Navigation Links
UNC study helps clarify link between high-fat diet and type 2 diabetes
Date:4/11/2011

CHAPEL HILL, N.C. A diet high in saturated fat is a key contributor to type 2 diabetes, a major health threat worldwide. Several decades ago scientists noticed that people with type 2 diabetes have overly active immune responses, leaving their bodies rife with inflammatory chemicals.

In addition, people who acquire the disease are typically obese and are resistant to insulin, the hormone that removes sugar from the blood and stores it as energy.

For years no one has known exactly how the three characteristics are related. But a handful of studies suggest that they are inextricably linked.

New research from the University of North Carolina at Chapel Hill School of Medicine adds clarity to the connection. The study published online April 10 in the journal Nature Immunology finds that saturated fatty acids but not the unsaturated type can activate immune cells to produce an inflammatory protein, called interleukin-1beta.

"The cellular path that mediates fatty acid metabolism is also the one that causes interleukin-1beta production," says senior study co-author Jenny Y. Ting, PhD, William Kenan Rand Professor in the Department of Microbiology and Immunology.

"Interleukin-1beta then acts on tissues and organs such as the liver, muscle and fat (adipose) to turn off their response to insulin, making them insulin resistant. As a result, activation of this pathway by fatty acid can lead to insulin resistance and type 2 diabetes symptoms." Ting is also a member of the UNC Lineberger Comprehensive Cancer Center, and the UNC Inflammatory Diseases Institute.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina School of Medicine
Source:Eurekalert  

Page: 1

Related biology news :

1. Clinical study suggests estrogen levels and breast health can be altered
2. New genetic study helps to solve Darwins mystery about the ancient evolution of flowering plants
3. People control thoughts better when they see their brain activity: UBC study
4. Soy increases effectiveness of radiation at killing lung cancer, Wayne State study shows
5. Chimpanzees contagious yawning evidence of empathy, not just sleepiness, study shows
6. Chemical engineers at UCSB design molecular probe to study disease
7. Birds must choose between mating, migrating, study finds
8. Study finds link between chronic depression and accelerated immune cell aging
9. Drought-exposed leaves adversely affect soil nutrients, study shows
10. Economics, physics are roadblocks for mass-scale algae biodiesel production, study finds
11. Chimp, bonobo study sheds light on the social brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC study helps clarify link between high-fat diet and type 2 diabetes
(Date:1/22/2015)...   EyeLock, Inc. , a market leader of iris-based identity ... to the new role of Senior Vice President of ... of mobile platforms and wearable solutions for EyeLock,s technologies. Gerber ... the semiconductor industry to his role at EyeLock, with expertise ...
(Date:12/22/2014)...  NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ("NXT-ID" ... growing mobile commerce market, announces it has retained famous pickpocket, ... 2015 International CES debut of the Wocket™ biometric smart wallet.  ... the NXT-ID booth January 6th and 7 th , 2015, ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & ... http://photos.prnewswire.com/prnh/20130307/600769 ... introduced the fingerprint reading feature with the iPhone 5S. ...
Breaking Biology News(10 mins):EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2
... in Use, Including Large Scale, Election Enrollment, Retail, Financial, ... ... Demonstrated, WALL, N.J., Sept. 10 BIO-key International,Inc. (OTC ... safety, announced today that the company,is showcasing a variety of deployed ...
... have fully recovered from whaling, were once three to five ... report to be published September 10 in the Proceedings of ... more than 22,000 gray whales has successfully been brought back ... abundant whale on the North American west coast. But the ...
... plans to help health-conscious people better gauge what,s on ... Carol Boushey, an associate professor in the Department of ... a technique already in use by adding a strong ... that monitor eating habits by critiquing photos they send ...
Cached Biology News:BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo 2BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo 3Gray whales a fraction of historic levels, genetic research says 2Purdue researchers click nutrition with camera diet study 2
(Date:1/22/2015)... 2015   Cypher Genomics, Inc., the leading ... SQNM ), the leading molecular diagnostics company, ... noninvasive prenatal tests (NIPT). Through this agreement, Sequenom ... to advance analysis of clinically-relevant fetal sub-chromosomal variants ...
(Date:12/24/2014)... Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval application ... the use of Medtronic,s SynchroMed ® II implantable ... use with United Therapeutics, Remodulin ® (treprostinil) Injection ...
(Date:12/24/2014)... Missouri (PRWEB) December 23, 2014 GMO corn ... company, Syngenta, are in the process of being consolidated in ... is In Re: Syngenta AG MIR 162 Corn Litigation, MDL ... of Kansas. , Management of the Syngenta GMO corn multidistrict ...
(Date:12/24/2014)... The report provides basic information ... application and industry overview. This report also presents ... Production is separated by regions, technology and applications. ... downstream client survey, marketing channels, industry development trend ...
Breaking Biology Technology:Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2
... - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ: ONCY ... contract manufacturer, SAFC Pharma(R), a Division of Sigma-Aldrich Corporation, ... of REOLYSIN under cGMP conditions. This run is anticipated ... completed over the next several years as Oncolytics provides ...
... , , , , ... of the i-port(R) and a leader of injection port ... with Unomedical, a leading manufacturer of single use medical devices used ... http://www.newscom.com/cgi-bin/prnh/20090727/DA51373 ) , , The two companies ...
... RIVERSIDE, Calif. Graphene is nature,s thinnest elastic ... Its one-atom thickness, planar geometry, high current-carrying capacity ... further miniaturizing electronics through ultra-small devices and components ... of graphene,s intrinsic features is ripples, similar to ...
Cached Biology Technology:Oncolytics Biotech Inc. Successfully Completes 100-Litre cGMP Production of REOLYSIN(R) 2Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections 2Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections 3UCR scientists manipulate ripples in graphene, enabling strain-based graphene electronics 2UCR scientists manipulate ripples in graphene, enabling strain-based graphene electronics 3
Human Glypican 2 Biotinylated Affinity Purified PAb...
B2-Microgloulin...
... CTI Molecular Imaging's proprietary Focus™ detector technology, ... as the R4. The microPET Focus ... commerically avaiable PET scanner. Focus scanners ... any scinitallor based PETsystems. The combination ...
...
Biology Products: