UNC study: Scientists identify chemical compound that may stop deadly br...(have this mutation Xiong said. Even thou...)

Date:4/9/2009

have this mutation, Xiong said. Even though these two types of GBM have a similar end result, the tumor types develop in very different ways, and doctors will need very different treatments to stop them. The first author of the Science paper is Shimin Zhao, Ph.D., of Fudan University in Shanghai, China. Zhao and students in his lab made key contributions to the research, Xiong said. Those students, also authors on the paper, are Yan Lin, Wei Xu, Wenqing Jiang, Zhengyu Zha, Pu Wang, Wei Yu, Zhiqiang Li, Lingling Gong, Yingjie Peng, Jianping Ding and Qunying Lei.

Xiong and Guan helped develop the lab at Fudan University and supervise graduate student training and project development there.

Xiong and his colleagues are continuing studies of other effects of the IDH1 mutation and are developing a mouse model of secondary GBM that could be used to test the potential treatment.

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Contact: Dianne Shaw dgs@med.unc.edu 919-966-7834 University of North Carolina School of Medicine Source:Eurekalert

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