Navigation Links
UMass Medical School study points to genetic link in apnea of prematurity
Date:11/2/2010

WORCESTER, Mass. A potentially life-threatening challenge characterized by pauses in breathing that can last for more than 20 seconds, apnea of prematurity (AOP) affects more than 50 percent of premature infants and is almost universal in the smallest of preemies. Caused in part by an underdeveloped central nervous system that can't adequately regulate breathing outside of the womb, especially during sleep, AOP is not yet fully understood by scientists and remains a grave concern among neonatologists and parents alike. New research published in the October issue of Pediatrics by clinical scientists at the University of Massachusetts Medical School suggests that heredity may play a strong role in determining an infant's susceptibility to AOP and could lead to the development of more effective treatments and screening methods.

Because it causes gaps in breathing, AOP can lead to reduced oxygen levels and a slowed heart rate in premature infants, as well as permanent disabilities and long-term damage to internal organs. Requiring around-the-clock monitoring, infants with AOP often must be gently jostled or rubbed to encourage inhalation and continued breathing, but such activities wake the baby, depriving it of much needed sleep. In severe cases, pharmaceutical interventions, such as caffeine, may be required. While the permanent consequences of AOP and its treatments have yet to be fully studied, infants with AOP are more likely to have cognitive and behavior problems, and other long-term disabilities.

"AOP is a medical puzzle," said David Paydarfar, MD, professor of neurology and physiology at the University of Massachusetts Medical School. "Our research seeks to explain why there is so much variability in the incidence and severity of apnea in premature infants and why some infants outgrow the problem much sooner than others."

Elisabeth B. Salisbury, PhD, assistant professor of neurology, Paydarfar, and colleagues compared the rates of AOP in 2
'/>"/>

Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck
2. Imperial and NTUs new medical school aspires to be global health care role model
3. Plagiarism sleuths tackle full-text biomedical articles
4. UMMS biomedical researchers develop more reliable, less expensive synthetic graft material
5. Computational model of swimming fish could inspire design of robots or medical prosthetics
6. Knome Awards Human Exome Sequencing and Analysis to Biomedical Researchers
7. LSU receives $15 million grant from NIH to build biomedical research pipeline for Louisiana
8. MARC Travel Awards announced for the 2010 Biomedical Engineering Society Annual Meeting
9. Warrior worms discovered in snails; UCSB scientists see possible biomedical applications
10. SPADnet, a new concept for biomedical imaging, gets funded
11. Drs. Erik De Clercq and Anthony S. Fauci win 2010 Dr. Paul Janssen Award for Biomedical Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/12/2015)...  Securus Technologies, a leading provider of civil ... investigation, corrections and monitoring, announced the United States ... analyze and identify participants of a video visitation ... This system can: , Identify that ... sign-on process is actually the person participating in ...
(Date:6/9/2015)... Minn. , June 9, 2015   MedNet ... supports the entire spectrum of clinical research, will be ... eClinical technology platform at the 2015 Drug Information Association ... on June 15-17.  These presentations will include previews ... rolled out in the upcoming iMedNet 2015 ...
(Date:6/8/2015)... 8, 2015  The Secure Identity & ... of Troy Potter of L-3 National ... is a non-profit association that was established in ... and implementation of solutions that protect and secure ... Photo ...
Breaking Biology News(10 mins):Securus Announces Patent Issued for Authorized Presence Verification During Video Visitation 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 3Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 2Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 3Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 4Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 5
... With 900,000 assisted reproduction treatments annually such as ... to screen both partners before each treatment could lead ... figures do not include the additional overhead costs such ... have to carry on top of that. The new ...
... discovery in a laboratory at Oregon State University has apparently ... the energies of ancient Egyptians, the Han dynasty in China, ... blue pigment. Through much of recorded human history, people ... used to paint things blue, often with limited success. Most ...
... become resistant to antibiotics are a serious threat to human ... a new project, researchers at the University of Gothenburg are ... evolution, in order to ensure that the drugs of today ... organisms to antibiotics is particularly serious in drugs against fungi. ...
Cached Biology News:Statement of ESHRE on the European Commission proposal of viral screening 2Accidental discovery produces durable new blue pigment for multiple applications 2Slowing evolution to stop drug resistance 2
(Date:7/1/2015)... InferMed , s ... will augment ... s olutions suite   Elsevier , ... and services, announced today the acquisition of  InferMed , a ... company. InferMed,s Arezzo technology supports clinicians in choosing ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... pathogen transmission. CTI’ new Medical Joysticks have an impermeable molecular barrier protection ... an operator control device that will increase healthcare worker safety and reduce financial ...
(Date:6/30/2015)... July 1, 2015 R-Japan Co.,Ltd. obtained the license ... of Regenerative Medicine from the Ministry of Health, Labour and ... 2015. The fact that R- Japan ... the auditing from Pharmaceuticals and Medical Devices Agency (PMDA) on ... it to provide stem cell manufacturing service to medical institutions. ...
(Date:6/30/2015)... CALGARY , June 30, 2015 /PRNewswire/ - ... ("Shareholders") of common shares of Resverlogix have approved ... to Eastern Capital Limited of 5,600,000 units at ... Private Placement"), each unit being comprised of one ... for aggregate proceeds of approximately CAD$15 million; and ...
Breaking Biology Technology:Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4Sanitized Medical Joysticks for a Safer and Healthier Work Environment 2R-Japan Obtained Autologous Stem Cell Manufacturing License from the Ministry of Health, Labour and Welfare 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 3
... Last weeks column spurred enough e-mail to suggest that I ... of). , ,As one reader stated, the idea of getting ... was illegal and non-ethical, but Im chalking that up to ... can be rid of technology. That genie just wont go ...
... University of Wisconsin-Madison researchers announced Wednesday they have ... of Health to continue research on protein structure. , ... the Protein Structure Initiative, a program initiated by the NIH ... structures. UW-Madison's Center for Eukaryotic Structural Genomics is ...
... - API Software, Inc. announced today ... multiple components of the company's API LaborWorkx product. , ... in the United States, with customers ranging in size ... ,Hospitals recently purchasing API software include: , , St. ...
Cached Biology Technology:Lamenting the loss of leisure 2Lamenting the loss of leisure 3UW-Madison awarded $20 million grant for protein research 2UW-Madison awarded $20 million grant for protein research 3
...
... B-Phycoerythrin Labeling Kit - NH2 is primarily ... for immunostaining and cellular proteins for tracing. ... has succinimidyl group (NHS), and can easily ... of IgG or other proteins without any ...
Mouse polyclonal antibody raised against a partial recombinant RDH5. NCBI Entrez Gene ID = 5959...
Mouse monoclonal antibody raised against a partial recombinant KRT4. NCBI Entrez Gene ID = KRT4...
Biology Products: