Navigation Links
UT Southwestern secures $5 million NIH grant for lupus research
Date:12/18/2007

DALLAS Dec. 19, 2007 The division of rheumatic diseases in the Department of Internal Medicine at UT Southwestern Medical Center has been awarded a five-year, $5 million grant from the National Institutes of Health to fund the Center of Research Translation, which will investigate the autoimmune disease systemic lupus erythematosus (SLE).

There are a limited number of these centers around the country, so this is a major accomplishment for UT Southwestern, said Dr. David Karp, chief of rheumatic diseases. This is a field in which UT Southwestern has had a leadership role for more than 50 years. We are proud to be continuing that tradition by building on our laboratory research findings and turning them into new ways to help patients with lupus and other autoimmune diseases.

Under principal investigators Drs. Chandra Mohan and Nancy Olsen, the project brings together UT Southwestern researchers from the departments of Immunology, of Microbiology and of Clinical Sciences, along with researchers from the Baylor Institute of Immunological Research.

Lupus research brings together all of these researchers on a regular basis, Dr. Mohan said. Although weve been interacting and collaborating on different projects for several years, this is the first time our collective research has been formally funded by a center grant. The overarching theme of this research is to translate our findings from basic research in mice to human SLE.

The scientists are divided into four interconnected research groups focused on key aspects of SLE development.

Dr. Mohan, professor of internal medicine, together with Dr. Anne Satterthwaite, assistant professor of internal medicine, will head a group focusing on why B-cells start to attack the body in SLE patients.

Overseeing a group working to identify the specific features that mark progression of the disease in SLE patients are Dr. Olsen, professor of internal medicine, and Dr. Karp.

Dr. Edward Wakeland, chairman of immunology and director of the Center for Basic Research in Molecular Immunology, will head a team investigating how a cluster of genes called the SLAM/CD contributes to SLE.

The fourth group, from the Baylor institute, will work to understand how dendritic cells and B-cells interact and shape human SLE.

Other UT Southwestern researchers involved in the Center of Research Translation are Dr. Quan Li, assistant professor of immunology, and Dr. Laurie Davis, associate professor of internal medicine.


'/>"/>

Contact: Erin Prather Stafford
erin.pratherstafford@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center  
Source:Eurekalert

Related biology news :

1. UT Southwestern researchers identify hundreds of genes controlling female fertility
2. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
3. Life-saving clean water project secures $13M from Bill & Melinda Gates Foundation
4. New study finds biodiversity conservation secures ecosystem services for people
5. Structure of 450 million year old protein reveals evolutions steps
6. First orchid fossil puts showy blooms at some 80 million years old
7. SyntheMed Completes $2.8 Million Equity Financing
8. Rutgers Genetics receives $7.8 million for autism research
9. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
10. UD leads $5.3-million research project on rice epigenetics
11. Rutgers high school outreach gets $3 million boost from NSF
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UT Southwestern secures $5 million NIH grant for lupus research
(Date:3/9/2017)... MOUNTAIN VIEW, Calif. , March 9, 2017 ... and 23andMe , the leading personal genetics company, ... Zipongo can now provide customers with personalized nutrition plans ... and biometrics, but also genetic markers impacting how their ... Zipongo,s personalized food decision support platform uses biometrics such ...
(Date:3/7/2017)...   HireVue , the leading provider of video ... best talent, faster, today announced the additions of ... Diana Kucer as Chief Marketing Officer (CMO). ... poised to drive continued growth in the company,s new ... record bookings in 2017. "Companies worldwide turn ...
(Date:3/2/2017)... Summary This report provides all the ... interests and activities since 2010. ... Read the full report: http://www.reportlinker.com/p03605615-summary/view-report.html ... report provides an in-depth insight into the partnering activity of ... On demand company reports are prepared upon purchase to ensure ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... 24, 2017 Agenus Inc. (NASDAQ: AGEN), an ... and cancer vaccines, today announced participation at the following ... William Blair and Maidstone Life Sciences conference "Cancer Immunotherapy ... New York, NY . Agenus will ... at 9:40 am: Robert B. Stein , M.D., ...
(Date:3/23/2017)... Mar 23, 2017 Research and Markets ... Markets" report to their offering. ... The Global Market for ... in 2016 at a CAGR of 8.9%, ... non-energetic bioproducts into seven major product segments: bio-derived chemicals, biofuels, ...
(Date:3/23/2017)...  GlobeImmune, Inc. today announced it has entered into ... shares of its common stock to NantCell, Inc., a ... the sale of its common stock, NantCell has agreed ... GlobeImmune 200,000 shares, an estimated $2.0 million in value, ... pleased to enter into this strategic agreement with NantCell," ...
(Date:3/23/2017)... March 23, 2017 Kineta, Inc., a ... novel therapies in immuno-oncology, today announced the discovery ... molecule compounds that activate interferon response factor 3 ... demonstrate immune-mediated tumor regression in a murine colon ... who demonstrated complete tumor regression to initial drug ...
Breaking Biology Technology: