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UTMB researchers to be honored at 'Oscars of invention'
Date:10/18/2007

ts us look at the responses of a wide variety of individuals with a wide variety of genetic backgrounds.

At the heart of the device, Nichols and Cortiella said, is an artificial matrix patterned after the porous structure of human bone marrow. In a human being, bone marrow nurtures the white blood cells that fight infection. The artificial immune system mimics this by providing nutrients and special mixtures of proteins and growth factors that transform stem cells into different specific immune cell types.

Nichols and Cortiella performed their experimental work in small individual "bioreactors developed by NASA for microgravity studies. But when VaxDesign brings what it calls the MIMIC (Model Immune In vitro Construct) technology to market in the next few years, the system is expected to be fully automated and able to evaluate thousands of different vaccine and therapeutic products per week.

The R&D 100 award is really a recognition of all the people who worked on this project, from engineers to biochemists to chemists to stem-cell biologists to infectious-disease people, Cortiella said. Five years ago we started out with a general concept and then over time narrowed down to a very specific idea, and finally developed a marketable product. It didnt just come from any one individual or idea, and its really a testament to the exciting things you can do when you bring together many people from multiple fields to work on one thing.


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Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

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