Navigation Links
UH Case Medical Center leads international study
Date:11/9/2012

University Hospitals Case Medical Center's MacDonald Women's Hospital is leading an international trial investigating a first-of-its-kind on-demand drug for pre-menopausal women with sexual dysfunction. Led by Sheryl Kingsberg, PhD, this international Phase II study is one of the largest clinical studies to ever explore a "use-as-needed" treatment, Tefina, for women experiencing orgasmic disorder.

Tefina is a nasal gel containing testosterone and is inserted in the nose with an easy to use applicator 1-4 hours before sexual activity. The study, which will involve 240 patients in the U.S., Canada and Australia, will evaluate if there is an increase in the occurrence of orgasm over the treatment period, compared against baseline levels.

"Tefina is a potentially revolutionary treatment to restore women's ability to obtain orgasm and sexual satisfaction" says Dr. Kingsberg, Primary Investigator of the study and Chief of Behavioral Medicine at UH MacDonald Women's Hospital. "Low sexual satisfaction is linked to a lower sense of well being as well as to tension in relationships. We are hopeful that this be a real help for patients who say 'sex has become a chore.'"

Anorgasmia, also known as female orgasmic disorder, is defined as the persistent or recurrent delay in or absence of orgasm. Although this condition affects 1 in 5 women worldwide, there are no approved treatments for anorgasmia.

Tefina, developed by Trimel Pharmaceutical Corporation, is a self-administered low-dose testosterone gel. The testosterone is absorbed through the nasal lining, resulting in a rise in levels throughout the body. Low testosterone is linked to low sexual desire and the development of climax problems. Testosterone therapy not only improves sexual desire through central actions in the brain but also results in increased vaginal blood flow, which is critical for sexual satisfaction.

"Female orgasmic disorder can be very frustrating for women who have previously enjoyed a satisfying sexual relationship," says Dr. Kingsberg, who is also Professor at Case Western Reserve University School of Medicine. "There is a vast need for new treatments for women with sexual difficulties as previous studies have shown that at least 5 percent of women are unable to achieve orgasm. Historically we have had little to offer women and progress has lagged way behind that of treatment for male sexual problems."


'/>"/>

Contact: Alicia Reale
alicia.reale@uhhospitals.org
216-844-5158
University Hospitals Case Medical Center
Source:Eurekalert

Related biology news :

1. Medical devices powered by the ear itself
2. NCH partners with Silicon Valley to market high-end diagnostic and medical research software
3. US investment in biomedical and health research on downward trend
4. Marc Travel Awards announced for the 2012 Biomedical Engineering Society Annual Meeting
5. NIBIB and HHMI announce graduate biomedical training awards
6. Dr. Tom Maniatis honored with 2012 Lasker-Koshland Special Achievement Award in Medical Science
7. University of Alberta medical scientists first in the world to look at structure of vital molecule
8. CNIO participates in the ENCODE project: A stride forward in biomedical research
9. MU celebrates $5 million partnership for advancing biomedical discoveries
10. £30 million boost for biomedical engineering research
11. Reproducibility Initiative to increase the value of biomedical research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... , Dec. 15, 2016   WaferGen Bio-systems, Inc. ... genomics technology company, announced today that on December 13, ... Department of The Nasdaq Stock Market LLC which acknowledged ... price of WaferGen,s common stock had been at $1.00 ... has regained compliance with Listing Rule 5550(a)(2) of the ...
(Date:12/15/2016)... , Dec. 14, 2016 "Increase in ... biometrics market" The mobile biometrics market is expected to ... 49.33 billion by 2022, at a CAGR of 29.3% ... factors such as the growing demand for smart devices, ... transactions. "Software component is expected to grow ...
(Date:12/7/2016)... According to a new market research report "Emotion Detection and Recognition Market ... Application Area, End User, And Region - Global Forecast to 2021", published by ... 2016 to USD 36.07 Billion by 2021, at a Compound Annual Growth Rate ... ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:1/20/2017)... 20, 2017 Stock-Callers.com explores the ... influenced the most recent performances of select equities. In ... RGLS ), Abeona Therapeutics Inc. (NASDAQ: ... ), and Sage Therapeutics Inc. (NASDAQ: SAGE ... View Research, global Biotech market size is expected to reach $604.40 billion by ...
(Date:1/19/2017)... Jan 19, 2017 Research and Markets has ... Technology, Biomolecules, Cancer Type, Application - Global Opportunity Analysis and Industry ... ... the global market is projected to reach $15,737 million by 2022 ... 2016 to 2022. Omic technologies segment accounted for ...
(Date:1/19/2017)... Research and Markets ... announced the addition of the "Implantable Biomaterials Market ... report to their offering. Report Highlights: ... analysis on current and future market trends to identify the investment opportunities ... the base numbers Key market trends across the business ...
(Date:1/19/2017)... 19, 2017  ArmaGen, Inc., today announced that ... as chief executive officer, as well as a ... to ArmaGen more than 17 years of executive ... of biotherapeutics and pharmaceuticals. "Mathias ... experience and skillset necessary to lead ArmaGen to ...
Breaking Biology Technology: