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UNC scientists teach enzyme to make synthetic heparin in more varieties
Date:11/25/2008

d is very inexpensive, but if we cannot control the supply chain, we cannot ensure the safety of the drug," Liu said. "I am working for the day when synthetic heparin can be brewed in large laboratories at a low cost."

There is also interest in heparin as a treatment for small-cell lung cancer, Liu said. Being able to produce customized versions of the heparin molecule using 2-O-sulfotransferase would allow researchers to emphasize the drug's potential anti-cancer properties. Heparin-like structures have also shown potential as treatments for arthritis, asthma and transplant rejection, among other conditions.


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Contact: Patric Lane
patric_lane@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

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