Navigation Links
UT Southwestern researchers find protein that might be key to cutting cancer cells' blood supply
Date:5/11/2011

and is not found in the smooth muscle cells that make up the outside of the vessels.

The UT Southwestern scientists also discovered that Rasip1 and a protein binding partner are both required for blood vessels to form channels through which blood can flow, she said.

Most approaches to therapies aimed at blocking blood vessel formation have focused on growth factors that occur outside the cell rather than intrinsic cellular growth factors like Rasip1, Dr. Cleaver said.

"Although this is still a mouse study, we feel that future studies of Rasip1 and the molecular processes under its control hold great promise to provide tools and models for advancing clinical therapies aimed at blocking vessel formation in tumors," she said.

The researchers now plan to look for drugs that block Rasip1 in order to eventually develop strategies to stop the growth of functional blood vessels and starve cancerous tumors, she said.


'/>"/>

Contact: Deborah Wormser
deborah.wormser@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. UT Southwestern research reveals how cancer-driving enzyme works
2. Signaling path in brain may prevent that Im full message, UT Southwestern scientists discover
3. Team of scientists predicts continued death of forests in southwestern US due to climate change
4. UT Southwestern researchers uncover culprits in life-threatening clotting disorder
5. Alcohol consumers are becoming the norm, UT Southwestern analysis finds
6. UT Southwestern researchers find key step in bodys ability to make red blood cells
7. UT Southwestern researchers use novel sperm stem-cell technique to produce genetically modified rats
8. UT Southwestern researchers find mechanism that may stop E. coli from developing in cattle
9. UT Southwestern researchers identify key molecular step to fighting off viruses
10. UT Southwesterns BioCenter driving biotech, medical innovation in North Texas
11. New brain nerve cells key to stress resilience, UT Southwestern researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... Medicine have discovered a mechanism that is used to ... of blood typically associated with clotting, were discovered to ... it off from the rest of the body. The ... this week, provide the science community with a greater ... that platelets do participate in immunity, but now it,s ...
(Date:6/18/2013)... the Energy Department,s National Renewable Energy Laboratory (NREL), ... a paper describing a novel cellulose-degrading enzyme from ... commonly known as the gribble. , Gribbles ... unique ability to produce their own enzymes instead ... biomass they eat. New biomass-degrading enzymes from novel ...
(Date:6/18/2013)... environmental engineer has been awarded a $394,300 grant ... water quality and flow in the new facilities ... Kruzic, UT Arlington associate professor of civil engineering, ... add monochloramine to the water in an effort ... stations and pipelines. Adding monochloramine is widely practiced ...
Breaking Biology News(10 mins):Immunity mechanism discovered 2Novel enzyme from tiny gribble could prove a boon for biofuels research 2UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2
... or community taken to combat childhood obesity? The percentage ... 35 years. Local governments play a crucial role by shaping ... to find fresh fruits and vegetables, play outdoors, walk, and ... TO PREVENT CHILDHOOD OBESITY, a new report from the Institute ...
... air cargo scanning technology team has been awarded ... Prize for Outstanding Science in Support of Defence ... outstanding science and/or technology with the potential to ... security. Security and border protection are key ...
... Blacksburg, Va. -- After engineers and scientists at Virginia Tech, ... water, Michael Phelps may find he still has a few ... ,The remarkable ability of fish to maneuver in ... to accelerate in a seemingly effortless fashion has researchers wondering ...
Cached Biology News:Tackling childhood obesity at the local level -- IOM report releases Sept. 1 2NSF Emerging Frontiers' program supports development of smart materials based on study of fish 2NSF Emerging Frontiers' program supports development of smart materials based on study of fish 3
(Date:6/18/2013)... June 18, 2013 Earlier this year, Google ... platform. As this directly impacts the core component of ... one of the most sweeping updates since its inception in ... Technologies recently posted a very informative article on ... ‘must-have’ upgrade date for enhanced campaigns . Only ...
(Date:6/18/2013)... DC (PRWEB) June 18, 2013 On ... Services (CMS) released a final decision memorandum concluding ... to guide subsequent management of anti-tumor strategy, and ... collection. The National Oncological PET Registry (NOPR) was developed ... the first projects under the Coverage with Evidence Development ...
(Date:6/18/2013)... NY (PRWEB) June 18, 2013 ... software, today announces a new Fast-Track award from the ... integrated design-analysis environment (IDAE) for the nuclear power industry. ... halted for more than 30 years, but the United ... to remarkable gains in power plant utilization through improved ...
(Date:6/17/2013)... 2013  KaloBios Pharmaceuticals, Inc. (Nasdaq: KBIO ... Joseph as Chief Legal Officer.  Mr. Joseph brings ... and has worked in both public and private companies, ... (Logo: http://photos.prnewswire.com/prnh/20130225/MM66380LOGO ) "Don ... general counsel and senior executive and his knowledge and ...
Breaking Biology Technology:Core and More Technologies Helps Organizations Migrate to Google’s Enhanced Campaign Structure 2Core and More Technologies Helps Organizations Migrate to Google’s Enhanced Campaign Structure 3WMIS Welcomes CMS Decision: Expanding Coverage for FDG-PET and Ending NOPR Data 2WMIS Welcomes CMS Decision: Expanding Coverage for FDG-PET and Ending NOPR Data 3Kitware to Develop an Open-Source HPC Design-Analysis Environment for Nuclear Energy Research 2KaloBios Appoints Donald R. Joseph as Chief Legal Officer 2KaloBios Appoints Donald R. Joseph as Chief Legal Officer 3KaloBios Appoints Donald R. Joseph as Chief Legal Officer 4
... - Exploiting a novel technique called phase discontinuity, researchers at ... induced light rays to behave in a way that defies ... published this week in Science , has led to ... of a ray of light bouncing off a surface or ...
... /PRNewswire-iReach/ -- Advanced Technological Education Television (ATETV), an ... National Science Foundation , returns with 40 new videos just ... is a free Web video series featuring up to the ... and employment opportunities. The series debuted in 2009 and has ...
... 2011 An online library of cellular images freely ... celebrated its one-year anniversary on August 9, 2011 by ... favorite website. The Scientist announced the readers, ... from the judges. The Cell has more than 3,000 ...
Cached Biology Technology:From a flat mirror, designer light 2From a flat mirror, designer light 3New Videos Spotlight Science/Technology Careers and Educational Path To Secure Jobs in Them 2Free Online Library of Cell Images Wins 'The Labby' 2
Human Xg Affinity Purified Polyclonal Ab Keywords: Xg glycoprotein, hereditary hemorrhagic telangiectasia Protein Family: ...
in vitro Translation, Accessory Products...
...
Mouse Collagen IV...
Biology Products: