UT Public Health researchers find link to severe Staph ...(in the disease process. LukS-PV given th...)

Brown said, "The [vaccination] route and infection routes correlated with each other i.e., intranasally-immunized mice were better protected against pneumonia than subcutaneously vaccinated mice and subcutaneously-vaccinated mice were better protected against a skin infection than against pneumonia. This in part may be related to the type of immune response generated at the skin compared to the lung."

In addition, Brown and colleagues have examined the anti-PVL antibody responses in pediatric patients diagnosed with Staph infections compared to antibody responses to other USA300 virulence factors. The study found patients who had Staph infections caused by PVL-positive strains had a dominant response to the LukS and LukF proteins.

'/>"/>