Navigation Links
UT Southwestern researchers identify molecule that helps the sleep-deprived to mentally rebound
Date:2/23/2009

of the animals. The mice also traveled a maze with eight paths, each with a piece of chocolate at the end of it.

Electronic measurements showed that, unlike normal mice, the mice lacking the adenosine receptor could not increase the intensity of their slow-wave activity in response to the sleep deprivation. Under normal sleep conditions both the normal and mutant mice were almost error-free on the maze test. However, when sleep-deprived, the engineered mice made significantly more errors on the maze test than their normal counterparts. This type of skills test represents the human equivalent of the attention and working memory needed to multitask or build on tasks already done, such as being given a phone number, reaching for a pen to write it down and recalling the number, said Dr. Greene.

Linking the lack of functioning adenosine receptors to depressed normal SWA rebound response might aid in developing treatments for people with sleep-related cognitive deficits, he said.

The research also further explains the effects of caffeine, which also "docks" to adenosine receptors, preventing the docking of adenosine and keeping the caffeine-drinker awake. Dr. Greene compared the study mice's behavior response on the maze test to how a person drinking a "permanent cup of coffee" might behave.

"They probably won't get the regular amount of slow-wave activity or deep sleep as they normally would," Dr. Greene said. "This is not to say that coffee is bad, but drinking it all the time or in the evening could affect your mental performance the next day."

The researchers next will investigate the relationship between sleep, adenosine and energy metabolism, a biological process in which adenosine plays a key role.


'/>"/>

Contact: LaKisha Ladson
lakisha.ladson@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. UT Southwestern researchers disrupt biochemical system involved in cancer, degenerative disease
2. Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover
3. UT Southwestern scientist honored among best in Texas research
4. UT Southwestern researchers identify gene linked to inherited form of fatal lung disease
5. Deranged calcium signaling contributes to neurological disorder, UT Southwestern researchers find
6. UT Southwestern researcher awarded Gates Foundation grant for novel vaccine development
7. RSV may hide in the lungs, lead to asthma, UT Southwestern researchers report
8. Waste from gut bacteria helps host control weight, UT Southwestern researchers report
9. Antidepressants need new nerve cells to be effective, UT Southwestern researchers find
10. Limiting fructose may boost weight loss, UT Southwestern researcher reports
11. UT Southwestern researchers identify new targets for RNAs that regulate genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... per year, carrying more than 284 million tons of cargo, ... dollars in toll fees for the Panama Canal Authority. Each ... of water are used from Gatun Lake, which is also ... in the isthmus. , However, the advent of very ... the ships at sea, has demanded change. The Panama Canal ...
(Date:5/23/2013)... the new mechanism by which estrogen suppresses lipid synthesis ... potential new approach toward treating certain liver diseases. ... believe they are changing long-held views in the field. ... the journal Science Signaling . , "The dogma ... been that only receptors located in the nucleus respond ...
(Date:5/23/2013)... for the overall health, development, and academic success ... in ensuring that all students have opportunities to ... of vigorous or moderate-intensity physical activity, says a ... Recent estimates suggest that only about half of ... better health and development. The report recommends ...
Breaking Biology News(10 mins):Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3UCI study reveals new mechanism for estrogen suppression of liver lipid synthesis 2Schools should provide opportunities for 60 minutes of daily physical activity to all students 2Schools should provide opportunities for 60 minutes of daily physical activity to all students 3
... D.C., February 8, 2012 Attention-deficit/hyperactivity disorder (ADHD) affects ... medications, such as methylphenidate and amphetamine products. A recent ... advised that all patients undergoing ADHD treatment be monitored ... Amidst growing concern over the risks of stimulant ...
... compounds in rice grains conducted by researchers at the ... identified 131 rice metabolites and clarified the genetic and ... a natural way to bioengineer improved rice grain varieties ... nutritional value of crops. As one of the ...
... Osteopathic Medicine student has been awarded the prestigious Ruth L. ... Health for his work on identifying the causes leading to ... college,s D.O.-Ph.D. program, will receive $65,000 over 21 months for ... and humbled by the opportunity," said Kousa of the award ...
Cached Biology News:Stimulant treatment for ADHD not associated with increased risk of cardiac events in youth 2New study sheds light on genetics of rice metabolism 2Osteopathic student garners national award for cleft palate research 2
(Date:5/23/2013)... 2013 Northwest Biotherapeutics (NASDAQ: NWBO ... personalized immune therapies for solid tumor cancers, announced ... year,s American Society Of Clinical Oncology (ASCO) meeting in ... role in immune therapy.  (Logo: http://photos.prnewswire.com/prnh/20110329/SF73084LOGO ... the pre-eminent conference focused on clinical treatment of cancer, ...
(Date:5/23/2013)... May 23, 2013  Verenium Corporation (Nasdaq: ... the development and commercialization of high-performance enzymes, today announced ... Officer, will present at two upcoming conferences. ... present at the Second Annual Marcum LLP Microcap Conference ... Hotel in New York City.  The presentation is scheduled ...
(Date:5/23/2013)... 2013 SynCardia Systems, Inc. ( http://www.syncardia.com ... Health Canada and CE (Europe) approved Total Artificial Heart, ... which boasts more than 380,000 visitors annually, is featuring ... by the Freedom® portable driver as part of its ... exhibitions of its kind. , “BodyWorks combines the ...
(Date:5/23/2013)... Bed bugs compromised Penn State. ... confirmed it. Meanwhile, My Cleaning Products offered complimentary samples of ... the pests without using harmful chemical elements. , Based ... the affected building was actually a dormitory , My ... made on May 13 and bed bug presence was confirmed ...
Breaking Biology Technology:NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 2NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 3Verenium To Present At Two Upcoming Conferences 2Verenium To Present At Two Upcoming Conferences 3SynCardia Total Artificial Heart Featured in $3 Million Exhibition at Glasgow Science Centre 2SynCardia Total Artificial Heart Featured in $3 Million Exhibition at Glasgow Science Centre 3Penn State Dorm Infested with Bed Bugs, My Cleaning Products Offers Complimentary Sample of Bed Bug Spray to Help Bed Bug Victims 2
... PAREXEL International,Corporation ("PAREXEL") (Nasdaq: PRXL ) notes ... ("ClinPhone" or the "Company"). Under the,United Kingdom Takeover Code, ... the Board of ClinPhone in relation to a potential,offer ... issued share capital of,ClinPhone. While that preliminary proposal was ...
... MIGENIX,Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for,infectious ... & CEO. Today,s CEO Message provides a discussion of the company,s,expected ... of catheter-related infections): - Phase ... NDA submission in H1/09 - ...
... Hcareers.com, the,leading hospitality industry online job ... of its reach to local regional candidates,through ... company,onTargetjobs. With the inclusion of RegionalHelpWanted.com,s network ... Hcareers now offers its,hospitality, restaurant and foodservice ...
Cached Biology Technology:Announcement in Relation to the Movement in the ClinPhone Share Price 2Announcement in Relation to the Movement in the ClinPhone Share Price 3Announcement in Relation to the Movement in the ClinPhone Share Price 4MIGENIX releases CEO message #22 2MIGENIX releases CEO message #22 3MIGENIX releases CEO message #22 4Hcareers.com Strengthens Local Market Candidate Reach Through RegionalHelpWanted.com Acquisition 2
Human Cystatin F MAb (Clone 292103)...
... is an inhibitor of ... concentration of inhibitor required ... must be determined empirically ... micromolar inhibitor is sufficient ...
Human RELT/TNFRSF19L Affinity Purified Polyclonal Ab...
Mouse NOV/CCN3 Affinity Purified Polyclonal Ab...
Biology Products: