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UT to develop fracture putty for traumatic leg injuries
Date:1/26/2009

ng the reconnection of separated bones and the replacement of missing bones."

Tasciotti said the fracture putty could one day be used to address injuries involving the spine, skull and facial bones. "The findings of this research could eventually benefit all the victims of any bone-related traumatic injury and reduce the number of wartime amputations in the military as well the civilian population," he said.

"The technology to be explored through this research presents the potential to revolutionize the treatment of bone fractures, both in civilian clinics and on the battlefield," said Rice University investigator Antonios Mikos, Ph.D., the J.W. Cox Professor in Bioengineering, professor of chemical and biomolecular engineering and the director of Rice's Center for Excellence in Tissue Engineering. He is collaborating on the project.

If the fracture putty works in an animal model, the next step would involve patients. "We have been in preliminary conversations with the U.S. Food and Drug Administration, and it appears that fracture putty may be classified as a combination product, with the primary mode of action being that of a drug," Ferrari said.

Ferrari's colleagues at the UT Health Science Center at Houston on the project include: Paul Simmons, Ph.D., director of the Centre for Stem Cell Research at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases; Mark Wong, D.D.S., associate professor and chairman of the Department of Oral and Maxillofacial Surgery at the University of Texas Dental Branch at Houston and professor in the Division of Oral and Maxillofacial Surgery at The University of Texas Medical School at Houston; Nagi Demian, M.D., D.D.S., assistant professor at the UT Dental Branch; Paolo Decuzzi, Ph.D., associate professor of health informatics at The University of Texas School of Health Information Sciences at Houston; and Milos Kojic, Ph.D., visiting professor of health inform
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Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston
Source:Eurekalert

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