UH Rainbow hopes to enroll 30 to 40 children through UH Rainbow pediatric offices. Six hundred children will participate in the nation. The study will be a randomized, double-blind study (the "gold standard" of research studies) meaning that neither the research subjects nor the physicians will know which half of the study group is receiving one of the active treatments and which half is receiving a placebo.
Can Vitamin D help patients with asthma?
UH Rainbow also participating in the VIDA (Vitamin D add-on therapy enhances corticosteroid responsiveness in Asthma) Study. Adolescents and adults ages 18 years of age and older who have been diagnosed with asthma and are non-smokers may be eligible for the study.
The purpose of this study is to learn if taking Vitamin D in addition to an inhaled steroid -- the most effective treatment for asthma available today -- will help prevent worsening asthma symptoms and asthma exacerbations in people who have low Vitamin D levels, estimated to be up to 30 percent of the population.
"Patients who live in urban areas, especially in the northern part of the United States, such as Ohio, tend to be deficient in Vitamin D. We also see higher rates of asthma in urban centers such as Cleveland," said Dr. Ross. "Patients who have low levels of Vitamin D tend to have more severe and harder to control asthma. One reason might be that having low levels of vitamin D make it harder for inhaled steroids to work well. Although we think of vitamin D as an important vitamin for healthy bones, there is increasing evidence that it is also important in the immune system and fighting inflammation."
"Despite how common asthma is, it remains poorly understood and, in many cases, poorly treated," said James Chmiel, M.D., principal investigator for the AsthmaNet site at UH Rainbow and associate profess
|Contact: George Stamatis|
University Hospitals Case Medical Center