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UMass Medical School scientist named 2012 Pew Latin-American Fellow in the Biomedical Sciences
Date:6/13/2012

other proteins called transcription factors (TF) that dictate where and when cytokine genes are expressed. Inappropriate release of cytokines has been associated with several diseases including many cancers, autoimmune diseases and immune deficiencies. Using an innovative combination of computational and experimental technology, Fuxman Bass is working to identify the network of transcription factors that interact with all the genes that encode human cytokines and assess how loss of these factors affects their production. Fully understanding the complex system of cytokine production could lead to new treatments for cancer, infection and autoimmune diseases.

"I'm working to assemble and characterize a cytokine gene regulatory network by identifying the transcription factors that regulate cytokine genes using a new experimental platform developed in the Walhout lab called enhanced yeast one-hybrid," said Fuxman Bass. "This work will greatly contribute to the understanding of cytokine regulation during immune responses and will provide a framework to identify new therapeutic targets for multiple immune related diseases."

"Juan is an exceptional scientist who has made significant contributions in the lab to our understanding systems biology," said Walhout. "This award is a reflection of his outstanding work and is well deserved."

Fuxman Bass, who received a doctorate in biology from the University of Buenos Aires in 2010, is the first UMass Medical School scientist to be named a Pew Latin American Fellow. The Pew Latin American Fellows in the Biomedical Sciences program provides a stipend in each of two years for postdoctoral training in the United States and an additional $35,000 payment when the fellow returns to Latin America for the purchase of supplies and equipment to help establish his/her independent laboratory. The program was launched in 1991 to help develop and advance the scientific network of highly trained researchers and to fost
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Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

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