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UT faculty members win American Heart Association awards for advancing research
Date:12/23/2008

in a disease condition referred to as arrhythmogenic right ventricular cardiomyopathy, which is an important cause of sudden cardiac death in the young, especially athletes. In this disease, which is a genetic disorder, excessive fat cells replace cardiac myocytes in the heart, particularly the right side of the heart. She and her colleagues showed that fat cells originate from the stem cells in the heart that through a unique mechanism convert to fat cells in the presence of genetic mutations.

" The Katz Award is the most prestigious award given to young investigators in basic cardiovascular research by the American Heart Association," said Ali Marian, M.D., professor and director of the Center for Cardiovascular Genetic Research at the IMM. "The work (of Lombardi) could lead to the development of new therapies aimed at preventing the cardiac stem cells from switching a muscle fate to a fat cell fate and therefore, prevention of this potentially deadly disease."

Lombardi received her medical degree and clinical training in internal medicine and cardiology at Federico II University of Naples, Italy. She joined Marian's research group in the IMM three years ago and earned a doctorate in clinical physiopathology and experimental medicine from Federico II University of Naples during this period.


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Contact: Robert Cahill
Robert.Cahill@hotmail.com
713-500-3042
University of Texas Health Science Center at Houston
Source:Eurekalert

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