Navigation Links
UNC scientists win $1.6 million stimulus award to accelerate decoding of human genome
Date:10/15/2009

Ever since the first genome sequence was published in 2001, scientists have been working to figure out what the sequence means. An analogy is walking across a desert and finding a large book in a language you don't know, then trying to figure out what the book is saying.

"In the case of the human genome, the book is a blueprint to building cellsand ultimatelythe whole human. But we don't yet understand its language," said Morgan Giddings, Ph.D., associate professor of microbiology and immunology and of biomedical engineering at the University of North Carolina at Chapel Hill.

Giddings and UNC colleague Xian Chen, Ph.D., associate professor of biochemistry and biophysics, have been developing methods for decoding the human blueprint by studying the things the blueprint produces: proteins. They relate the proteins back to the blueprint itself, to further decode the language of the genome blueprint.

Giddings and Chen have been awarded a $1.6 million 2-year "Grand Opportunities" (GO) grant from the National Human Genome Research Institute to accelerate this research. Their effort will be part of a consortium of investigators studying the human genome blueprint, titled the "ENCyclopedia Of DNA Elements" (ENCODE). The consortium's overall goal is to assemble a comprehensive catalog of functional elements in the human genome.

With their GO grant, Giddings and Chen will generate, analyze, and release to the public large-scale data sets that allow linking of the protein products in cells to their genomic blueprints. According to Giddings, "this will significantly promote our understanding of the language of the human genome, enhancing efforts to solve pressing human health issues like heart disease and cancer by understanding how errors in the blueprint lead to disease, and how we might fix those errors."

Giddings is a member of the Carolina Center for Genome Sciences, and Chen is technology development director for the UNC Proteomics Core. The new grant will bring 4-6 new high-tech jobs to the Triangle.

NHGRI has awarded approximately $22 million of American Recovery and Reinvestment Act 2009 funds to support research aimed at identifying and understanding the genome's functional elements.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina School of Medicine
Source:Eurekalert  

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC scientists win $1.6 million stimulus award to accelerate decoding of human genome
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
(Date:4/19/2017)... York , April 19, 2017 ... as its vendor landscape is marked by the presence ... market is however held by five major players - ... Together these companies accounted for nearly 61% of the ... the leading companies in the global military biometrics market ...
(Date:4/18/2017)...  Socionext Inc., a global expert in SoC-based imaging and computing ... M820, which features the company,s hybrid codec technology. A demonstration utilizing ... Inc., will be showcased during the upcoming Medtec Japan at Tokyo ... Las Vegas Convention Center April 24-27. ... Click here for an image ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... Pa. , April 26, 2017  Genisphere ... delivery platform, has signed a collaborative and sponsored ... Dr. Silvia Muro . The overall goal ... and pharmacodynamics of various 3DNA designs and formulations ... involve targeting diseases of the vasculature as well ...
(Date:4/25/2017)... GREENVILLE, SC (PRWEB) , ... April 25, 2017 ... ... SC-based Piedmont Physical Medicine & Rehabilitation, P.A. , proudly announced today that ... will officially commence his duties on May 15, 2017. , Dr. Terzella completed ...
(Date:4/21/2017)... ... 2017 , ... The 2017 Colorado Manufacturing Awards celebrates Innovation ... and well as the first-year award for 2017 Manufacturing Women of the Year. ... by CompanyWeek and Manufacturers Edge, among other sponsors. , The Colorado Manufacturing ...
(Date:4/21/2017)... ... , ... Frederick Innovative Technology Center, Inc. (FITCI), a business ... start-ups, is hosting “Celebration Friday” (a festive gathering highlighting client success stories) and ... networking at 3:30 p.m. at FITCI’s 4539 Metropolitan Court location, off English Muffin ...
Breaking Biology Technology: