Navigation Links
UM School of Medicine finds new pathway critical to heart arrhythmia
Date:10/26/2011

kages molecules for the cell's use. Dr. Welling's lab found that the Golgi apparatus selects the Kir2.1 channel to travel to the surface of the cell in an unusual, signal-dependent manner. The signal determines where the Golgi apparatus sends the potassium channel and how many it sends and verifies that the channels are of quality. In patients with Andersen-Tawil Syndrome, the signal is faulty and fails to properly regulate the ion channels and their path to the cell surface.

"Elucidating the mechanisms behind this rare disease provides insight into more prevalent forms of arrhythmia such as heart failure," says Dr. Welling. "There is great interest in understanding the mechanisms by which cardiac ion channels are regulated. This new pathway may be an excellent target for therapeutic intervention for both Andersen-Tawil syndrome and the far more common condition, like arrhythmias associated with heart failure."

The study has implications beyond the science of the heart, he added. The class of ion channels the researchers examined includes about 12 other ion channels that control various body processes from cognition to the salt balance in the kidneys. The next step for his lab, Dr. Welling says, is to study this pathway in relation to the kidneys. It is possible the same pathway affects the entire class of channels and helps regulate all the body processes associated with them.


'/>"/>

Contact: Karen Robinson
karobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Color My Pyramid nutrition education program battles obesity in DC schools
2. identiMetrics & BIO-key(R) Provide Biometric Finger Scanning for School Food Service Nationwide
3. NJIT sustainability expert to discuss high performance schools at seminar
4. Students eat more whole grains when its gradually added to school lunch
5. Eliminating soda from school diets does not affect overall consumption
6. High school students paper published in prestigious college math journal
7. David Rose to present Howe School lecture on new technologies and business models, Jan. 29
8. Physically fit kids do better in school
9. Results of the third school nutrition dietary assessment study published
10. New York, Florida schools win awards at national student competition
11. Names turn preschoolers into vegetable lovers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal ... that pinpoints fine-scale differences in genetic ancestry of individuals ... Since immigrants first arrived more than four ... has served as a meeting place for peoples ... and the ongoing mixing of peoples with African, European, ...
(Date:12/17/2014)... N.C. , Dec. 16, 2014 Valencell, ... licensed its PerformTek biometric technology to industry leaders such ... highly accurate, clinically validated, biometric wearable products. These products ... 6-9 in Las Vegas . ... technology is accurate, flexible and robust – with the ...
(Date:12/11/2014)... 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition ... report to their offering. ... the adoption of multimodal biometric systems. Multimodal biometric ... individual for verification and identification purposes. This helps ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... as strawberry, clover, reed and ground elder naturally form ... a certain period of time by means of runners. ... each other via internal channels. They are therefore very ... to chat to each other about? Recently Stuefer ...
... Scientists have discovered how the zebrafish (Danio rerio) develops one ... growing list of tasks carried out by an important molecule ... cells to reproductive cells in the developing embryo. The ... which is distinctive because one of the four stripes running ...
... better understanding how antimicrobials bind and thereby get inactivated ... University of Illinois may have found a way to ... not a cure, this work has potential as a ... Gerard Wong a professor of materials science and engineering, ...
Cached Biology News:Study shows how the zebrafish gets his stripe 2Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials 2
(Date:12/24/2014)... (PRWEB) December 23, 2014 Earlier this ... James L. Sherley, director of the Adult Stem Cell ... an often overlooked and under appreciated unique property of ... by Distributed Stem Cells: Misunderstood in the Past, Important ... to congress participants. He gave the address at ...
(Date:12/24/2014)... 2014 The report provides ... its definition, classification, application and industry overview. ... process, and product cost structure. Production is ... analysis also covers upstream raw materials, equipment, ... trend and proposals. In the end, the ...
(Date:12/24/2014)... , Dec. 23, 2014 China Biologic ... "Company"), a leading fully integrated plasma-based biopharmaceutical company ... that its majority-owned subsidiary, Shandong Taibang Biological Products ... certification from the China Food and Drug Administration ... facility. As previously disclosed in the Company,s public ...
(Date:12/24/2014)... 23, 2014  Rock Creek Pharmaceuticals, Inc., (NASDAQ: ... a Clinical Trial Application (CTA) with the ... (MHRA) seeking regulatory approval to initiate clinical trials for ... Contingent on the Company receiving CTA regulatory ... trial to assess the safety, tolerability and dose escalation ...
Breaking Biology Technology:Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3
... Space ... the eighth scientific payload for Astrogenetix, a commercial biotech company created to use microgravity ... ... off from NASA’s Kennedy Space Center this morning, carrying on board the eighth scientific ...
... , Full enrollment occurs five months ahead of schedule , ... /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced ... clinical study of its lead drug RVX-208. "The completion of ... months ahead of our original schedule, is a very exciting ...
... , , , , ... Feb. 8 /PRNewswire-Asia-FirstCall/ -- 3SBio Inc. (Nasdaq:, ... China -based biotechnology company,focused on researching, developing, manufacturing and ... Panacor Bioscience Ltd. to develop and commercialize its,Nephoxil(R) pharmaceutical ...
Cached Biology Technology:Astrogenetix Continues MRSA Vaccine Development Onboard Endeavor 2Astrogenetix Continues MRSA Vaccine Development Onboard Endeavor 3Resverlogix Completes Patient Recruitment for ASSERT Trial 2Resverlogix Completes Patient Recruitment for ASSERT Trial 3Resverlogix Completes Patient Recruitment for ASSERT Trial 43SBio and Panacor Bioscience Enter Collaboration and License Agreement to Develop and Commercialize Nephoxil(R) for Hyperphosphatemia 23SBio and Panacor Bioscience Enter Collaboration and License Agreement to Develop and Commercialize Nephoxil(R) for Hyperphosphatemia 33SBio and Panacor Bioscience Enter Collaboration and License Agreement to Develop and Commercialize Nephoxil(R) for Hyperphosphatemia 4
GEL FILTRATION CAL KIT HMW, 1 EA. *Category: Gel Filtration Gels....
Mouse monoclonal [6C3] to JAB1 ( Abpromise for all tested applications). entrezGeneID: 10987 SwissProtID: O15386...
Human TGF-beta RIIb Affinity Purified Polyclonal Ab...
Human FGF R2 (alpha isoforms) MAb (Clone 98706)...
Biology Products: