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UT Southwestern receives $42 million in Recovery Act stimulus funding
Date:11/12/2009

roving the nation's health, including projects focusing on cancer, heart disease, kidney disease, autism, neurodegenerative diseases and diabetes.

Some examples illustrate the anticipated impact of the grants:

  • Dr. Joseph Hill, chief of cardiology, "Functional Genomics of Complex Vascular Disease," $1,287,252. This grant will help expand research on the mechanisms of cardiovascular disease and includes support for a new, early-career faculty member. "More than 200 genetic associations with cardiovascular disease have been identified. Moving forward, we need to know how this information can be harnessed to predict who will develop heart disease and possibly develop new ways to intervene early in at-risk patients," Dr. Hill said.
  • Dr. Craig Powell, assistant professor of neurology and psychiatry, "Novel Genetic Animal Models of Autism," $549,500. The goal of this project is to understand better the genetic causes of human autism by using genetically engineered animal models of the disease. "This approach can be used to identify novel therapies for patients with autism," Dr. Powell said.
  • Dr. Elizabeth Maher, associate professor of internal medicine and neurology, "Genotype and Metabolic Phenotype in Glioblastoma," $1 million. Glioblastoma is the most common primary brain tumor and is considered one of the deadliest of human cancers. Dr. Maher and her colleagues in the Annette G. Strauss Center in Neuro-Oncology and in the Advanced Imaging Research Center focus on the metabolism of glioblastoma cells as a potential new target. "Our research will dissect the metabolic pathways that are abnormal in glioblastoma in a concerted effort to develop new therapies quickly," Dr. Maher said. "We anticipate that our discoveries will be applicable to other cancers as well."

Some of the Recovery Act grants awarded to UT Southwestern and other institutions fall under special priority categories designated by the NIH.

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Contact: Amanda Siegfried
amanda.siegfried@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

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