Navigation Links
UTMB scientist awarded $150,000 by March of Dimes
Date:4/20/2012

The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. The grant will support her research on congenital heart defects, the most common type of major birth defect.

"I'm honored and privileged to receive this prestigious award," Kuyumcu-Martinez said. "I'm very thankful to the March of Dimes, and I'm really excited to be able to pursue the research their generosity will make possible."

Kuyumcu-Martinez's lab studies the heart's development from its earliest embryonic stages to adulthood. That process is controlled by changes in the way genes behave, which are themselves guided by complex biochemical signals.

"Certain genes expressed in the embryonic heart are not expressed in the heart of a newborn, and gene expression changes again in the heart of an adult," she said. "Our specific proposal was to study one of the signaling pathways that regulate these changes and sends a signal to the cell to switch from embryonic gene expression to post-natal or neonatal gene expression."

If the signaling pathway in question known as the protein kinase C pathway transmits an improper signal, the result can be improper gene expression. For example, the genes of embryonic heart cells can begin behaving as though they were in adult heart cells, producing the wrong proteins for a developing embryonic heart and ultimately causing a heart defect.

The March of Dimes award will enable her to delve deeper into both the protein kinase C pathway and its interactions with genes, using cell-culture and transgenic mouse experiments to produce a much more complete understanding of this important part of the heart-defect picture.

"We really want to understand this process in a more detailed manner," Kuyumcu-Martinez said. "We're very happy that this grant is going to give us a chance to do that."


'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Scientist plans to test for blood pressure genes affected by age
3. Scientists identify novel inhibitor of human microRNA
4. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
5. MU scientists go green with gold, distribute environmentally friendly nanoparticles
6. Scientists identify gene that may contribute to improved rice yield
7. Scientists discover why a mothers high-fat diet contributes to obesity in her children
8. MU scientists see how HIV matures into an infection
9. Earth scientists keep an eye on Texas
10. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
11. Scientists identify a molecule that coordinates the movement of cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2016)... LONDON , Jan. 20, 2016 A ... positioned to directly benefit from the explosion in genomics ... from Howe Sound Research. A range of dynamic trends ... ...... - personalized medicine - pharmacogenomics - pathogen ... economies with large markets - greater understanding of the ...
(Date:1/20/2016)... SAN JOSE, Calif. , Jan. 20, 2016 ... leading developer of human interface solutions, today announced ... touch controller solution for wearables and small screen ... appliances such as printers. Supporting round and rectangular ... the S1423 offers excellent performance with moisture on ...
(Date:1/15/2016)... , Jan. 15, 2016 Recent publicized ... small to find new ways to ensure data security ... iOS and Android that ties ... biometrics, transforming it into a hardware authorization token. Customer ... swipe their fingerprint on their KodeKey enabled device to ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... -- Wellcentive today announced it has been selected by FamilyCare ... community care organization (CCO) with more than 130,000 ... and care management solutions and services. Wellcentive,s capabilities ... managers, analysts and care managers while providing insight ... members. Oregon . ...
(Date:2/11/2016)... , Feb. 11, 2016  Dovetail Genomics™ LLC today ... beta program for a planned metagenomic genome assembly service. ... company,s metagenomic genome assembly method in a talk on ... Biology & Technology conference in Orlando, Fla. ... highly complex datasets is difficult. Using its proprietary ...
(Date:2/11/2016)... WASHINGTON , Feb. 11, 2016   BioInformant ... strategic report, "Stem Cell Research Products, Opportunities, Tools, and ... 2020. ... specialize in the stem cell industry, BioInformant has more ... of the stem cell market, by stem cell type. ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... a new agreement with Bankok,Thailand-based Global Stem Cells Network (GSCN) to distribute exosome ... Latin American countries, including Mexico, Costa Rica, Dominican Republic, Colombia, Argentina, Nicaragua, Panama, ...
Breaking Biology Technology: