Date:6/26/2012

plex role for small-RNA systems in epigenetic programming," said Mello. "It shows how piRNAs continuously scan all the genes expressed in the germline, constantly comparing each sequence to a memory of previous gene expression. When foreign genes are recognized and silenced, this new epigenetic knowledge can be passed down to successive generations. On the other hand, occasionally new genes are expressed, apparently stochastically, and this active state too can be passed on as a stable epigenetic memory, thus the organism effectively adopts the foreign gene as self."

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Contact: Jim Fessenden james.fessenden@umassmed.edu 508-856-2000 University of Massachusetts Medical School Source:Eurekalert

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