Navigation Links
UT Southwestern secures $5 million NIH grant for lupus research
Date:12/18/2007

DALLAS Dec. 19, 2007 The division of rheumatic diseases in the Department of Internal Medicine at UT Southwestern Medical Center has been awarded a five-year, $5 million grant from the National Institutes of Health to fund the Center of Research Translation, which will investigate the autoimmune disease systemic lupus erythematosus (SLE).

There are a limited number of these centers around the country, so this is a major accomplishment for UT Southwestern, said Dr. David Karp, chief of rheumatic diseases. This is a field in which UT Southwestern has had a leadership role for more than 50 years. We are proud to be continuing that tradition by building on our laboratory research findings and turning them into new ways to help patients with lupus and other autoimmune diseases.

Under principal investigators Drs. Chandra Mohan and Nancy Olsen, the project brings together UT Southwestern researchers from the departments of Immunology, of Microbiology and of Clinical Sciences, along with researchers from the Baylor Institute of Immunological Research.

Lupus research brings together all of these researchers on a regular basis, Dr. Mohan said. Although weve been interacting and collaborating on different projects for several years, this is the first time our collective research has been formally funded by a center grant. The overarching theme of this research is to translate our findings from basic research in mice to human SLE.

The scientists are divided into four interconnected research groups focused on key aspects of SLE development.

Dr. Mohan, professor of internal medicine, together with Dr. Anne Satterthwaite, assistant professor of internal medicine, will head a group focusing on why B-cells start to attack the body in SLE patients.

Overseeing a group working to identify the specific features that mark progression of the disease in SLE patients are Dr. Olsen, professor of internal medicine, and Dr. Karp.

Dr. Edward Wakeland, chairman of immunology and director of the Center for Basic Research in Molecular Immunology, will head a team investigating how a cluster of genes called the SLAM/CD contributes to SLE.

The fourth group, from the Baylor institute, will work to understand how dendritic cells and B-cells interact and shape human SLE.

Other UT Southwestern researchers involved in the Center of Research Translation are Dr. Quan Li, assistant professor of immunology, and Dr. Laurie Davis, associate professor of internal medicine.


'/>"/>

Contact: Erin Prather Stafford
erin.pratherstafford@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center  
Source:Eurekalert

Related biology news :

1. UT Southwestern researchers identify hundreds of genes controlling female fertility
2. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
3. Life-saving clean water project secures $13M from Bill & Melinda Gates Foundation
4. New study finds biodiversity conservation secures ecosystem services for people
5. Structure of 450 million year old protein reveals evolutions steps
6. First orchid fossil puts showy blooms at some 80 million years old
7. SyntheMed Completes $2.8 Million Equity Financing
8. Rutgers Genetics receives $7.8 million for autism research
9. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
10. UD leads $5.3-million research project on rice epigenetics
11. Rutgers high school outreach gets $3 million boost from NSF
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UT Southwestern secures $5 million NIH grant for lupus research
(Date:4/15/2016)... , April 15, 2016  A new partnership ... more accurate underwriting decisions in a fraction of ... competitively priced and high-value life insurance policies to ... With Force Diagnostics, rapid testing (A1C, ... data readings (blood pressure, weight, pulse, BMI, and ...
(Date:4/13/2016)... CHICAGO , April 13, 2016  IMPOWER physicians ... are setting a new clinical standard in telehealth ... By leveraging the higi platform, IMPOWER patients can ... weight, pulse and body mass index, and, when they ... quick and convenient visit to a local retail location ...
(Date:3/29/2016)... , March 29, 2016 ... "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are pleased to ... ink used in a variety of writing instruments, ensuring ... of originally created collectibles from athletes on LegacyXChange will ... analysis of the DNA. Bill Bollander ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita ... miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject of ... now. , Diagnostic biomarkers are signposts in the blood, lung fluid or tissue ...
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
Breaking Biology Technology: