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USDA funded research leads to key discoveries in the pig genome
Date:11/16/2012

ation and scientific expertise throughout the sequencing process. ARS scientists at Beltsville, Md., working as part of the international team, contributed to the manual annotation the process of identifying genes and determining and describing what those genes do of more than 1,400 swine genes related to immunity. This work provided a basic description of the portion of the genome devoted to the animal's immune response. The ARS scientists' work revealed a high degree of similarity in the immunity genes of pigs and humans, a discovery that could contribute significantly toward the use of swine as a model in studies of both human and animal health and increase the potential of the pig as a biomedical model.

The ISGSC is led by Lawrence Schook, vice president for research at the University of Illinois; Professor Martien Groenen at Wageningen University in The Netherlands; and Professor Alan Archibald at the University of Edinburgh. Dr. Schook received grants for his work from NIFA. Gary Rohrer, Joan Lunney and Harry Dawson from ARS also contributed to the work done by ISGSC.

Much of the pioneering work done in support of the ISGSC has its roots in the National Research Support Project 8 (NRSP8) and NIFA's support of the U.S. Pig Genome Coordination program. The work of this program initial gene discovery and mapping and the sharing of reagents and mapping tools was crucial for the early work that led up to the sequencing of the pig genome.


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Contact: Jennifer Martin
jmartin@nifa.usda.gov
202-720-8188
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

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