuyumcu-Martinez said. "We're very happy that this grant is going to give us a chance to do that."


'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientist plans to test for blood pressure genes affected by age
3. Scientists identify novel inhibitor of human microRNA
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. MU scientists go green with gold, distribute environmentally friendly nanoparticles
6. Scientists identify gene that may contribute to improved rice yield
7. Scientists discover why a mothers high-fat diet contributes to obesity in her children
8. MU scientists see how HIV matures into an infection
9. Earth scientists keep an eye on Texas
10. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
11. Scientists identify a molecule that coordinates the movement of cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2017)... , Feb. 8, 2017 About Voice Recognition ... to match it against a stored voiceprint template. ... pitch, cadence, and tone are compared to distinguish ... hardware installation, as most PCs already have a ... transactions. Voice recognition biometrics are most likely to ...
(Date:2/7/2017)... Minn. , Feb. 7, 2017   MedNet ... supports the entire spectrum of clinical research, is pleased ... iMedNet , its innovative, highly flexible and award ... iMedNet customers. iMedNet is a proven ... provides Electronic Data Capture (EDC), but also delivers an ...
(Date:2/3/2017)... A new independent identity strategy consultancy firm ... . Designed to fill a critical niche in technical ... partners Mark Crego and Janice Kephart ... identity expertise that span federal governments, the 9/11 Commission, ... combined expertise has a common theme born from a ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... CA (PRWEB) , ... February 24, 2017 , ... Delpor, ... a $224K grant from the National Institute of Mental Health (NIMH) for the further ... on Delpor’s PROZOR technology and is expected to deliver therapeutic levels of ...
(Date:2/24/2017)... -- Aethlon Medical, Inc. (Nasdaq: AEMD ), today ... CEO, Jim Joyce . In a ... Bill Gates warned world leaders that a ... weapons. Mr. Gates expressed his concern, which is also ... terrorists have access to the necessary tools to design ...
(Date:2/24/2017)... Feb. 24, 2017 China Cord Blood Corporation (NYSE: ... leading provider of cord blood collection, laboratory testing, hematopoietic ... announced its unaudited financial results for the third quarter ... December 31, 2016. Third Quarter of Fiscal ... quarter of fiscal 2017 increased by 18.6% to RMB200.9 ...
(Date:2/24/2017)... Feb. 24, 2017  VWR Corporation (NASDAQ: VWR), the leading ... and production customers, today reported its financial results for the ... Highlights: 4Q16 record quarterly net ... on an organic basis. 4Q16 ... organic basis, while the Americas net sales increased 2.5%, or ...
Breaking Biology Technology: