Navigation Links
UT Arlington team's work could lead to earlier diagnosis, treatment of mental diseases
Date:8/13/2014

A computer science and engineering associate professor and her doctoral student graduate are using a genetic computer network inference model that eventually could predict whether a person will suffer from bipolar disorder, schizophrenia or another mental illness.

The findings are detailed in the paper "Inference of SNP-Gene Regulatory Networks by Integrating Gene Expressions and Genetic Perturbations," which was published in the June edition of Biomed Research International. The principal investigators were Jean Gao, an associate professor of computer science and engineering, and Dong-Chul Kim, who recently earned his doctorate in computer science and engineering from UT Arlington.

"We looked for the differences between our genetic computer network and the brain patterns of 130 patients from the University of Illinois," Gao said. "This work could lead to earlier diagnosis in the future and treatment for those patients suffering from bipolar disorder or schizophrenia. Early diagnosis allows doctors to provide timely treatments that may speed up aid to help affected patients."

The UT Arlington researchers teamed with Jiao Wang of the Beijing Genomics Institute at Wuhan, China; and Chunyu Liu, visiting associate professor at the University of Illinois Department of Psychiatry, on the project.

Gao said the findings also could lead to more individualized drug therapies for those patients in the early stages of mental illnesses.

"Our work will allow doctors to analyze a patient's genetic pattern and apply the appropriate levels of personalized therapy based on patient-specific data," Gao said.

One key to the research is designing single nucleotide polymorphism or SNP networks, researchers said.

"SNPs are regulators of genes," said Kim, who joins the University of Texas-Pan American this fall as an assistant professor. "Those SNPs visualize how individual genes will act. It gives us more of a complete picture."

The paper is a culmination of four years of work.

Khosrow Behbehani, dean of the College of Engineering, said the research merges the power of computer science and engineering, psychology and genetics.

"This research holds a lot of promise in the area of genetic expression," Behbehani said. "If successful, it opens up the possibility of applying the method to other pathological conditions."


'/>"/>

Contact: Herb Booth
hbooth@uta.edu
817-272-7075
University of Texas at Arlington
Source:Eurekalert  

Related biology news :

1. National herpetology society honors UT Arlington professor for discoveries
2. UT Arlington physics team demonstrates new power generation technique
3. National Academy of Inventors names four UT Arlington professors as charter fellows
4. UT Arlington engineer wins NSF award to support microfluidic analyses of tissue, cell samples
5. UT Arlington bioengineer to use hybrid imaging system to see deep tissue
6. UT Arlington engineer to search for bad algal blooms
7. UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline
8. UT Arlington engineer to design prototype that predicts flash flooding
9. 9 UT Arlington educators honored for teaching excellence
10. NSF awards to UT Arlington researchers will fuel sustainable solutions
11. UT Arlingtons Nguyen named American Heart Association fellow
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UT Arlington team's work could lead to earlier diagnosis, treatment of mental diseases
(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
(Date:4/11/2017)... Florida , April 11, 2017 ... a security technology company, announces the appointment of independent Directors ... Bendheim to its Board of Directors, furthering the company,s ... ... of NXT-ID, we look forward to their guidance and benefiting ...
(Date:4/5/2017)... April 5, 2017  The Allen Institute for Cell ... Explorer: a one-of-a-kind portal and dynamic digital window into ... data, the first application of deep learning to create ... cell lines and a growing suite of powerful tools. ... these and future publicly available resources created and shared ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... ... 2017 , ... Tunnell Consulting announced today that four of the ... Meeting and Expo , to be held October 29 through November 1 in San ... to advance patient therapies.” , The ISPE Annual Meeting and Expo will feature several ...
(Date:8/16/2017)... ... , ... While art and science are often thought of as two completely ... A Mesh Is Also a Snare, a group exhibition presented by the Philadelphia-based ... Gallery (EKG) on August 17 and run through September 30. An opening reception will ...
(Date:8/16/2017)...  This year,s edition of the Inc. 5000 features a now-familiar name: ... has made the list for the third year in a row. Now ... companies based on a set of quantitative metrics. In addition, BioPoint was ... in the Bay State . ... Inc. 5000 ...
(Date:8/15/2017)... ... August 15, 2017 , ... Kapstone Medical ... years of successes helping medical technology companies and inventors develop and safeguard their latest ... full-service national engineering firm with a portfolio of clients in the United States and ...
Breaking Biology Technology: