Navigation Links
USDA funded research leads to key discoveries in the pig genome
Date:11/16/2012

WASHINGTON, Nov. 15, 2012 Research conducted and supported by the U.S. Department of Agriculture (USDA) has led to a new analysis of the pig genome, revealing new similarities between pigs and humans that could potentially advance biomedical research significantly. Additional findings from the study, reported today in the journal Nature, may also lead to better breeding strategies, improved pork production and improvements to human health. The research was conducted by a global team of scientists as part of the International Swine Genome Sequence Consortium (ISGSC).

"This new swine genome sequence analysis helps us understand the genetic mechanisms that enable high-quality pork production, feed efficiency and resistance to disease," said Sonny Ramaswamy, director of USDA's National Institute of Food and Agriculture. "This knowledge can ultimately help producers breed high-quality swine, lower production costs and improve sustainability. My congratulations to the International Swine Genome Sequence Consortium for this tremendous achievement."

The study found that the pig and its cousin the wild boar have much in common with humans. Researchers compared the genome of a common farm pig, Sus scrofa domesticus, with those of 10 wild boars all from different parts of Europe and Asia. Newly discovered details of the evolution Sus scrofa from the domestic pig first emerged in Southeast Asia and gradually migrated across Eurasia. The team found many significant genetic differences between the Asian and European wild boars, which separated from one another around one million years ago. Understanding the genetic origins of modern pigs is important in breeding efforts for disease resistance and growth efficiency.

Scientists from USDA's Agricultural Research Service (ARS) developed the first-ever genetic linkage map of the pig genome in 1994, laying the groundwork for subsequent sequencing efforts, and have provided collaboration and scientific expertise throughout the sequencing process. ARS scientists at Beltsville, Md., working as part of the international team, contributed to the manual annotation the process of identifying genes and determining and describing what those genes do of more than 1,400 swine genes related to immunity. This work provided a basic description of the portion of the genome devoted to the animal's immune response. The ARS scientists' work revealed a high degree of similarity in the immunity genes of pigs and humans, a discovery that could contribute significantly toward the use of swine as a model in studies of both human and animal health and increase the potential of the pig as a biomedical model.

The ISGSC is led by Lawrence Schook, vice president for research at the University of Illinois; Professor Martien Groenen at Wageningen University in The Netherlands; and Professor Alan Archibald at the University of Edinburgh. Dr. Schook received grants for his work from NIFA. Gary Rohrer, Joan Lunney and Harry Dawson from ARS also contributed to the work done by ISGSC.

Much of the pioneering work done in support of the ISGSC has its roots in the National Research Support Project 8 (NRSP8) and NIFA's support of the U.S. Pig Genome Coordination program. The work of this program initial gene discovery and mapping and the sharing of reagents and mapping tools was crucial for the early work that led up to the sequencing of the pig genome.


'/>"/>

Contact: Jennifer Martin
jmartin@nifa.usda.gov
202-720-8188
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Related biology news :

1. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
2. NIH-funded study examines use of mobile technology to improve diet and physical activity behavior
3. ONR-funded research takes flight in Popular Science article
4. ONR-funded young innovators recognized by President
5. NIH-funded researchers restore sense of smell in mice using genetic technique
6. NIH-funded genetic sequencing tool speeds drug discovery, disease diagnostics
7. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
8. Research reveals first evidence of hunting by prehistoric Ohioans
9. Diabetes Research Institute develops oxygen-generating biomaterial
10. APS issues new policy requiring identification of sex or gender in reporting scientific research
11. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/15/2016)... , June 15, 2016 ... report titled "Gesture Recognition Market by Application Market - Global Industry ... - 2024". According to the report, the  global gesture ... in 2015 and is estimated to grow at ... billion by 2024.  Increasing application of ...
(Date:6/2/2016)... , June 2, 2016 The Department ... has awarded the 44 million US Dollar project, for the ... Vehicle Plates including Personalization, Enrolment, and IT Infrastructure , ... in the production and implementation of Identity Management Solutions. Numerous ... however Decatur was selected for the ...
(Date:5/20/2016)... -- VoiceIt is excited to announce its new marketing ... working together, VoiceIt and VoicePass will offer an ... slightly different approaches to voice biometrics, collaboration between ... Both companies ... "This marketing and technology partnership allows VoiceIt ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking software ... State Crime Laboratory, has joined STACS DNA as a Field Application Specialist. , ... Tremblay, President and COO of STACS DNA. “In further expanding our capacity as a ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
(Date:6/23/2016)... Andrew D Zelenetz ... Published recently in Oncology ... touchONCOLOGY, Andrew D Zelenetz , discusses the ... is placing an increasing burden on healthcare systems ... With the patents on many biologics expiring, interest ...
(Date:6/23/2016)... CA (PRWEB) , ... June 23, 2016 , ... ... software, is exhibiting at the Pennsylvania Convention Center and will showcase its product’s ... conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical Trials ...
Breaking Biology Technology: